Gt(ROSA)26Sortm1(JAG1)Xin
Targeted Allele Detail
|
Symbol: |
Gt(ROSA)26Sortm1(JAG1)Xin |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Li Xin |
MGI ID: |
MGI:5824048 |
Synonyms: |
Gt(ROSA)26Sortm1(JAG1,luc)Xin, R26-LSL-JAG1 |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
|
Alliance: |
Gt(ROSA)26Sortm1(JAG1)Xin page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:238768
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
C57BL/6
|
|
Allele Type: |
|
Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter) |
Mutation: |
|
Insertion
|
|
|
Gt(ROSA)26Sortm1(JAG1)Xin expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
JAG1 (182) |
|
|
|
|
|
Mutation details: The targeting vector was designed with (from 5' to 3') a loxP-flanked STOP cassette (neo with 3x polyA), jagged 1 (JAG1) human cDNA, and an internal ribosome entry site (IRES) fused to a luciferase sequence. This targeting vector was inserted between exons 1 and 2 of the Gt(ROSA)26Sor.
(J:238768)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
|
Original: |
J:238768 Su Q, et al., Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer. Oncogene. 2017 Feb 02;36(5):618-627 |
All: |
3 reference(s) |
|