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Tg(Tpbpa-cre,-EGFP)5Jcc
Transgene Detail
Summary
Symbol: Tg(Tpbpa-cre,-EGFP)5Jcc
Name: transgene insertion 5, James C Cross
MGI ID: MGI:5287872
Synonyms: Tpbpa-Cre, Tpbpa-Cre-GFP
Transgene: Tg(Tpbpa-cre,-EGFP)5Jcc  Location: unknown  
Alliance: Tg(Tpbpa-cre,-EGFP)5Jcc page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Tpbpa-cre,-EGFP)5Jcc expression driven by 1 gene
 
Mutation detailsTransgenic mice were generated using a construct in which a cre recombinase-IRES-EGFP cassette was cloned downstream of the Tpbpa promoter. Three independent lines were obtained and all lines produced similar temporal and spatial expression patterns of cre-EGFP that correlated with those of the endogenous Tpbpa gene. Line 5 was used for further studies as it showed earliest onset of expression (around E8.0). Activity of cre recombinase in reporter assays also was detected by E8.0. (J:122534)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tpbpa (species not specified)
Summary of all recombinase alleles driven by Tpbpa.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
References
Original:  J:122534 Simmons DG, et al., Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol. 2007 Apr 15;304(2):567-78
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory