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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arl13bhnn
hennin
MGI:3578151
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Arl13bhnn/Arl13bhnn involves: C3HeB/FeJ * C57BL/6J MGI:3580673
hm2
 		Arl13bhnn/Arl13bhnn involves: C57BL/6J MGI:5052338
cn3
 		Arl13bhnn/Arl13btm1Tc
Pax3tm1(cre)Joe/Pax3+ 		involves: 129S6/SvEvTac * C57BL/6J MGI:5052337


Genotype
MGI:3580673
hm1
Allelic
Composition		 Arl13bhnn/Arl13bhnn
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arl13bhnn mutation (0 available); any Arl13b mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
abnormal left-right axis patterning ( J:98216 )
• left-right randomization
absent floor plate ( J:98216 )
• no floor plate in the caudal spinal cord

nervous system
absent floor plate ( J:98216 )
• no floor plate in the caudal spinal cord




Genotype
MGI:5052338
hm2
Allelic
Composition		 Arl13bhnn/Arl13bhnn
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arl13bhnn mutation (0 available); any Arl13b mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
spina bifida ( J:173637 )
• moderate spina bifida in the caudal neural tube

nervous system
spina bifida ( J:173637 )
• moderate spina bifida in the caudal neural tube




Genotype
MGI:5052337
cn3
Allelic
Composition		 Arl13bhnn/Arl13btm1Tc
Pax3tm1(cre)Joe/Pax3+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arl13bhnn mutation (0 available); any Arl13b mutation (22 available)
Arl13btm1Tc mutation (0 available); any Arl13b mutation (22 available)
Pax3tm1(cre)Joe mutation (1 available); any Pax3 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, incomplete penetrance ( J:173637 )
• all but one mouse dies at birth after an episode of gasping unlike wild-type mice
postnatal lethality, complete penetrance ( J:173637 )
• one surviving mouse died by P21

respiratory system
respiratory distress ( J:173637 )
• all but one mouse dies at birth after an episode of gasping unlike wild-type mice

growth/size/body
decreased body size ( J:173637 )
• one surviving mouse




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory