Arl13bhnn
Chemically induced Allele Detail
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Symbol: |
Arl13bhnn |
Name: |
ADP-ribosylation factor-like 13B; hennin |
MGI ID: |
MGI:3578151 |
Gene: |
Arl13b Location: Chr16:62614048-62667403 bp, - strand Genetic Position: Chr16, 36.43 cM, cytoband C1.2
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Alliance: |
Arl13bhnn page
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Allele Type: |
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Chemically induced (ENU) |
Mutation: |
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Single point mutation
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Mutation details: This mutation was discovered in a screen of G3 progeny of N-ethyl, N-nitrosourea-treated male mice for morphological defects at embryonic day (e) 9.5. It has been identified as a T-o-G transversion (GRCm39:chr16:62651104A>C) in the splice donor sequence of exon 2 which has been shown by RT-PCR to result in exclusion of this exon from mature transcripts and thus of most of a putative GTPase domain, including four consensus nucleotide binding sites, from the encoded protein. Immunoblot analysis reveals the absence of either normally-present protein isoform in mutant embryos.
(J:120712)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Arl13b Mutation: |
22 strains or lines available
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Original: |
J:98216 Garcia-Garcia MJ, et al., Inaugural Article: Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5913-9 |
All: |
15 reference(s) |
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