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Krt83 Gene Detail
Summary
  • Symbol
    Krt83
  • Name
    keratin 83
  • Synonyms
    5430421N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3690448
    NCBI Gene: 100126226
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101383011-101389393 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3690448
 protein coding gene Chr15:101383011-101389393 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022376
 protein coding gene Chr15:103560561-103568735 (-)
A/J MGP_AJ_G0022338
 protein coding gene Chr15:99454834-99462610 (-)
AKR/J MGP_AKRJ_G0022314
 protein coding gene Chr15:102484013-102490220 (-)
BALB/cJ MGP_BALBcJ_G0022342
 protein coding gene Chr15:99558835-99566538 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0022790
 protein coding gene Chr15:107421846-107431192 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020315
 protein coding gene Chr15:95184280-95190615 (-)
CAST/EiJ MGP_CASTEiJ_G0021636
 protein coding gene Chr15:103442405-103453312 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0022208
 protein coding gene Chr15:98790296-98797082 (-)
FVB/NJ MGP_FVBNJ_G0022187
 protein coding gene Chr15:97845518-97852002 (-)
LP/J MGP_LPJ_G0022278
 protein coding gene Chr15:103703806-103710316 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022208
 protein coding gene Chr15:114808146-114819785 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022804
 protein coding gene Chr15:102526736-102534111 (-)
PWK/PhJ MGP_PWKPhJ_G0021375
 protein coding gene Chr15:98951358-98958754 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0021686
 protein coding gene Chr15:103166207-103175017 (-)



Homology
more
  • Human Ortholog
    KRT83, keratin 83
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT83, keratin 83
  • Synonyms
    EKVP5, Hb-3, HB3, KRTHB3, MNLIX
  • Links
    NCBI Gene ID: 3889
    neXtProt AC: NX_P78385
    UniProt: P78385

  • Chr Location
    12q13.13; chr12:52314301-52321398 (-)  GRCh38
  • Human Ortholog
    KRT87P, keratin 87, pseudogene
  • Synonyms
    KRT121P, KRTHBP4, psihHbD
  • Links
    NCBI Gene ID: 85349
    UniProt: A6NCN2

  • Chr Location
    12q13.13; chr12:52250466-52258553 (-)  GRCh38
Human Diseases
more
  • Diseases
    4 with human KRT81,KRT83,KRT86 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100126226 NCBI Gene Model | MGI Sequence Detail 6383 C57BL/6J ±  kb
transcript NM_001201323 RefSeq | MGI Sequence Detail 1775 C57BL/6  
polypeptide NP_001188252 RefSeq | MGI Sequence Detail 479 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR018039 Intermediate filament protein, conserved site
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 45
    Diseases 1
    Gene Ontology 1
    Phenotypes 30
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory