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Human Disease and Mouse Model Detail
Human Disease Prostate Cancer
OMIM ID: 176807
Human Phenotype Ontology associations
Synonyms Prostate Cancer
View all models View ALL (48) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     PTEN* Pten* View 14 models HomoloGene and HGNC
     ACPP Acpp* View 1 model HomoloGene and HGNC
APC Apc* View 1 model HomoloGene and HGNC
CTNNB1 Ctnnb1* View 1 model HomoloGene and HGNC
KRAS Kras* View 4 models HomoloGene and HGNC
MSMB Msmb* View 1 model HomoloGene and HGNC
NKX3-1 Nkx3-1* View 7 models HomoloGene and HGNC
TGFBR2 Tgfbr2* View 1 model HomoloGene and HGNC
     AR* Ar View 5 models HomoloGene and HGNC
BRCA2* Brca2 View 1 model HomoloGene and HGNC
CD82* Cd82   HomoloGene and HGNC
CDH1* Cdh1   HomoloGene and HGNC
CHEK2* Chek2   HomoloGene and HGNC
HIP1* Hip1   HomoloGene and HGNC
KLF6* Klf6   HomoloGene and HGNC
MAD1L1* Mad1l1   HomoloGene and HGNC
MSR1* Msr1   HomoloGene and HGNC
MXI1* Mxi1   HomoloGene and HGNC
ZFHX3* Zfhx3   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(ARR2/Pbsn-MYC)7Key View 1 model
  Tg(C3-1-TAg)cJeg View 1 model
  Tg(Ggamma-T)15Cps View 2 models
  Tg(Msmb-TAg)183-2Xuan View 1 model
  Tg(Msmb-TAg)186-3Xuan View 1 model
  Tg(Pbsn-Ar*E231G)7353Ng View 1 model
  Tg(Pbsn-ERG*)1Vv View 1 model
  Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp View 2 models
  Tg(Pbsn-MYC)6Key View 1 model
  Tg(Pbsn-MYC)#Tt View 1 model
  Tg(Pbsn-Tag)12T7fRjm View 1 model
  Tg(Pbsn-TAg)15Tvd View 2 models
  Tg(TRAMP)8247Ng View 6 models
References Disease References using Mouse Models (65)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory