Excel File Text File All mouse models of artery disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      aortic aneurysm \Agtr2tm1Tin/Y
\Efemp2tm1.1Hiya/\Efemp2tm1.2Hiya
\Tg(Tagln-cre)1Her/0		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL J:213282 View
aortic aneurysm \Efemp2tm1.1Hiya/\Efemp2tm1.2Hiya
\Tg(Tagln-cre)1Her/0		 involves: 129S6/SvEvTac * C57BL/6 * SJL J:213282 View
arterial calcification of infancy \Enpp1asj-2J/\Enpp1asj-2J BALB/cJ-Enpp1asj-2J/GrsrJ J:215824 View
arterial calcification of infancy \Enpp1asj/\Enpp1asj C57BL/6J-Enpp1asj/GrsrJ J:201689 View
essential hypertension \Nos3tm1Gdk/\Nos3tm1Gdk involves: 129P2/OlaHsd * C57BL/6 J:46061 View
essential hypertension \Nos3tm1Plh/\Nos3tm1Plh involves: 129S4/SvJae J:28778 View
essential hypertension \Nos3tm1Unc/\Nos3tm1Unc involves: 129P2/OlaHsd J:103153 View
Marfan syndrome \Fbn1tm1Hcd/\Fbn1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:91349, J:94428 View
Marfan syndrome \Fbn1tm1Lper/\Fbn1+ involves: 129/Sv * C57BL/6 * CD-1 J:167276 View
Marfan syndrome \Fbn1tm1Lper/\Fbn1+ involves: 129/Sv * CD-1 J:167276 View
Marfan syndrome \Fbn1tm1Rmz/\Fbn1tm1Rmz involves: 129S4/SvJae * C57BL/6J J:43199 View
Marfan syndrome \Fbn1tm2Rmz/\Fbn1tm2Rmz involves: 129S1/Sv * 129X1/SvJ J:54081 View
Marfan syndrome \Fbn1tm3Rmz/\Fbn1tm3Rmz Not Specified J:110586 View
Marfan syndrome \Fbn1Tsk/\Fbn1+ B6.Cg-Fbn1Tsk J:30961 View
Marfan syndrome \Fbn1Tsk/\Fbn1+ B10.D2/(58N)Sn J:21512 View
persistent fetal circulation syndrome \Foxf1em1Vvk/\Foxf1+ involves: C57BL/6 * DBA/2 J:296328 View
supravalvular aortic stenosis \Elntm1Dyl/\Eln+ B6.129-Elntm1Dyl J:86535 View
supravalvular aortic stenosis \Elntm1Dyl/\Eln+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:51109 View
      aortic aneurysm \Atp7aMo-blo/\Atp7a+ Not Specified J:5516 View
aortic aneurysm \Atp7aMo-blo/Y Not Specified J:5516, J:15796 View
aortic aneurysm \Klf15tm1Jain/\Klf15tm1Jain B6.129X1-Klf15tm1Jain J:167880 View
aortic dissection \Best3tm1.1Zhoj/\Best3tm1.1Zhoj
\Tg(Tagln-cre)1Her/0		 involves: C57BL/6 * SJL J:338981 View
aortic valve disease \Adamts19tm4a(EUCOMM)Wtsi/\Adamts19tm4a(EUCOMM)Wtsi C57BL/6N-Adamts19tm4a(EUCOMM)Wtsi J:287334 View
aortic valve disease \Adamts19tm4b(EUCOMM)Wtsi/\Adamts19tm4b(EUCOMM)Wtsi B6N(Cg)-Adamts19tm4b(EUCOMM)Wtsi J:287334 View
aortic valve disease \Egfrwa2/\Egfrwa2 involves: C57BL/6 J:241813 View
aortic valve disease \Egfrwa2/\Egfrwa2 STOCK Egfrwa2 J:60750 View
aortic valve disease \Elntm1Dyl/\Eln+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:184494 View
aortic valve disease \Hey2tm1Kkb/\Hey2tm1Kkb involves: 129S7/SvEvBrd * C57BL/6 J:216895 View
aortic valve disease \Nos3tm1Unc/\Nos3tm1Unc B6.129P2-Nos3tm1Unc/J J:103340 View
aortic valve disease \Rbpjtm1Kyo/\Rbpj+ involves: 129S2/SvPas * CD-1 J:187551 View
aortic valve stenosis \Tnftm2Gkl/\Tnf+ involves: 129S/SvEv * C57BL/6J J:264147 View
coronary artery disease \Kcnj8tm1Sse/\Kcnj8tm1Sse involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:76195 View
essential hypertension \Elntm1Dyl/\Eln+ B6.129-Elntm1Dyl J:86535 View
essential hypertension \Gata5tm1.2Nemr/\Gata5tm1.2Nemr Not Specified J:227997 View
hypertension \Nppatm1Unc/\Nppa+ involves: 129P2/OlaHsd * C57BL/6J J:76312 View
hypertension \Nppatm1Unc/\Nppatm1Unc involves: 129P2/OlaHsd * C57BL/6 J:76312 View
Marfan syndrome \Mus81tm1Esse/\Mus81tm1Esse involves: 129P2/OlaHsd * C57BL/6 J:133703 View
persistent fetal circulation syndrome \Nos3tm1Unc/\Nos3tm1Unc B6.129P2-Nos3tm1Unc/J J:98913 View
persistent fetal circulation syndrome \Ptentm1Hwu/\Ptentm1Hwu
\Twist2tm1.1(cre)Dor/\Twist2+		 B6.129-Twist2tm1.1(cre)Dor Ptentm1Hwu J:192736 View
pre-eclampsia \Apelatm1.2Brre/\Apelatm1.2Brre B6(Cg)-Apelatm1.2Brre J:244834 View
pre-eclampsia \Asb4tm1.2Cpat/\Asb4tm1.2Cpat involves: 129/SvEv J:238841 View
pre-eclampsia \Cdkn1ctm1Kat/\Cdkn1c+ involves: 129P2/OlaHsd J:102331 View
pre-eclampsia \Cdkn1ctm1Kat/\Cdkn1ctm1Kat involves: 129P2/OlaHsd J:102331 View
pre-eclampsia \Comttm1Kara/\Comttm1Kara involves: 129S4/SvJaeSor J:137276 View
pre-eclampsia \Ido1tm1.1Mkks/\Ido1tm1.1Mkks B6.Cg-Ido1tm1.1Mkks J:229059 View
pre-eclampsia \Notch2tm3Grid/\Notch2tm3Grid
\Tg(Tpbpa-cre,-EGFP)5Jcc/0		 involves: 129S1/Sv J:173527 View
pre-eclampsia \Ptgs1tm1Fun/\Ptgs1tm1Fun involves: 129S6/SvEvTac * C57BL/6 J:97351 View
pulmonary hypertension \Cavin1tm1Pfp/\Cavin1tm1Pfp B6.129S6-Cavin1tm1Pfp/J J:217258 View
      coronary artery disease \Apoetm1Unc/\Apoetm1Unc
\Scarb1tm1Kri/\Scarb1tm1Kri		 involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6 J:201999 View
Additional
Complex
Models		     aortic valve disease \Apobtm2Sgy/\Apobtm2Sgy
\Ldlrtm1Her/\Ldlrtm1Her
\Tg(Ins-Igf2)1Fbos/?		 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL J:227165 View
coronary artery disease \Abcc9tm1Cfb/\Abcc9tm1Cfb Not Specified J:78066 View
pre-eclampsia \Adatm1Mw/\Adatm1Mw
\Tg(Afp-ADA)#Xiay/0		 involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6J J:234143 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      coronary artery disease \Apoetm1Unc/\Apoetm1Unc
\Svep1em1Nost/\Svep1em1Nost		 involves: 129P2/OlaHsd * C57BL/6 J:304349 View
essential hypertension \Tnfrsf1btm1Imx/\Tnfrsf1btm1Imx involves: 129S7/SvEvBrd * C57BL/6 J:45147 View
Marfan syndrome \Fbn1tm3.2Lysa/\Fbn1+ Not Specified J:181493 View
Marfan syndrome \Fbn1tm3.2Lysa/\Fbn1tm3.2Lysa Not Specified J:181493 View
Moyamoya disease \Rnf213tm1.1Mfuji/\Rnf213tm1.1Mfuji involves: C57BL/6 J:229422 View