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All mouse models of dermatitis with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | atopic dermatitis |
\Tg(KRT5-tTA)1216Glk/0 \Tg(tetO-Il13)1Tazh/0 |
B6.Cg-Tg(KRT5-tTA)1216Glk Tg(tetO-Il13)1Tazh | J:150232 | View | |||
| atopic dermatitis | \Tg(KRT14-Il4)#Lsch/0 | involves: BALB/cBy * C57BL/6 | J:126285 | View | ||||
| atopic dermatitis | \Tg(KRT14-Il18)#Knak/0 | C57BL/6-Tg(KRT14-Il18)#Knak | J:78602 | View | ||||
| epidermolysis bullosa simplex | \Krt14tm1Der/\Krt14tm1Der | involves: 129X1/SvJ | J:67320 | View | ||||
| epidermolysis bullosa simplex | \Krt14tm1Efu/\Krt14tm1Efu | involves: 129 | J:25763 | View | ||||
| epidermolysis bullosa simplex Ogna type | \Plectm1Gwi/\Plectm1Gwi | involves: 129S1/Sv * 129X1/SvJ | J:59000 | View | ||||
| epidermolysis bullosa simplex Ogna type | \Plectm2Gwi/\Plectm2Gwi | involves: 129S1/Sv * 129X1/SvJ | J:59000 | View | ||||
| epidermolysis bullosa simplex Ogna type | \Plectm7.1Gwi/\Plec+ | involves: 129P2/OlaHsd * C57BL/6 | J:179812 | View | ||||
| epidermolysis bullosa simplex Ogna type | \Plectm7.1Gwi/\Plectm7.1Gwi | involves: 129P2/OlaHsd * C57BL/6 | J:179812 | View | ||||
| junctional epidermolysis bullosa |
\Col17a1em1Dcr/\Col17a1em1Dcr \Lamc2jeb/\Lamc2jeb |
B6.Cg-Lamc2jeb Col17a1em1Dcr/Dcr | J:352187 | View | ||||
| junctional epidermolysis bullosa |
\Col17a1em2Dcr/\Col17a1em2Dcr \Lamc2jeb/\Lamc2jeb |
C57BL/6J-Col17a1em2Dcr/Dcr | J:352187 | View | ||||
| junctional epidermolysis bullosa |
\Col17a1em8Dcr/\Col17a1+ \Lamc2jeb/\Lamc2jeb |
B6.Cg-Lamc2jeb Col17a1em8Dcr/Dcr | J:352187 | View | ||||
| junctional epidermolysis bullosa | \Col17a1em8Dcr/\Col17a1em8Dcr | C57BL/6J-Col17a1em8Dcr/DcrJ | J:352187 | View | ||||
| junctional epidermolysis bullosa |
\Lama3tm1Arte/\Lama3tm1Arte \Tg(KRT14-cre/ERT)20Efu/0 |
involves: C57BL/6 * CD-1 | J:240054 | View | ||||
| junctional epidermolysis bullosa with pyloric atresia | \Itgb4tm1Fgg/\Itgb4tm1Fgg | involves: 129S1/Sv * C57BL/6 | J:48924 | View | ||||
| | atopic dermatitis |
\Adam17tm1.2Bbl/\Adam17tm1.2Bbl \Sox9tm3(cre)Crm/\Sox9+ |
B6.129(SJL)-Sox9tm3(cre)Crm Adam17tm1.2Bbl | J:229771 | View | |||
| atopic dermatitis |
\Casp8tm1Hed/\Casp8tm1Hed \Tg(KRT14-cre)1Efu/0 |
Not Specified | J:167299 | View | ||||
| atopic dermatitis | \Ctsetm1Kjy/\Ctsetm1Kjy | involves: C57BL/6 | J:108745 | View | ||||
| atopic dermatitis | \Nfkbiatm1Stw/\Nfkbiatm1Stw | involves: 129S1/Sv | J:32527 | View | ||||
| atopic dermatitis | \Nfkbiztm1Mamo/\Nfkbiztm1Mamo | involves: 129S7/SvEvBrd | J:95040 | View | ||||
| atopic dermatitis | \Noa/\Noa+ | NOA | J:43274 | View | ||||
| atopic dermatitis | \Relbtm1Brv/\Relbtm1Brv | either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6) | J:63950 | View | ||||
| atopic dermatitis | \Sharpincpdm/\Sharpincpdm | C57BL/KaLawRij-Sharpincpdm | J:14539, J:31745, J:116833 | View | ||||
| atopic dermatitis |
\Tg(KRT5-rtTA)1Glk/0 \Tg(tetO/CMV-Tslp)#Sfz/0 |
involves: C3H * C57BL/6 * FVB/N | J:100506 | View | ||||
| atopic dermatitis | \Tmem79ma/\Tmem79ma | B6.CBACaGr-Tmem79ma/J | J:202453 | View | ||||
| atopic dermatitis | \Tmem79ma/\Tmem79ma | involves: C57BL/6JJcl * CBA/CaGr | J:202316 | View | ||||
| atopic dermatitis | \Traf3ip2adjm/\Traf3ip2adjm | A.KOR-Traf3ip2adjm | J:162859 | View | ||||
| atopic dermatitis | \Traf3ip2adjm/\Traf3ip2adjm | AK.KOR-Traf3ip2adjm | J:162859 | View | ||||
| atopic dermatitis | \Traf3ip2adjm/\Traf3ip2adjm | B6.KOR-Traf3ip2adjm | J:162859 | View | ||||
| atopic dermatitis | \Traf3ip2adjm/\Traf3ip2adjm | C.KOR-Traf3ip2adjm | J:162859 | View | ||||
| atopic dermatitis | \Traf3ip2adjm/\Traf3ip2adjm | KOR-Traf3ip2adjm | J:162859 | View | ||||
| atopic dermatitis | \Trpv3Nh/\Trpv3+ | involves: DS | J:42153 | View | ||||
| atopic dermatitis |
\Wasltm1.1Ttha/\Wasltm1.1Ttha \Tg(KRT14-cre)1Amc/0 |
involves: C57BL/6 * C57BL/6N * CBA | J:271857 | View | ||||
| atopic dermatitis 2 | \Flgft/\Flgft | STOCK a/a Tmem79ma Flgft/J | J:204304 | View | ||||
| epidermolysis bullosa simplex Dowling-Meara type | \Krt5tm1Tmm/\Krt5tm1Tmm | involves: 129P2/OlaHsd * BALB/c | J:76311 | View | ||||
| epidermolysis bullosa simplex Dowling-Meara type |
\Krt14tm1Der/\Krt14+ \Tg(KRT5-cre/PGR)1Der/? |
involves: 129X1/SvJ * FVB * ICR | J:67320 | View | ||||
| epidermolysis bullosa simplex Dowling-Meara type |
\Krt14tm1Der/\Krt14+ \Tg(KRT14-cre/PGR)1Der/? |
involves: 129X1/SvJ * FVB * ICR | J:67320 | View | ||||
| epidermolysis bullosa simplex Dowling-Meara type | \Krt14tm2Der/\Krt14+ | involves: 129X1/SvJ | J:67320 | View | ||||
| junctional epidermolysis bullosa Herlitz type | \Itga6tm1Egl/\Itga6tm1Egl | either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * C57BL/6 * CD-1) | J:33712 | View | ||||
| junctional epidermolysis bullosa Herlitz type | \Lamb3IAP/\Lamb3IAP | involves: C3H * C57BL/6 | J:42382 | View | ||||
| junctional epidermolysis bullosa Herlitz type | \Lamb3tm1.1Hosc/\Lamb3tm1.1Hosc | involves: 129S4/SvJae * C57BL/6 | J:218616 | View | ||||
| junctional epidermolysis bullosa Herlitz type | \Lamc2tm1Uit/\Lamc2tm1Uit | involves: C57BL/6 | J:85981 | View | ||||
| junctional epidermolysis bullosa non-Herlitz type | \Col17a1tm1Shzu/\Col17a1tm1Shzu | B6.129S-Col17a1tm1Shzu | J:121695 | View | ||||
| junctional epidermolysis bullosa non-Herlitz type | \Itgb4tm1Efu/\Itgb4tm1Efu | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:77644 | View | ||||
| junctional epidermolysis bullosa non-Herlitz type | \Lama3tm1Crt/\Lama3tm1Crt | involves: 129 * C57BL/6J | J:55865 | View | ||||
| junctional epidermolysis bullosa non-Herlitz type | \Lamb3IAP/\Lamb3IAP | involves: C3H * C57BL/6 | J:42382 | View | ||||
| junctional epidermolysis bullosa non-Herlitz type | \Lamc2jeb/\Lamc2jeb | 129X1/SvJ-Lamc2jeb | J:158873 | View | ||||
| pemphigus vulgaris | \Dsg3bal-Pas/\Dsg3bal-Pas | 129S2.Cg-Dsg3bal-Pas | J:46865 | View | ||||
| pemphigus vulgaris | \Dsg3bal/\Dsg3bal | C57BL/6J-Dsg3bal/J | J:42792 | View | ||||
| pemphigus vulgaris | \Dsg3tm1Stan/\Dsg3tm1Stan | involves: 129X1/SvJ * C57BL/6J | J:40804 | View | ||||
| recessive dystrophic epidermolysis bullosa | \Col7a1em#Jtol/\Col7a1em#Jtol | involves: 129S4/SvJae * BALB/c * C57BL/Ka * NOD | J:280214 | View | ||||
| recessive dystrophic epidermolysis bullosa | \Col7a1tm1Lbt/\Col7a1tm1Lbt | involves: 129S1/Sv * 129X1/SvJ * C57BL/6Crl | J:136145 | View | ||||
| recessive dystrophic epidermolysis bullosa | \Col7a1tm1Uit/\Col7a1tm1Uit | involves: 129S1/Sv | J:155326 | View | ||||
| recessive dystrophic epidermolysis bullosa | \Col7a1tm1Uit/\Col7a1tm1Uit | involves: 129S1/Sv * C57BL/6J | J:58533 | View | ||||
| recessive dystrophic epidermolysis bullosa |
\Col7a1tm1Uit/\Col7a1tm1Uit \Tg(KRT14-COL7A1*)1Shzu/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2 | J:155326 | View | ||||
| recessive dystrophic epidermolysis bullosa | \Grip1tm1Paw/\Grip1tm1Paw | involves: 129X1/SvJ * ICR | J:79476 | View | ||||
| | atopic dermatitis |
\Dock8tm1Ysfk/\Dock8tm1Ysfk \Tg(TcrAND)53Hed/0 |
involves: C57BL/6 * SJL | J:305132 | View | |||
| Transgenes and Other Mutations | atopic dermatitis | \Tg(APOC1)1Lmh/\Tg(APOC1)1Lmh | involves: C57BL/6 | J:135501 | View | |||
| atopic dermatitis | \Tg(CD2-Stat6*V625A*T626A)78Mhk/0 | involves: C3H * C57BL/6 | J:160119 | View | ||||
| atopic dermatitis | \Tg(KRT14-CASP1)1Miz/0 | involves: C57BL/6 | J:78602 | View | ||||
| atopic dermatitis | \Tg(KRT14-VP16/NR1I2)13Sdub/? | involves: C57BL/6 | J:258435 | View | ||||
| atopic dermatitis | \Tg(SV40-KLK7)1010Teg/0 | involves: C57BL/6J * CBA | J:75714 | View | ||||
| dermatitis | \Tg(KRT5-IKBKB)1Armz/0 | involves: C57BL/6 * DBA/2 | J:160072 | View | ||||
| dermatitis | \Tg(KRT5-IKBKB)2Armz/0 | involves: C57BL/6 * DBA/2 | J:160072 | View | ||||
| Additional Complex Models | atopic dermatitis |
\Fgfr1tm1Upir/\Fgfr1tm1Upir \Fgfr2tm1Dor/\Fgfr2tm1Dor \Tg(KRT5-cre)5132Jlj/0 |
involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J | J:221184 | View | |||
| bullous pemphigoid | \Col17a1tm1.1(COL17A1)Zliu/\Col17a1tm1.1(COL17A1)Zliu | involves: 129P2/OlaHsd * C57BL/6J | J:261781 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Hailey-Hailey disease | \Atp2c1tm1Ges/\Atp2c1+ | involves: 129X1/SvJ * Black Swiss | J:124662 | View | |||