Analysis Tools
integument
blistering
(
J:67320
)
|
• after application of a topical antiprogestin, RU486, to the forelimbs and chest of newborn pups so that the cre transgene translocates from the cytoplasm to the nucleus of epidermal cells and becomes active, mice developed blisters filled with fluid on the front legs and paws
• blistering occurs within the basal layer of the epidermis
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| generalized severe epidermolysis bullosa simplex 1A | DOID:0060735 |
OMIM:131760 |
J:67320 | |
