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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pax3
paired box 3
MGI:97487
201 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
a/a
Pax3Sp-1H/Pax3Sp-1H
involves: 101/H * C3H/HeH * C57BL/6
abnormal cerebral cortex morphology J:19818
abnormal lateral ventricle morphology J:19818
absent choroid plexus J:19818
absent olfactory bulb J:19818
exencephaly J:19818
incomplete rostral neuropore closure J:19818
Arl13bhnn/Arl13btm1Tc
Pax3tm1(cre)Joe/Pax3+
involves: 129S6/SvEvTac * C57BL/6J
decreased body size J:173637
perinatal lethality, incomplete penetrance J:173637
postnatal lethality, complete penetrance J:173637
respiratory distress J:173637
Bcortm1.1Vjba/Y
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * C57BL/6J
abnormal major salivary gland morphology J:296645
abnormal tongue morphology J:296645
abnormal tongue position J:296645
absent gastric milk in neonates J:296645
bifid tongue J:296645
normal cardiovascular system phenotype J:296645
complete cleft palate J:296645
decreased tympanic ring size J:296645
failure of palatal shelf elevation J:296645
neonatal lethality, complete penetrance J:296645
pallor J:296645
short mandible J:296645
short Meckel's cartilage J:296645
tongue ankylosis J:296645
Cdkn2atm4Rdp/Cdkn2atm4Rdp
Myf6tm1(cre)Mrc/Myf6+
Pax3tm1Mrc/Pax3tm1Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
increased rhabdomyosarcoma incidence J:93444
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Pax3tm1(cre)Joe/Pax3+
Not Specified
abnormal neural tube morphology J:96431
Dkk1tm1.1Svo/Dkk1tm1.2Svo
Pax3tm1(cre)Joe/Pax3+
involves: 129P2/OlaHsd * C57BL/6 * SJL
abnormal craniofacial development J:173125
caudal body truncation J:173125
perinatal lethality, complete penetrance J:173125
normal renal/urinary system phenotype J:173125
Egln1tm2.1Fsl/Egln1+
Pax3tm1(cre)Joe/Pax3+
involves: 129 * C57BL/6
increased hematocrit J:202737
polycythemia J:202737
Egln1tm2.1Fsl/Egln1tm2.1Fsl
Pax3tm1(cre)Joe/Pax3+
involves: 129 * C57BL/6
abnormal liver vasculature morphology J:202737
increased heart weight J:202737
increased hematocrit J:202737
increased liver weight J:202737
increased spleen weight J:202737
polycythemia J:202737
Elmo1tm1.2Ravi/Elmo1tm1.2Ravi
Elmo2tm1c(EUCOMM)Hmgu/Elmo2tm1c(EUCOMM)Hmgu
Pax3tm1(cre)Joe/Pax3+
involves: 129P2/OlaHsd * C57BL/6N
abnormal diaphragm development J:331473
abnormal muscle development J:331473
lethality during fetal growth through weaning, complete penetrance J:331473
Elmo2tm1c(EUCOMM)Hmgu/Elmo2tm1c(EUCOMM)Hmgu
Pax3tm1(cre)Joe/Pax3+
involves: 129 * C57BL/6N
preweaning lethality, incomplete penetrance J:331473
Ets1tm1Most/Ets1tm1Most
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
double outlet right ventricle J:334073
Ets1tm2Jml/Ets1tm2Jml
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCrl
abnormal cardiac neural crest cell migration J:334073
abnormal cardiac outflow tract development J:334073
abnormal conotruncal ridge morphology J:334073
abnormal neural crest cell physiology J:334073
double outlet right ventricle J:334073
Fat1tm1Fhel/Fat1tm1Fhel
Pax3tm1(cre)Joe/Pax3+
Tg(Myl1-lacZ)1Ibdml/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
abnormal muscle development J:199157
abnormal skeletal muscle morphology J:199157
ectopic skeletal muscle J:199157
Fignfi/Fignfi
Pax3Sp/Pax3Sp
BR.Cg-Pax3Sp Fignfi
open neural tube J:11996
prenatal lethality, complete penetrance J:11996
Foxo1tm1Mrc/Foxo1tm1Mrc
Myf6tm1(cre)Mrc/Myf6+
Pax3tm1Mrc/Pax3tm1Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
normal neoplasm J:93444
Gata4tm1.1Sad/Gata4tm1.2Sad
Pax3Sp-d/Pax3Sp-d
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
normal muscle phenotype J:231793
normal respiratory system phenotype J:231793
Gata4tm1.1Sad/Gata4tm1.2Sad
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
normal muscle phenotype J:231793
Gt(ROSA)26Sortm1(en/Cdx1,-EGFP)Npln/Gt(ROSA)26Sor+
Pax3Sp/Pax3+
Tg(Pax3-cre)1Joe/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
abnormal coat/hair pigmentation J:231654
abnormal enteric ganglia morphology J:231654
abnormal tail hair pigmentation J:231654
belly spot J:231654
Gt(ROSA)26Sortm1(MAML1)Wsp/Gt(ROSA)26Sor+
Pax3tm1(cre)Joe/Pax3+
Not Specified
abnormal neural tube morphology J:130251
decreased neuronal precursor cell number J:130251
loss of glutamate neurons J:130251
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Pax3Sp-d/Pax3Sp-d
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * C57BL/6J * SJL/J
abnormal diaphragm morphology J:231793
Gt(ROSA)26Sortm2(SS18)Mrc/Gt(ROSA)26Sortm2(SS18)Mrc
Pax3tm1(cre)Joe/Pax3tm1(cre)Joe
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
embryonic lethality during organogenesis, complete penetrance J:120967
Gt(ROSA)26Sortm3(SS18/EGFP)Mrc/Gt(ROSA)26Sortm3(SS18/EGFP)Mrc
Pax3tm1(cre)Joe/Pax3tm1(cre)Joe
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
embryonic lethality during organogenesis, complete penetrance J:120967
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Pax3tm1(cre)Joe/Pax3+
involves: C57BL/6
embryonic lethality, complete penetrance J:194308
Itm2atm1.1Buck/Y
Pax3tm1(cre)Joe/Pax3+
involves: C57BL/6
no abnormal phenotype detected J:200546
Itm2atm1.1Buck/Y
Pax3tm1(cre)Joe/Pax3tm1(cre)Joe
involves: C57BL/6
abnormal neural tube morphology J:200546
Itm2atm1.2Buck/Y
Pax3tm4Buck/Pax3tm4Buck
involves: C57BL/6
abnormal neural tube morphology J:200546
KitWps/Kit+
Pax3Sp-1Wli/Pax3+
involves: C57BL/6J * CBA/CaJ
belly spot J:196572
white spotting J:196572
Lbx1tm1Thbr/Lbx1tm1Thbr
Pax3Sp-1H/Pax3Sp-1H
involves: 101/H * 129S4/SvJae * C3H/HeH * C57BL/6
open neural tube J:78622
Lbx2tm1Fchn/Lbx2tm1Fchn
Pax3Sp/Pax3Sp
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal cranial ganglia morphology J:121890
abnormal dorsal root ganglion morphology J:121890
edema J:121890
exencephaly J:121890
open neural tube J:121890
Men1tm1.2Ctre/Men1+
Pax3tm1(cre)Joe/Pax3+
involves: 129S6/SvEvTac
no abnormal phenotype detected J:127545
Men1tm1.2Ctre/Men1tm1.2Ctre
Pax3tm1(cre)Joe/Pax3+
involves: 129S6/SvEvTac
abnormal basisphenoid bone morphology J:127545
abnormal palatal mesenchymal cell differentiation J:127545
abnormal palatal mesenchymal cell proliferation J:127545
abnormal palatal shelf bone ossification J:127545
abnormal pterygoid process morphology J:127545
abnormal rib development J:127545
abnormal rib morphology J:127545
abnormal secondary palate development J:127545
abnormal snout morphology J:127545
abnormal sternum morphology J:127545
abnormal sternum ossification J:127545
absent gastric milk in neonates J:127545
bilateral cleft palate J:127545
cleft secondary palate J:127545
cyanosis J:127545
meteorism J:127545
palatal shelf hypoplasia J:127545
palatal shelves fail to meet at midline J:127545
perinatal lethality, complete penetrance J:127545
primary atelectasis J:127545
respiratory distress J:127545
rib bifurcation J:127545
rib fusion J:127545
short snout J:127545
short soft palate J:127545
Men1tm1.2Ctre/Men1tm1.2Ctre
Pax3tm1(cre)Joe/Pax3+
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
involves: 129S4/SvJaeSor * 129S6/SvEvTac
normal cardiovascular system phenotype J:127545
normal digestive/alimentary phenotype J:127545
Mettm1Cpo/Met+
Pax3tm2.1(PAX3/FOXO1A)Buck/Pax3+
involves: 129 * BALB/c * C57BL/6
normal embryo phenotype J:86911
Mettm1Cpo/Mettm1Cpo
Pax3tm2.1(PAX3/FOXO1A)Buck/Pax3+
involves: 129 * BALB/c * C57BL/6
normal embryo phenotype J:86911
Myf6tm1(cre)Mrc/Myf6+
Pax3tm1Mrc/Pax3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
increased rhabdomyosarcoma incidence J:93444
Myf6tm1(cre)Mrc/Myf6+
Pax3tm1Mrc/Pax3tm1Mrc
Trp53tm1Brn/Trp53+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
increased rhabdomyosarcoma incidence J:93444
Myf6tm1(cre)Mrc/Myf6+
Pax3tm1Mrc/Pax3tm1Mrc
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
increased rhabdomyosarcoma incidence J:93444
Myh3tm1.2Sajm/Myh3tm1.1Sajm
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J
abnormal muscle precursor cell morphology J:287755
Nf1tm1Fcr/Nf1tm1Par
Pax3tm1(cre)Joe/Pax3+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
abnormal somatic sensory system morphology J:114455
adrenal medulla hyperplasia J:114455
neonatal lethality, complete penetrance J:114455
Notch2tm3Grid/Notch2tm3.1Grid
Pax3tm1(cre)Joe/Pax3+
involves: 129 * C57BL/6
abnormal tooth morphology J:132939
abnormal vascular smooth muscle morphology J:132939
aorta stenosis J:132939
cyanosis J:132939
decreased body weight J:132939
postnatal lethality, incomplete penetrance J:132939
pulmonary artery stenosis J:132939
supravalvar pulmonary trunk stenosis J:132939
Nr2c2tm1Bbm/Nr2c2tm1Bbm
Pax3tm1(cre)Joe/Pax3+
Not Specified
abnormal mechanical nociception J:197895
decreased neuron number J:197895
decreased pruritus J:197895
increased chemical nociceptive threshold J:197895
increased thermal nociceptive threshold J:197895
Pax3Sp-4H/Pax3+
involves: 101/H * C3H/HeH
belly spot J:4295
prenatal lethality, incomplete penetrance J:4295
variable body spotting J:4295
Pax3Sp-4H/Pax3Sp-4H
involves: 101/H * C3H/HeH
embryonic lethality between implantation and somite formation, complete penetrance J:33375
failure to gastrulate J:33375
Pax3Sp/Pax3Sp
Trp53tm1Tyj/Trp53+
involves: 129S2/SvPas * C57BL * C57BL/6J * FVB
open neural tube J:75569
Pax3Sp/Pax3Sp
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL * C57BL/6J * FVB
normal nervous system phenotype J:75569
Pax3tm1(cre)Joe/Pax3+
Tbx5tm1Jse/Tbx5tm1Jse
Not Specified
normal limbs/digits/tail phenotype J:157917
Pax3tm1(cre)Joe/Pax3+
Rbpjtm1Hon/Rbpjtm1Hon
involves: 129P2/OlaHsd
abnormal diaphragm morphology J:120053
abnormal dorsal interneuron 4 morphology J:130251
abnormal epaxial muscle morphology J:120053
abnormal glutaminergic neuron morphology J:130251
abnormal intercostal muscle morphology J:120053
abnormal myogenesis J:120053
abnormal neural tube morphology J:130251
abnormal neuron differentiation J:130251
decreased neuronal precursor cell number J:130251
decreased satellite cell number J:120053
hypaxial muscle hypoplasia J:120053
loss of GABAergic neurons J:130251
neonatal lethality, complete penetrance J:120053
no spontaneous movement J:120053
respiratory failure J:120053
Pax3tm1(cre)Joe/Pax3+
Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
Not Specified
normal cardiovascular system phenotype J:143444
short mandible J:143444
short snout J:143444
Pax3tm1(FOXO1A)Gcg/Pax3+
either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * NMRI)
abnormal diaphragm development J:79365
abnormal interventricular septum morphology J:79365
abnormal neural tube morphology J:79365
abnormal pulmonary alveolus morphology J:79365
abnormal skeletal muscle morphology J:79365
abnormal thymus lobule morphology J:79365
abnormal tongue muscle morphology J:79365
abnormal vena cava morphology J:79365
normal cardiovascular system phenotype J:79365
congestive heart failure J:79365
cyanosis J:79365
dilated pulmonary trunk J:79365
ectopic thymus J:79365
exencephaly J:79365
muscular ventricular septal defect J:79365
neonatal lethality, incomplete penetrance J:79365
normal neoplasm J:79365
patent tricuspid valve J:79365
respiratory distress J:79365
spina bifida J:79365
thick interventricular septum J:79365
thin ventricular wall J:79365
Pax3tm1.1Sjc/Pax3tm1.1Sjc
Pax7tm1.2Fan/Pax7tm1.2Fan
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129 * C57BL/6 * CBA * SJL
normal muscle phenotype J:150962
Pax3tm1Buck/Pax3tm1Buck
Pax7tm2Pgr/Pax7tm2Pgr
either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ) or (involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal myotome development J:99365
prenatal lethality, complete penetrance J:99365
Pax3tm1Mrc/Pax3+
Tg(CMV-cre)1Cgn/?
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
abnormal cerebral cortex morphology J:93443
abnormal forebrain morphology J:93443
abnormal nasal bone morphology J:93443
abnormal sternum morphology J:93443
absent frontal bone J:93443
absent interparietal bone J:93443
absent olfactory bulb J:93443
absent parietal bone J:93443
absent premaxilla J:93443
anophthalmia J:93443
cranioschisis J:93443
exencephaly J:93443
forebrain hypoplasia J:93443
hypaxial muscle hypoplasia J:93443
maxilla hypoplasia J:93443
midbrain hyperplasia J:93443
omphalocele J:93443
optic placode degeneration J:93443
rib fusion J:93443
small dorsal root ganglion J:93443
thin diaphragm muscle J:93443
vertebral fusion J:93443
Pax3tm1Mrc/Pax3+
Pax7tm1(cre)Mrc/Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal nose morphology J:93443
abnormal premaxilla morphology J:93443
decreased body weight J:93443
decreased satellite cell number J:93443
decreased skeletal muscle fiber diameter J:93443
decreased skeletal muscle mass J:93443
increased skeletal muscle fiber density J:93443
lacrimal bone hypoplasia J:93443
maxilla hypoplasia J:93443
muscle hypoplasia J:93443
normal neoplasm J:93443
postnatal growth retardation J:93443
premature death J:93443
turbinate hypoplasia J:93443
Pax3tm1Mrc/Pax3tm1Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:93444
Pax3tm3.1(Pax7)Buck/Pax3Sp
involves: 129S2/SvPas
abnormal diaphragm development J:90568
abnormal myogenesis J:90568
decreased cell proliferation J:90568
normal integument phenotype J:90568
perinatal lethality, complete penetrance J:90568
spina bifida J:90568
Pax3tm3.1(Pax7)Buck/Pax3tm3.1(Pax7)Buck
involves: 129S2/SvPas
abnormal diaphragm development J:90568
abnormal muscle development J:176192
abnormal muscle precursor cell migration J:90568
abnormal myogenesis J:90568
decreased cell proliferation J:90568
normal embryo phenotype J:176192
normal integument phenotype J:90568
normal nervous system phenotype J:90568
perinatal lethality, complete penetrance J:90568
Pax3tm5Buck/Pax3+
involves: 129S2/SvPas
belly spot J:112275
Pax3tm6(Pax8)Buck/Pax3+
involves: 129S2/SvPas
abnormal muscle development J:176192
abnormal myotome development J:176192
belly spot J:176192
Pax3tm6(Pax8)Buck/Pax3tm6(Pax8)Buck
involves: 129S2/SvPas
abnormal neural crest cell migration J:176192
absent dorsal root ganglion J:176192
absent skeletal muscle J:176192
open neural tube J:176192
Pax3tm6.1(Pax8)Buck/Pax3+
involves: 129S2/SvPas * BALB/c * C57BL/6
abnormal muscle development J:176192
abnormal myotome development J:176192
belly spot J:176192
Pax3tm6.1(Pax8)Buck/Pax3tm6.1(Pax8)Buck
involves: 129S2/SvPas * BALB/c * C57BL/6
abnormal dermomyotome development J:176192
abnormal dorsal root ganglion morphology J:176192
abnormal muscle development J:176192
abnormal muscle precursor cell migration J:176192
abnormal myotome development J:176192
abnormal neural crest cell migration J:176192
abnormal neural tube morphology J:176192
abnormal somite development J:176192
absent skeletal muscle J:176192
exencephaly J:176192
lethality throughout fetal growth and development, complete penetrance J:176192
spina bifida J:176192
Pax3tm6.1(Pax8)Buck/Pax3tm6.2Buck
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
abnormal muscle development J:176192
abnormal neural tube morphology J:176192
Rbfox2tm1.1Dblk/Rbfox2tm1.1Dblk
Pax3tm1(cre)Joe/0
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J
abnormal axial skeleton morphology J:279139
abnormal craniofacial bone morphology J:279139
abnormal craniofacial morphology J:279139
abnormal frontal bone morphology J:279139
abnormal hypoglossal nerve morphology J:279139
abnormal nasal bone morphology J:279139
abnormal neurocranium morphology J:279139
abnormal oculomotor nerve morphology J:279139
abnormal palatal mesenchymal cell proliferation J:279139
abnormal rostral-caudal body axis extension J:279139
abnormal spine curvature J:279139
abnormal trochlear nerve morphology J:279139
absent palatine bone horizontal plate J:279139
atelectasis J:279139
normal cardiovascular system phenotype J:279139
cleft secondary palate J:279139
decreased bone ossification J:279139
ectopic bone J:279139
normal endocrine/exocrine gland phenotype J:279139
frontal bone hypoplasia J:279139
fusion of vertebral bodies J:279139
normal muscle phenotype J:279139
neonatal lethality, complete penetrance J:279139
palatal shelves fail to meet at midline J:279139
respiratory distress J:279139
respiratory failure J:279139
small mandible J:279139
small thoracic cavity J:279139
subcutaneous edema J:279139
thin dermal layer J:279139
Rbfox2tm1.1Dblk/Rbfox2tm1.1Dblk
Pax3tm1(cre)Joe/0
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J
normal cellular phenotype J:279139
normal embryo phenotype J:279139
Sp8tm1Smb/Sp8tm2Smb
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129X1/SvJ
abnormal face development J:200761
absent frontal bone J:200761
absent parietal bone J:200761
cleft palate J:200761
cleft upper lip J:200761
normal craniofacial phenotype J:200761
exencephaly J:200761
midline facial cleft J:200761
ocular hypertelorism J:200761
small snout J:200761

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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory