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All mouse models of disease by infectious agent with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | COVID-19 | \Ace2em1(ACE2)Yowa/\Ace2em1(ACE2)Yowa | C57BL/6-Ace2em1(ACE2)Yowa | J:288243 | View | |||
| Creutzfeldt-Jakob disease | \Prnptm1(PRNP)Tkit/\Prnptm1(PRNP)Tkit | Not Specified | J:86603 | View | ||||
| Creutzfeldt-Jakob disease |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(Prnp*)#Rgab/0 |
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N | J:183170 | View | ||||
| Creutzfeldt-Jakob disease |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(Prnp*D177N*M128V)A21Rchi/0 |
involves: 129S7/SvEvBrd * C57BL/6 * CBA | J:142098 | View | ||||
| Creutzfeldt-Jakob disease |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(Prnp*D177N*M128V)A21Rchi/\Tg(Prnp*D177N*M128V)A21Rchi |
involves: 129S7/SvEvBrd * C57BL/6 * CBA | J:142098 | View | ||||
| Creutzfeldt-Jakob disease | \Prnptm3Lnq/\Prnptm3Lnq | involves: 129P2/OlaHsd * C57BL/6N | J:200974 | View | ||||
| Creutzfeldt-Jakob disease | \Tg(Prnp*)#Rgab/0 | involves: C57BL/6 * FVB/N | J:183170 | View | ||||
| Creutzfeldt-Jakob disease | \Tg(Prnp*D177N*M128V)A21Rchi/0 | involves: C57BL/6 * CBA | J:142098 | View | ||||
| Creutzfeldt-Jakob disease | \Tg(Prnp*D177N*M128V)A21Rchi/\Tg(Prnp*D177N*M128V)A21Rchi | involves: C57BL/6 * CBA | J:142098 | View | ||||
| fatal familial insomnia | \Prnptm2Lnq/\Prnptm2Lnq | involves: 129P2/OlaHsd * C57BL/6N | J:154937, J:200974 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(Prnp*A116V*M128V)1309Jama/0 |
involves: 129S7/SvEvBrd | J:151934 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(Prnp*P101L)2866Sbp/0 |
involves: 129S7/SvEvBrd * FVB/N | J:136434 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(Prnp*P101L)2866Sbp/\Tg(Prnp*P101L)2866Sbp |
involves: 129S7/SvEvBrd * FVB/N | J:136434 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Tg(Prnp*P101L)174Sbp/0 | involves: C57BL/6 * SJL | J:127373 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Tg(Prnp*P101L)2247Sbp/0 | involves: FVB/N | J:136434 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Tg(Prnp*P101L)2862Sbp/0 | involves: FVB/N | J:136434 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Tg(Prnp*P101L)2866Sbp/0 | involves: FVB/N | J:136434 | View | ||||
| malaria | \Fcgr2btm1Ttk/\Fcgr2btm1Ttk | C.129S4-Fcgr2btm1Ttk | J:120905 | View | ||||
| malaria | \Icam1tm1Bay/\Icam1tm1Bay | B6.129S7-Icam1tm1Bay/J | J:193592 | View | ||||
| malaria | \Pklrchar4/\Pklrchar4 | involves: A/J * C57BL/6 | J:86735, J:141722 | View | ||||
| Middle East respiratory syndrome | \Dpp4em1Rba/\Dpp4+ | C57BL/6J-Dpp4em1Rba | J:279834 | View | ||||
| Middle East respiratory syndrome | \Dpp4em1Rba/\Dpp4em1Rba | C57BL/6J-Dpp4em1Rba | J:279834, J:279723 | View | ||||
| Middle East respiratory syndrome | \Dpp4tm1(DPP4)Vlcg/? | involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac | J:238079 | View | ||||
| Middle East respiratory syndrome | \Dpp4tm1(DPP4)Vlcg/? | involves: 129S6/SvEvTac * C57BL/6NTac | J:223728 | View | ||||
| Middle East respiratory syndrome | \Dpp4tm1.1(DPP4)Pbmj/\Dpp4tm1.1(DPP4)Pbmj | involves: C57BL/6 * C57BL/6NTac | J:242025 | View | ||||
| | chronic recurrent multifocal osteomyelitis | \Pstpip2cmo/\Pstpip2cmo | C.Cg-Pstpip2cmo/J | J:105410, J:104476 | View | |||
| Coronavirus infectious disease | \Ccr1tm1Gao/\Ccr1tm1Gao | B6.129S4-Ccr1tm1Gao | J:162707 | View | ||||
| Coronavirus infectious disease | \Ccr2tm1Mae/\Ccr2tm1Mae | B6.129P2-Ccr2tm1Mae | J:162707 | View | ||||
| Coronavirus infectious disease | \Ccr5tm1Kuz/\Ccr5tm1Kuz | B6.129P2-Ccr5tm1Kuz | J:162707 | View | ||||
| Coronavirus infectious disease | \EgfrMhdadsk5/\Egfr+ | involves: 129S1/SvImJ * C3HeB/FeJ | J:243599 | View | ||||
| Coronavirus infectious disease | \Muc4tm1Unc/\Muc4tm1Unc | B6NTac.129(FVB)-Muc4tm1Unc/Rand | J:287566 | View | ||||
| Coronavirus infectious disease | \Myd88tm1Aki/\Myd88tm1Aki | B6.129P2-Myd88tm1Aki | J:162707 | View | ||||
| Coronavirus infectious disease | \Ppp1r14ctm1Uhl/\Ppp1r14ctm1Uhl | B6;129S6-Ppp1r14ctm1Uhl/J | J:288523 | View | ||||
| Coronavirus infectious disease | \Serpine1tm1Mlg/\Serpine1tm1Mlg | B6.129S2-Serpine1tm1Mlg/J | J:288556 | View | ||||
| Coronavirus infectious disease | \Ticam2tm1Aki/\Ticam2tm1Aki | involves: C57BL/6 | J:270045 | View | ||||
| HTLV-1-associated myelopathy/tropical spastic paraparesis | \Zeb1tm1Yhi/\Zeb1tm1Yhi | either: (involves: 129 * C3H * C57BL/6) or (involves: 129 * C57BL/6 * ICR) | J:139194 | View | ||||
| malaria | \Ank1MRI23420/\Ank1MRI23420 | SJL/J-Ank1MRI23420 | J:187820 | View | ||||
| malaria | \Ank1nb/\Ank1nb | involves: C57BL/6J * WB/Re | J:111131 | View | ||||
| malaria | \Aqp4tm1.1Lmno/\Aqp4tm1.1Lmno | B6.Cg-Aqp4tm1.1Lmno | J:193622 | View | ||||
| malaria | \Hmox1tm1Mlee/\Hmox1tm1Mlee | involves: 129S2/SvPas * BALB/c | J:153083 | View | ||||
| malaria | \Ifngtm1Ts/\Ifngtm1Ts | involves: 129S7/SvEvBrd * C57BL/6 | J:189794 | View | ||||
| severe acute respiratory syndrome | \Stat1tm1Rds/\Stat1tm1Rds | 129S6/SvEv-Stat1tm1Rds/Tac | J:286237 | View | ||||
| viral infectious disease | \Cebpbtm1Vpo/\Cebpbtm1Vpo | involves: 129S/SvEv * MF1 | J:25215 | View | ||||
| | Zika fever | \Stat2tm1.1(STAT2)Diam/\Stat2tm1.1(STAT2)Diam | C57BL/6-Stat2tm1.1(STAT2)Diam | J:261503 | View | |||
| Transgenes and Other Mutations | acquired immunodeficiency syndrome | \Tg(HIV)26Aln/0 | involves: FVB/N | J:84552 | View | |||
| Coronavirus infectious disease | \Tg(FOXJ1-ACE2)1Rba/0 | involves: C3H * C57BL/6 | J:287092 | View | ||||
| COVID-19 | \Tg(Ace2-ACE2)1Cqin/0 | involves: ICR | J:287631, J:288244 | View | ||||
| COVID-19 | \Tg(FOXJ1-ACE2)1Rba/0 | involves: C3H * C57BL/6 | J:288386 | View | ||||
| COVID-19 | \Tg(K18-ACE2)2Prlmn/0 | B6.Cg-Tg(K18-ACE2)2Prlmn/J | J:294084, J:296067, J:300960, J:302313 | View | ||||
| Kaposi's sarcoma | \Tg(Acta2-RAC1*G12V)33Pjgc/0 | involves: C57BL/6 * FVB/N | J:150015 | View | ||||
| Kaposi's sarcoma | \Tg(Acta2-RAC1*G12V)33Pjgc/\Tg(Acta2-RAC1*G12V)33Pjgc | involves: C57BL/6 * FVB/N | J:150015 | View | ||||
| Middle East respiratory syndrome | \Tg(CAG-DPP4)4Yuzh/0 | C57BL/6-Tg(CAG-DPP4)4Yuzh | J:286175 | View | ||||
| Middle East respiratory syndrome | \Tg(CAG-DPP4)52Ctkt/0 | involves: C3H/HeJ * C57BL/6J | J:227925, J:258199 | View | ||||
| Middle East respiratory syndrome | \Tg(DPP4)2Nnag/0 | B6.Cg-Tg(DPP4)2Nnag | J:286321 | View | ||||
| Middle East respiratory syndrome | \Tg(KRT18-DPP4)3Pbmj/0 | involves: C57BL/6J * SJL/J | J:285467, J:286231 | View | ||||
| Middle East respiratory syndrome | \Tg(Tk1-DPP4)27Ysj/0 | involves: C57BL/6 * FVB/N | J:290259 | View | ||||
| severe acute respiratory syndrome | \Tg(Ace2-ACE2)1Cqin/0 | involves: ICR | J:141460 | View | ||||
| severe acute respiratory syndrome | \Tg(CAG-ACE2)AC70Ctkt/0 | either: (involves: BALB/c * C3H/HeJ * C57BL/6J) or (involves: C3H/HeJ * C57BL/6 * C57BL/6J) | J:117824 | View | ||||
| severe acute respiratory syndrome | \Tg(FOXJ1-ACE2)1Rba/0 | involves: C3H * C57BL/6 | J:287092 | View | ||||
| severe acute respiratory syndrome | \Tg(K18-ACE2)2Prlmn/0 | involves: C57BL/6J * SJL/J | J:283648 | View | ||||
| viral infectious disease | \Tg(H2-K-IL6)2Srj/0 | B6.Cg-Tg(H2-K-IL6)2Srj | J:185153 | View | ||||
| Additional Complex Models | Coronavirus infectious disease |
\Stat1tm1Dlv/\Stat1tm1Dlv \Tg(ANPEP)270Mmul/\Tg(ANPEP)270Mmul |
involves: 129S/SvEv * ICR | J:99728 | View | |||
| Coronavirus infectious disease |
\Stat1tm1Dlv/\Stat1tm1Dlv \Tg(ANPEP)861Mmul/\Tg(ANPEP)861Mmul |
involves: 129S/SvEv * ICR | J:99728 | View | ||||
| measles |
\Ifnar1tm1Agt/\Ifnar1tm1Agt \Tg(CD46)373Zbz/\Tg(CD46)373Zbz |
involves: 129S2/SvPas * C3H/He * C57BL/6 | J:160878 | View | ||||
| Middle East respiratory syndrome | \Gt(ROSA)26Sorem1(DPP4)Yowa/\Gt(ROSA)26Sorem1(DPP4)Yowa | C57BL/6-Gt(ROSA)26Sorem1(DPP4)Yowa | J:279060 | View | ||||
| prion disease | \Prnpem2.1(Prnp*D178N)Jwat/\Prnpem2.1(Prnp*D178N)Jwat | involves: 129S4/SvJae * C57BL/6 | J:361333 | View | ||||
| prion disease | \Prnpem3.1(Prnp*E200K)Jwat/\Prnpem3.1(Prnp*E200K)Jwat | involves: 129S4/SvJae * C57BL/6 | J:361333 | View | ||||
| variant Creutzfeldt-Jakob disease |
\Prnptm1Cwe/\Prnptm1Cwe \Tg(PRNP)23454Sbp/0 |
involves: 129S7/SvEvBrd * FVB/N | J:236012 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Creutzfeldt-Jakob disease | \Prnptm1Cwe/\Prnptm1Cwe | involves: 129S7/SvEvBrd * C57BL/6 | J:472 | View | |||
| Creutzfeldt-Jakob disease | \Prnptm1Edin/\Prnptm1Edin | 129P2/OlaHsd-Prnptm1Edin/EdinH | J:58820 | View | ||||
| Creutzfeldt-Jakob disease | \Prnptm1Miy/\Prnptm1Miy | involves: 129S4/SvJae * C57BL/6 | J:69186 | View | ||||
| Creutzfeldt-Jakob disease | \Prnptm1Rcm/\Prnptm1Rcm | 129P2/OlaHsd-Prnptm1Rcm | J:45908 | View | ||||
| fatal familial insomnia | \Prnptm1Edin/\Prnptm1Edin | 129P2/OlaHsd-Prnptm1Edin/EdinH | J:58820 | View | ||||
| fatal familial insomnia | \Prnptm1Rcm/\Prnptm1Rcm | 129P2/OlaHsd-Prnptm1Rcm | J:45908 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Prnptm1Cwe/\Prnptm1Cwe | involves: 129S7/SvEvBrd * C57BL/6 | J:472 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Prnptm1Edin/\Prnptm1Edin | 129P2/OlaHsd-Prnptm1Edin/EdinH | J:58820 | View | ||||
| Gerstmann-Straussler-Scheinker syndrome | \Prnptm1Rcm/\Prnptm1Rcm | 129P2/OlaHsd-Prnptm1Rcm | J:45908 | View | ||||
| viral infectious disease |
\Il6tm1Kopf/\Il6tm1Kopf \Tg(H2-K-IL6)2Srj/0 |
involves: 129S2/SvPas * C57BL/6 * DBA/2 | J:185153 | View | ||||