Pax7^tm1.2Fan
Targeted Allele Detail

Summary

• Symbol: Pax7^tm1.2Fan
• Name: paired box 7; targeted mutation 1.2, Chen-Ming Fan
• MGI ID: MGI:4353152
• Synonyms: Pax7^delta
• Gene: Pax7 Location: Chr4:139464373-139560839 bp, - strand Genetic Position: Chr4, 70.83 cM
• Alliance: Pax7^tm1.2Fan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150962
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removes exon 2. The absence of protein expression was confirmed by western blot analysis on P10 tibialis anterior muscle extracts. (J:150962)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax7 Mutation: 39 strains or lines available

References

• Original: J:150962 Lepper C, et al., Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements. Nature. 2009 Jul 30;460(7255):627-31
• All: 3 reference(s)