Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     breast cancer BARD1* Bard1* 3 models Alliance of Genome Resources
breast cancer BRCA1* Brca1* 11 models Alliance of Genome Resources
breast cancer BRCA2* Brca2* 6 models Alliance of Genome Resources
breast cancer CAV1* Cav1* 1 model Alliance of Genome Resources
breast cancer ESR1* Esr1* 1 model Alliance of Genome Resources
breast cancer MYC* Myc*, Bmyc 7 models Alliance of Genome Resources
breast cancer PIK3CA* Pik3ca* 4 models Alliance of Genome Resources
breast cancer TP53* Trp53* 14 models Alliance of Genome Resources
     breast cancer APC Apc* 2 models Alliance of Genome Resources
breast cancer ERBB2 Erbb2* 4 models Alliance of Genome Resources
breast cancer ESPL1 Espl1* 1 model Alliance of Genome Resources
breast cancer HGF Hgf* 2 models Alliance of Genome Resources
breast cancer MET Met* 1 model Alliance of Genome Resources
breast cancer SMARCA4 Smarca4* 1 model Alliance of Genome Resources
breast cancer STAT1 Stat1* 1 model Alliance of Genome Resources
breast cancer WNT1 Wnt1* 2 models Alliance of Genome Resources
breast metaplastic carcinoma CCN6 Ccn6* 1 model Alliance of Genome Resources
     breast adenocarcinoma TNF* Tnf   Alliance of Genome Resources
breast adenocarcinoma KSR1* Ksr1   Alliance of Genome Resources
breast adenocarcinoma CCNE1* Ccne1   Alliance of Genome Resources
breast adenocarcinoma BRCA1* Brca1   Alliance of Genome Resources
breast angiosarcoma KDR* Kdr   Alliance of Genome Resources
breast angiosarcoma PTPRB* Ptprb   Alliance of Genome Resources
breast angiosarcoma PIK3CA* Pik3ca   Alliance of Genome Resources
breast cancer ACE* Ace   Alliance of Genome Resources
breast cancer ACSL3* Acsl3   Alliance of Genome Resources
breast cancer ADAM28* Adam28   Alliance of Genome Resources
breast cancer ADIPOQ* Adipoq   Alliance of Genome Resources
breast cancer ADIPOR1* Adipor1   Alliance of Genome Resources
breast cancer ADM* Adm   Alliance of Genome Resources
breast cancer AGT* Agt   Alliance of Genome Resources
breast cancer AGTR1* Agtr1a, Agtr1b   Alliance of Genome Resources
breast cancer AKT1* Akt1   Alliance of Genome Resources
breast cancer ALOX5AP* Alox5ap   Alliance of Genome Resources
breast cancer APEX1* Apex1   Alliance of Genome Resources
breast cancer APOE* Apoe   Alliance of Genome Resources
breast cancer AREG* Areg   Alliance of Genome Resources
breast cancer ARID1A* Arid1a   Alliance of Genome Resources
breast cancer ATM* Atm   Alliance of Genome Resources
breast cancer BCAS2* Bcas2   Alliance of Genome Resources
breast cancer BCL2L1* Bcl2l1   Alliance of Genome Resources
breast cancer BIK* Bik   Alliance of Genome Resources
breast cancer BIRC2* Birc2   Alliance of Genome Resources
breast cancer BRIP1* Brip1   Alliance of Genome Resources
breast cancer CASP7* Casp7   Alliance of Genome Resources
breast cancer CASP8* Casp8   Alliance of Genome Resources
breast cancer CBX7* Cbx7   Alliance of Genome Resources
breast cancer CCNB1* Ccnb1, Ccnb1-ps   Alliance of Genome Resources
breast cancer CCND2* Ccnd2   Alliance of Genome Resources
breast cancer CCR5* Ccr5   Alliance of Genome Resources
breast cancer CDH1* Cdh1   Alliance of Genome Resources
breast cancer CDH13* Cdh13   Alliance of Genome Resources
breast cancer CDK1* Cdk1   Alliance of Genome Resources
breast cancer CDKN1B* Cdkn1b   Alliance of Genome Resources
breast cancer CDKN2A* Cdkn2a   Alliance of Genome Resources
breast cancer CHEK2* Chek2   Alliance of Genome Resources
breast cancer CLU* Clu   Alliance of Genome Resources
breast cancer COMT* Comt   Alliance of Genome Resources
breast cancer CTLA4* Ctla4   Alliance of Genome Resources
breast cancer CTSD* Ctsd   Alliance of Genome Resources
breast cancer CYB5R3* Cyb5r3   Alliance of Genome Resources
breast cancer CYP1A1* Cyp1a1   Alliance of Genome Resources
breast cancer CYP1A2* Cyp1a2   Alliance of Genome Resources
breast cancer CYP1B1* Cyp1b1   Alliance of Genome Resources
breast cancer CYP2C19*, CYP2C8, CYP2C9, CYP2C18 Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66   Alliance of Genome Resources
breast cancer CYP17A1* Cyp17a1   Alliance of Genome Resources
breast cancer CYP19A1* Cyp19a1   Alliance of Genome Resources
breast cancer DUSP1* Dusp1   Alliance of Genome Resources
breast cancer EBAG9* Ebag9   Alliance of Genome Resources
breast cancer EIF3H* Eif3h   Alliance of Genome Resources
breast cancer ENG* Eng   Alliance of Genome Resources
breast cancer ERCC1* Ercc1   Alliance of Genome Resources
breast cancer ERCC2* Ercc2   Alliance of Genome Resources
breast cancer ESR2* Esr2   Alliance of Genome Resources
breast cancer F5* F5   Alliance of Genome Resources
breast cancer F10* F10   Alliance of Genome Resources
breast cancer FANCA* Fanca   Alliance of Genome Resources
breast cancer FANCC* Fancc   Alliance of Genome Resources
breast cancer FANCD2* Fancd2   Alliance of Genome Resources
breast cancer FAS* Fas   Alliance of Genome Resources
breast cancer FGFR2* Fgfr2   Alliance of Genome Resources
breast cancer FOXA1* Foxa1   Alliance of Genome Resources
breast cancer GNRH1* Gnrh1   Alliance of Genome Resources
breast cancer GPX1* Gpx1   Alliance of Genome Resources
breast cancer GRB2* Grb2   Alliance of Genome Resources
breast cancer GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
breast cancer GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
breast cancer GSTT1* Gstt1   Alliance of Genome Resources
breast cancer HLA-DQA1*, HLA-DQA2 H2-Aa   Alliance of Genome Resources
breast cancer HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 H2-Eb1, H2-Eb2   Alliance of Genome Resources
breast cancer H19*  
breast cancer HFE* Hfe   Alliance of Genome Resources
breast cancer HMMR* Hmmr   Alliance of Genome Resources
breast cancer IFNG* Ifng   Alliance of Genome Resources
breast cancer IGFBP3* Igfbp3   Alliance of Genome Resources
breast cancer IKBKB* Ikbkb   Alliance of Genome Resources
breast cancer IL1B* Il1b   Alliance of Genome Resources
breast cancer IL6* Il6   Alliance of Genome Resources
breast cancer IL13RA2* Il13ra2   Alliance of Genome Resources
breast cancer IL18* Il18   Alliance of Genome Resources
breast cancer KAT6B* Kat6b   Alliance of Genome Resources
breast cancer KDM4B* Kdm4b   Alliance of Genome Resources
breast cancer KDM4C* Kdm4c   Alliance of Genome Resources
breast cancer KDM5B* Kdm5b   Alliance of Genome Resources
breast cancer KRAS* Kras 1 model Alliance of Genome Resources
breast cancer KRT81*, KRT83, KRT86, KRT87P Krt81, Krt83, Krt86, Krt87   Alliance of Genome Resources
breast cancer LHCGR* Lhcgr   Alliance of Genome Resources
breast cancer LTA* Lta   Alliance of Genome Resources
breast cancer MANF* Manf   Alliance of Genome Resources
breast cancer MAP3K1* Map3k1   Alliance of Genome Resources
breast cancer MCPH1* Mcph1   Alliance of Genome Resources
breast cancer MGMT* Mgmt   Alliance of Genome Resources
breast cancer MKI67* Mki67   Alliance of Genome Resources
breast cancer MMP1* Mmp1a, Mmp1b   Alliance of Genome Resources
breast cancer MMP3* Mmp3   Alliance of Genome Resources
breast cancer MMP8* Mmp8   Alliance of Genome Resources
breast cancer MSH2* Msh2   Alliance of Genome Resources
breast cancer MUC1* Muc1   Alliance of Genome Resources
breast cancer NBN* Nbn   Alliance of Genome Resources
breast cancer NCOA6* Ncoa6   Alliance of Genome Resources
breast cancer NFKB1* Nfkb1   Alliance of Genome Resources
breast cancer NOD2* Nod2   Alliance of Genome Resources
breast cancer NOS3* Nos3   Alliance of Genome Resources
breast cancer NQO2* Nqo2   Alliance of Genome Resources
breast cancer OGG1* Ogg1   Alliance of Genome Resources
breast cancer PAK1* Pak1   Alliance of Genome Resources
breast cancer PHB1* Phb1   Alliance of Genome Resources
breast cancer PON1* Pon1   Alliance of Genome Resources
breast cancer PPM1D* Ppm1d   Alliance of Genome Resources
breast cancer PPP2R2B* Ppp2r2b   Alliance of Genome Resources
breast cancer PRKAA1* Prkaa1   Alliance of Genome Resources
breast cancer PSEN2* Psen2   Alliance of Genome Resources
breast cancer PTEN* Pten 5 models Alliance of Genome Resources
breast cancer PTK2B* Ptk2b   Alliance of Genome Resources
breast cancer PTPN13* Ptpn13   Alliance of Genome Resources
breast cancer RAD51* Rad51   Alliance of Genome Resources
breast cancer RAD54L* Rad54l   Alliance of Genome Resources
breast cancer RASSF1* Rassf1   Alliance of Genome Resources
breast cancer RB1CC1* Rb1cc1   Alliance of Genome Resources
breast cancer RELB* Relb   Alliance of Genome Resources
breast cancer RNF20* Rnf20   Alliance of Genome Resources
breast cancer RUNX3* Runx3   Alliance of Genome Resources
breast cancer SHMT1* Shmt1   Alliance of Genome Resources
breast cancer SLC22A18* Slc22a18   Alliance of Genome Resources
breast cancer SNW1* Snw1   Alliance of Genome Resources
breast cancer SOD2* Sod2   Alliance of Genome Resources
breast cancer SOX2* Sox2   Alliance of Genome Resources
breast cancer STAT3* Stat3   Alliance of Genome Resources
breast cancer SULT1A1*, SULT1A2, SULT1A3, SULT1A4 Sult1a1   Alliance of Genome Resources
breast cancer SULT1E1* Sult1e1   Alliance of Genome Resources
breast cancer TCF7L2* Tcf7l2   Alliance of Genome Resources
breast cancer TGFB1* Tgfb1   Alliance of Genome Resources
breast cancer TLR2* Tlr2   Alliance of Genome Resources
breast cancer TLR4* Tlr4   Alliance of Genome Resources
breast cancer TNF* Tnf   Alliance of Genome Resources
breast cancer TNFAIP3* Tnfaip3   Alliance of Genome Resources
breast cancer TP73* Trp73   Alliance of Genome Resources
breast cancer TSG101* Tsg101   Alliance of Genome Resources
breast cancer TWIST1* Twist1   Alliance of Genome Resources
breast cancer UBR5* Ubr5   Alliance of Genome Resources
breast cancer UGT1A1* Ugt1a1   Alliance of Genome Resources
breast cancer VDR* Vdr   Alliance of Genome Resources
breast cancer WIF1* Wif1   Alliance of Genome Resources
breast cancer WRN* Wrn   Alliance of Genome Resources
breast cancer XPO5* Xpo5   Alliance of Genome Resources
breast cancer XRCC3* Xrcc3   Alliance of Genome Resources
breast carcinoma CADM1* Cadm1   Alliance of Genome Resources
breast carcinoma NQO2* Nqo2   Alliance of Genome Resources
breast carcinoma MRE11* Mre11a   Alliance of Genome Resources
breast carcinoma LZTS1* Lzts1   Alliance of Genome Resources
breast carcinoma HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 H2-Eb1, H2-Eb2   Alliance of Genome Resources
breast carcinoma FBXO11* Fbxo11   Alliance of Genome Resources
breast carcinoma ESR1* Esr1   Alliance of Genome Resources
breast carcinoma EGFR* Egfr   Alliance of Genome Resources
breast carcinoma DDR1* Ddr1   Alliance of Genome Resources
breast carcinoma THRB* Thrb   Alliance of Genome Resources
breast carcinoma TIMP3* Timp3   Alliance of Genome Resources
breast carcinoma TSG101* Tsg101   Alliance of Genome Resources
breast carcinoma TWIST1* Twist1   Alliance of Genome Resources
breast carcinoma VEGFC* Vegfc   Alliance of Genome Resources
breast carcinoma WNT2* Wnt2   Alliance of Genome Resources
breast carcinoma CAV1* Cav1   Alliance of Genome Resources
breast carcinoma CDH13* Cdh13   Alliance of Genome Resources
breast carcinoma CDK4* Cdk4   Alliance of Genome Resources
breast carcinoma BIN1* Bin1   Alliance of Genome Resources
breast carcinoma THOC5* Thoc5   Alliance of Genome Resources
breast carcinoma TFRC* Tfrc   Alliance of Genome Resources
breast carcinoma STAT1* Stat1   Alliance of Genome Resources
breast carcinoma RHOA* Rhoa   Alliance of Genome Resources
breast carcinoma DCN* Dcn   Alliance of Genome Resources
breast carcinoma CXCL12* Cxcl12   Alliance of Genome Resources
breast carcinoma in situ IGF2R* Igf2r   Alliance of Genome Resources
breast ductal carcinoma BCAR1* Bcar1   Alliance of Genome Resources
breast ductal carcinoma RICTOR* Rictor   Alliance of Genome Resources
breast ductal carcinoma CD44* Cd44   Alliance of Genome Resources
ductal carcinoma in situ CCND2* Ccnd2   Alliance of Genome Resources
ductal carcinoma in situ HOXB13* Hoxb13   Alliance of Genome Resources
ductal carcinoma in situ NOTCH4* Notch4   Alliance of Genome Resources
ductal carcinoma in situ PAK2* Pak2   Alliance of Genome Resources
ductal carcinoma in situ RELA* Rela   Alliance of Genome Resources
ductal carcinoma in situ SRC* Src   Alliance of Genome Resources
ductal carcinoma in situ BRCA2* Brca2   Alliance of Genome Resources
estrogen-receptor positive breast cancer ADAM28* Adam28   Alliance of Genome Resources
estrogen-receptor positive breast cancer PIK3CA* Pik3ca   Alliance of Genome Resources
female breast cancer CHEK2* Chek2   Alliance of Genome Resources
female breast cancer CTCF* Ctcf   Alliance of Genome Resources
female breast cancer FANCI* Fanci   Alliance of Genome Resources
female breast cancer MAST1* Mast1   Alliance of Genome Resources
female breast cancer PALB2* Palb2   Alliance of Genome Resources
female breast cancer ATM* Atm   Alliance of Genome Resources
female breast cancer RTEL1* Rtel1   Alliance of Genome Resources
female breast cancer POLH* Polh   Alliance of Genome Resources
female breast carcinoma FGFR2* Fgfr2   Alliance of Genome Resources
invasive ductal carcinoma CSNK1E*, TPTEP2-CSNK1E Csnk1e   Alliance of Genome Resources
invasive ductal carcinoma CDKN2A* Cdkn2a   Alliance of Genome Resources
invasive ductal carcinoma AKT1* Akt1   Alliance of Genome Resources
invasive ductal carcinoma ADAM28* Adam28   Alliance of Genome Resources
invasive ductal carcinoma ABCB1* Abcb1a, Abcb1b   Alliance of Genome Resources
invasive ductal carcinoma XRCC1* Xrcc1   Alliance of Genome Resources
invasive ductal carcinoma UBR5* Ubr5   Alliance of Genome Resources
invasive ductal carcinoma RUNX3* Runx3   Alliance of Genome Resources
invasive ductal carcinoma NEFL* Nefl   Alliance of Genome Resources
invasive ductal carcinoma FHIT* Fhit   Alliance of Genome Resources
invasive ductal carcinoma DLG1* Dlg1   Alliance of Genome Resources
invasive lobular carcinoma CDH1* Cdh1 1 model Alliance of Genome Resources
invasive lobular carcinoma CD44* Cd44   Alliance of Genome Resources
invasive lobular carcinoma CCND2* Ccnd2   Alliance of Genome Resources
invasive lobular carcinoma CCND1* Ccnd1   Alliance of Genome Resources
male breast cancer CHEK2* Chek2   Alliance of Genome Resources
mammary Paget's disease ERBB2* Erbb2   Alliance of Genome Resources
sporadic breast cancer MLH1* Mlh1   Alliance of Genome Resources
sporadic breast cancer ESR1* Esr1   Alliance of Genome Resources
sporadic breast cancer PHB1* Phb1   Alliance of Genome Resources
sporadic breast cancer PTEN* Pten   Alliance of Genome Resources
triple-receptor negative breast cancer KDM6A* Kdm6a   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  breast cancer T(9;17)138Ca 1 model
  breast cancer Tg(C3-1-TAg)cJeg 1 model
  breast cancer Tg(Erbb2-Erbb2*V664E)#Led 1 model
  breast cancer Tg(MMTV-AURKA)#Cxd 2 models
  breast cancer Tg(MMTV-DMTF1_i2)7Kai 1 model
  breast cancer Tg(MMTV-ENPP2)20Gbm 1 model
  breast cancer Tg(MMTV-ENPP2)21Gbm 1 model
  breast cancer Tg(MMTV-ENPP2)#Gbm 1 model
  breast cancer Tg(MMTV-Erbb2)1Pv 1 model
  breast cancer Tg(MMTV-ERBB2)5Erick 1 model
  breast cancer Tg(MMTV-Erbb2)9Pjo 1 model
  breast cancer Tg(MMTV-Erbb2)10Pjo 1 model
  breast cancer Tg(MMTV-Erbb2)12Pjo 1 model
  breast cancer Tg(MMTV-Erbb2)17Pjo 1 model
  breast cancer Tg(MMTV-Erbb2)NK1Mul 1 model
  breast cancer Tg(MMTV-Erbb2*,-cre)1Mul 1 model
  breast cancer Tg(MMTV-ERBB2*,-luc)6157Aami 1 model
  breast cancer Tg(MMTV-Espl1)1Pati 1 model
  breast cancer Tg(MMTV-LPAR1)2Gbm 1 model
  breast cancer Tg(MMTV-LPAR1)7Gbm 1 model
  breast cancer Tg(MMTV-LPAR1)27Gbm 1 model
  breast cancer Tg(MMTV-LPAR1)#Gbm 1 model
  breast cancer Tg(MMTV-LPAR2)3Gbm 1 model
  breast cancer Tg(MMTV-LPAR2)6Gbm 1 model
  breast cancer Tg(MMTV-LPAR2)#Gbm 1 model
  breast cancer Tg(MMTV-LPAR3)3Gbm 1 model
  breast cancer Tg(MMTV-LPAR3)22Gbm 1 model
  breast cancer Tg(MMTV-LPAR3)#Gbm 1 model
  breast cancer Tg(MMTV-Myc)WT13Jrn 1 model
  breast cancer Tg(MMTV-Myc)WT21Jrn 1 model
  breast cancer Tg(MMTV-Myc*T58A)TA14Jrn 1 model
  breast cancer Tg(MMTV-Myc*T58A)TA39Jrn 1 model
  breast cancer Tg(MMTV-Myc*T58A)TA41Jrn 1 model
  breast cancer Tg(MMTV-NCOA3)#Mybr 1 model
  breast cancer Tg(MMTV-neu/OT-I/OT-II)CBnel 2 models
  breast cancer Tg(MMTV-PyVT)634Mul 2 models
  breast cancer Tg(MMTV-PyVT)#Mul 1 model
  breast cancer Tg(MMTV-PyVT*Y250F)250-2Mul 1 model
  breast cancer Tg(MMTV-PyVT*Y315F*Y322F)Db-1Mul 1 model
  breast cancer Tg(MMTV-TGFBR2)7Hlm 1 model
  breast cancer Tg(MMTVneu)202Mul 4 models
  breast cancer Tg(TetO-Erbb2)1Lach 1 model
  breast cancer Tg(tetO-ERBB2)#Jjz 1 model
  breast cancer Tg(tetO-Esr1)#Paf 1 model
  breast cancer Tg(tetO-IGF1R)1Ramo 1 model
  breast cancer Tg(tetO-Kras2)12Hev 3 models
  breast cancer Tg(tetO-MYC)1Lach 3 models
  breast cancer Tg(tetO-PIK3CA*H1047R,-luc)2239Jjz 1 model
  breast cancer Tg(tetO-PyVT,-cre)1Mul 1 model
  breast cancer Tg(Trp53R172H)8512Jmr 2 models
  breast cancer Tg(Wap-Hgf)402Mig 2 models
  breast cancer Tg(Wap-TAg)NP8Depp 1 model
  breast cancer Tg(WapTAg)1Knw 1 model
  breast cancer Tg(WapTAg)3Knw 1 model
  breast cancer Tg(Wnt1)1Hev 2 models
  ductal carcinoma in situ Tg(Wap-TAg)1Depp 1 model
  ductal carcinoma in situ Tg(Wap-TAg)NP8Depp 1 model