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All mouse models of autism spectrum disorder with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | autism spectrum disorder | \Cntnap2tm1Pele/\Cntnap2tm1Pele | B6.129-Cntnap2tm1Pele | J:177110 | View | |||
| autism spectrum disorder | \Cntnap2tm2Pele/\Cntnap2tm2Pele | B6.129(Cg)-Cntnap2tm2Pele | J:229005 | View | ||||
| | autism spectrum disorder | \Arhgap32tm1Taki/\Arhgap32tm1Taki | B6N.Cg-Arhgap32tm1Taki | J:236753 | View | |||
| autism spectrum disorder | \Arhgef10tm1.1Ssfg/\Arhgef10tm1.1Ssfg | B6.129S1-Arhgef10tm1.1Ssfg | J:271943 | View | ||||
| autism spectrum disorder | \Arid1bem1Hzhu/\Arid1b+ | C57BL/6J-Arid1bem1Hzhu | J:256668 | View | ||||
| autism spectrum disorder | \Arid1bem1Iha/\Arid1b+ | C57BL/6J-Arid1bem1Iha | J:271850 | View | ||||
| autism spectrum disorder | \BckdkGt(OST79912)Lex/\BckdkGt(OST79912)Lex | involves: 129S5/SvEvBrd | J:238065 | View | ||||
| autism spectrum disorder | \Brinp1tm1.1Pib/\Brinp1tm1.1Pib | involves: BALB/cJ * C57BL/6 | J:231288 | View | ||||
| autism spectrum disorder | \Cadps2tm1Tfr/\Cadps2tm1Tfr | C57BL/6-Cadps2tm1Tfr | J:121256 | View | ||||
| autism spectrum disorder | \Camk2aem1Rjco/\Camk2aem1Rjco | involves: C57BL/6J * DBA/2J | J:239596 | View | ||||
| autism spectrum disorder | \Chd8tm1.1Csbd/\Chd8+ | involves: C57BL/6J | J:267025 | View | ||||
| autism spectrum disorder | \Chd8tm1Kei/\Chd8+ | involves: 129P2/OlaHsd * C57BL/6J | J:235128 | View | ||||
| autism spectrum disorder | \Chd8tm2.1Kei/\Chd8+ | B6J.129P2-Chd8tm2.1Kei | J:235128 | View | ||||
| autism spectrum disorder | \Chrnb2tm1Jpc/\Chrnb2tm1Jpc | involves: 129P2/OlaHsd | J:99880 | View | ||||
| autism spectrum disorder | \Crebbptm2Pkb/\Crebbptm2Pkb | (B6.129P2-Crebbptm2Pkb/Pkb x 129S2.129P2(B6)-Crebbptm2Pkb/Pkb)F1 | J:230850 | View | ||||
| autism spectrum disorder |
\Ctnnb1tm2Kem/\Ctnnb1tm2Kem \Pvalbtm1(cre)Arbr/\Pvalb+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 | J:236989 | View | ||||
| autism spectrum disorder | \Dlg4tm2.1Grnt/\Dlg4tm2.1Grnt | involves: 129P2/OlaHsd * C57BL/6J | J:175436 | View | ||||
| autism spectrum disorder | \Dlgap4Gt(XH723)Byg/\Dlgap4Gt(XH723)Byg | B6.129P2-Dlgap4Gt(XH723)Byg | J:277713 | View | ||||
| autism spectrum disorder | \Dp(7Herc2-Mkrn3)1Taku/0 | B6J.129S7-Dp(7Herc2-Mkrn3)1Taku | J:225285 | View | ||||
| autism spectrum disorder | \Dp(7Herc2-Mkrn3)1Taku/0 | involves: 129S7/SvEvBrd * C57BL/6 | J:151648 | View | ||||
| autism spectrum disorder | \Dp(7Herc2-Mkrn3)1Taku/0 | involves: 129S7/SvEvBrd * C57BL/6J | J:190050 | View | ||||
| autism spectrum disorder | \Eif4ebp2tm1Klan/\Eif4ebp2tm1Klan | B6.129S4(C)-Eif4ebp2tm1Klan | J:194221 | View | ||||
| autism spectrum disorder | \Elp2em2Bjw/\Elp2em2Bjw | involves: C57BL/6 | J:306113 | View | ||||
| autism spectrum disorder | \Elp2em2Bjw/\Elp2em2Bjw | involves: C57BL/6 * DBA/2J | J:306113 | View | ||||
| autism spectrum disorder | \Elp2em2Bjw/\Elp2em3Bjw | involves: C57BL/6 * DBA/2J | J:306113 | View | ||||
| autism spectrum disorder | \En2tm1Alj/\En2tm1Alj | involves: 129S2/SvPas * C57BL/6 | J:114464 | View | ||||
| autism spectrum disorder |
\Ext1tm1Yama/\Ext1tm1Yama \Tg(Camk2a-cre)2834Lusc/0 |
involves: 129S5/SvEvBrd * C57BL/6 | J:182220 | View | ||||
| autism spectrum disorder | \Fmr1tm1Cgr/Y | B6.129P2-Fmr1tm1Cgr/Nwu | J:171069 | View | ||||
| autism spectrum disorder |
\Fmr1tm1Cgr/Y \Tg(ACTB-Eif4e)#Ppp/0 |
involves: 129P2/OlaHsd * C57BL/6 | J:227667 | View | ||||
| autism spectrum disorder | \Frmd5em#Yuw/\Frmd5em#Yuw | C57BL/6J-Frmd5em#Yuw | J:345640 | View | ||||
| autism spectrum disorder | \Gabrb3tm1Geh/\Gabrb3tm1Geh | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:130259 | View | ||||
| autism spectrum disorder | \Gabrb3tm2.1Uru/\Gabrb3tm2.1Uru | B6J.129S6(Cg)-Gabrb3tm2.1Uru | J:228332 | View | ||||
| autism spectrum disorder | \Gprasp2tm1.1Jpe/Y | B6.129(FVB)-Gprasp2tm1.1Jpe | J:273373 | View | ||||
| autism spectrum disorder | \Grin1tm1Bhk/\Grin1tm1Bhk | involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2 | J:203256 | View | ||||
| autism spectrum disorder | \Gstm1tm1Gcw/\Gstm1tm1Gcw | involves: 129S/SvEv * C57BL/6 | J:159701 | View | ||||
| autism spectrum disorder | \Itpr3tf/\Itpr3tf | BTBR T+ Itpr3tf/J | J:138605, J:138842, J:222265 | View | ||||
| autism spectrum disorder | \Jakmip1tm1(KOMP)Vlcg/\Jakmip1tm1(KOMP)Vlcg | involves: C57BL/6NTac | J:228732 | View | ||||
| autism spectrum disorder | \Lrfn2tm1.1Jaru/\Lrfn2tm1.1Jaru | B6J.129P2-Lrfn2tm1.1Jaru | J:241916 | View | ||||
| autism spectrum disorder |
\Mapk1tm1.2Kuta/\Mapk1tm1.2Kuta \Tg(Nes-cre)1Kag/0 |
involves: 129P2/OlaHsd * C57BL/6J | J:176051 | View | ||||
| autism spectrum disorder |
\Mettm1Sst/\Mettm1Sst \Tg(mI56i-cre,-EGFP)1Kc/0 |
involves: 129P2/OlaHsd * C57BL/6J * FVB | J:170554 | View | ||||
| autism spectrum disorder | \NbeaTg(GH1)240BNec/\Nbea+ | B6JRj.Cg-NbeaTg(GH1)240BNec | J:197577 | View | ||||
| autism spectrum disorder | \Nexmiftm1(KOMP)Wtsi/Y | B6J.B6N-Nexmiftm1(KOMP)Wtsi | J:283395 | View | ||||
| autism spectrum disorder | \Nlgn1em1Taku/\Nlgn1+ | involves: C57BL/6J | J:247060 | View | ||||
| autism spectrum disorder | \Nlgn1em1Taku/\Nlgn1em1Taku | involves: C57BL/6J | J:247060 | View | ||||
| autism spectrum disorder | \Nlgn3tm1Bros/\Nlgn3tm1Bros | B6.Cg-Nlgn3tm1Bros | J:151116 | View | ||||
| autism spectrum disorder | \Nlgn3tm1Rhn/Y | involves: 129S6/SvEvTac * C57BL/6 | J:187744 | View | ||||
| autism spectrum disorder | \Nlgn3tm1Sud/Y | involves: 129S1/Sv * 129X1/SvJ | J:214636 | View | ||||
| autism spectrum disorder | \Nlgn3tm1Sud/Y | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:125344 | View | ||||
| autism spectrum disorder | \Nlgn3tm2.1Sud/Y | involves: 129S1/Sv * 129X1/SvJ | J:214636 | View | ||||
| autism spectrum disorder | \Nlgn4lGt(XST093)Byg/\Nlgn4lGt(XST093)Byg | B6.129P2-Nlgn4xGt(XST093)Byg | J:131843 | View | ||||
| autism spectrum disorder | \Nrcamtm1Gmt/\Nrcamtm1Gmt | involves: 129S6/SvEvTac * Swiss Webster | J:153165 | View | ||||
| autism spectrum disorder | \Nrp2tm1.2Mom/\Nrp2tm1.2Mom | involves: 129P2/OlaHsd * C57BL/6 * FVB/NJ | J:166116 | View | ||||
| autism spectrum disorder | \Nrxn1tm1Sud/\Nrxn1tm1Sud | involves: 129 * C57BL/6 | J:153748 | View | ||||
| autism spectrum disorder | \Nrxn2tm1Sud/\Nrxn2tm1Sud | involves: 129 * C57BL/6 * C57BL/6J * C57BL/6NClr | J:220076 | View | ||||
| autism spectrum disorder | \Nsftm1Himat/\Nsf+ | C57BL/6N-Nsftm1Himat | J:313900 | View | ||||
| autism spectrum disorder | \Oprm1tm1Kff/\Oprm1tm1Kff | involves: 129S2/SvPas * C57BL/6J | J:204731 | View | ||||
| autism spectrum disorder | \Pak2Gt(OST104058)Lex/\Pak2+ | B6;129S5-Pak2Gt(OST104058)Lex/J | J:271067 | View | ||||
| autism spectrum disorder |
\Pdgfrbtm1Msas/\Pdgfrbtm1Msas \Tg(Nes-cre)1Nogu/0 |
B6J.Cg-Pdgfrbtm1Msas Tg(Nes-cre)1Nogu | J:229179 | View | ||||
| autism spectrum disorder | \Pianptm1d(KOMP)Wtsi/\Pianptm1d(KOMP)Wtsi | involves: BALB/cJ * C57BL/6N * SJL | J:279537 | View | ||||
| autism spectrum disorder | \Pogzem1Tnkw/\Pogz+ | involves: C57BL/6NJcl | J:286398 | View | ||||
| autism spectrum disorder | \Prex1tm1Hcew/\Prex1tm1Hcew | involves: 129P2/OlaHsd * C57BL/6 | J:228203 | View | ||||
| autism spectrum disorder | \Prickle1em1Yzou/\Prickle1+ | C57BL/6-Prickle1em1Yzou | J:321396 | View | ||||
| autism spectrum disorder | \Prickle1em1Yzou/\Prickle1em1Yzou | C57BL/6-Prickle1em1Yzou | J:321396 | View | ||||
| autism spectrum disorder | \Ptentm1Rps/\Pten+ | B6.129S1-Ptentm1Rps/Nci | J:235927 | View | ||||
| autism spectrum disorder |
\Ptentm1Rps/\Pten+ \Slc6a4tm1Kpl/\Slc6a4+ |
B6.129-Slc6a4tm1Kpl Ptentm1Rps | J:144937 | View | ||||
| autism spectrum disorder | \Ptentm2.1Ppp/\Ptentm2.1Ppp | involves: 129S1/Sv | J:181347 | View | ||||
| autism spectrum disorder | \Scn1atm1Wac/\Scn1a+ | B6.129-Scn1atm1Wac | J:188126 | View | ||||
| autism spectrum disorder |
\Scn1atm2.1Wac/\Scn1a+ \Tg(I12b-cre)1Jlr/0 |
involves: 129X1/SvJ * C57BL/6J | J:188126 | View | ||||
| autism spectrum disorder | \Scn2aem1Gsp/\Scn2a+ | involves: C57BL/6J * SJL/J | J:311772 | View | ||||
| autism spectrum disorder | \Sh3rf2tm1Zhxu/\Sh3rf2+ | C57BL/6-Sh3rf2tm1Zhxu | J:270945 | View | ||||
| autism spectrum disorder |
\Sh3rf2tm1Zhxu/\Sh3rf2+ \Tg(Thy1-EGFP)MJrs/0 |
involves: C57BL/6 * C57BL/6J * CBA | J:270945 | View | ||||
| autism spectrum disorder | \Shank2tm1.1Tmb/\Shank2tm1.1Tmb | B6.129-Shank2tm1.1Tmb | J:186719 | View | ||||
| autism spectrum disorder | \Shank2tm1Mgle/\Shank2tm1Mgle | B6.129S4-Shank2tm1Mgle | J:186718, J:237188 | View | ||||
| autism spectrum disorder | \Shank3em1Hzo/\Shank3em1Hzo | involves: C57BL/6J | J:305052 | View | ||||
| autism spectrum disorder | \Shank3tm1.1Pfw/\Shank3+ | B6.129S6-Shank3tm1.1Pfw | J:198768 | View | ||||
| autism spectrum disorder | \Shank3tm1.2Bux/\Shank3+ | C57BL/6-Shank3tm1.2Bux | J:175320 | View | ||||
| autism spectrum disorder | \Shank3tm1Cmpl/\Shank3tm1Cmpl | B6J.129S6-Shank3tm1Cmpl | J:224381 | View | ||||
| autism spectrum disorder | \Shank3tm1Yhj/\Shank3tm1Yhj | B6.129S7-Shank3tm1Yhj | J:173402 | View | ||||
| autism spectrum disorder | \Shank3tm2Cmpl/\Shank3+ | B6.129S6-Shank3tm2Cmpl | J:289874 | View | ||||
| autism spectrum disorder | \Shank3tm2Cmpl/\Shank3tm2Cmpl | B6.129S6-Shank3tm2Cmpl | J:289874 | View | ||||
| autism spectrum disorder | \Shank3tm2Gfng/\Shank3+ | B6.129-Shank3tm2Gfng/J | J:243083 | View | ||||
| autism spectrum disorder | \Shank3tm2Gfng/\Shank3tm2Gfng | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:171113 | View | ||||
| autism spectrum disorder | \Shank3tm3.1Gfng/\Shank3tm3.1Gfng | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:230887 | View | ||||
| autism spectrum disorder | \Shank3tm3.2Cmpl/\Shank3+ | B6.129S6(Cg)-Shank3tm3.2Cmpl | J:289884 | View | ||||
| autism spectrum disorder | \Shank3tm3.2Cmpl/\Shank3tm3.2Cmpl | B6.129S6(Cg)-Shank3tm3.2Cmpl | J:289884 | View | ||||
| autism spectrum disorder | \Shank3tm5.1Gfng/\Shank3tm5.1Gfng | involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J | J:229668 | View | ||||
| autism spectrum disorder | \Slc6a4tm1Kpl/\Slc6a4tm1Kpl | B6.129-Slc6a4tm1Kpl | J:192363 | View | ||||
| autism spectrum disorder | \Slc6a4tm2.1Rbl/\Slc6a4tm2.1Rbl | involves: 129S4/SvJae * 129S6/SvEvTac | J:202876, J:237081 | View | ||||
| autism spectrum disorder |
\Slc7a5tm1.1Daca/\Slc7a5tm1.1Daca \Tg(Tek-cre)12Flv/0 |
B6J.Cg-Slc7a5tm1.1Daca Tg(Tek-cre)12Flv | J:238065 | View | ||||
| autism spectrum disorder | \Slc9a9tm1.1Yzj/\Slc9a9tm1.1Yzj | Not Specified | J:265802 | View | ||||
| autism spectrum disorder |
\Slc9a9tm2c(KOMP)Wtsi/\Slc9a9tm2c(KOMP)Wtsi \Tg(Nes-cre)1Kln/0 |
involves: C57BL/6 * C57BL/6N * SJL | J:258593 | View | ||||
| autism spectrum disorder | \Slc9a9tm2d(KOMP)Wtsi/\Slc9a9tm2d(KOMP)Wtsi | involves: C57BL/6 * C57BL/6N * SJL | J:258593 | View | ||||
| autism spectrum disorder | \Syn1tm1Pggd/\Syn1tm1Pggd | B6.129P2-Syn1tm1Pggd | J:201707 | View | ||||
| autism spectrum disorder | \Syn2tm1Pggd/\Syn2tm1Pggd | B6.1129-Syn2tm1Pggd | J:201707 | View | ||||
| autism spectrum disorder | \Syn3tm1Pggd/\Syn3tm1Pggd | B6.129X1-Syn3tm1Jfe | J:201707 | View | ||||
| autism spectrum disorder | \Tafa3em1Hssh/\Tafa3em1Hssh | C57BL/6NTac-Tafa3em1Hssh | J:257371 | View | ||||
| autism spectrum disorder | \Tbr1tm1.1Csbd/\Tbr1+ | involves: C57BL/6J | J:281878 | View | ||||
| autism spectrum disorder | \Tbr1tm1Jlr/\Tbr1+ | B6.129X1-Tbr1tm1Jlr | J:208050 | View | ||||
| autism spectrum disorder | \Tbx1tm1Bem/\Tbx1+ | B6.Cg-Tbx1tm1Bem | J:177772 | View | ||||
| autism spectrum disorder | \Tcf20em1Jwji/\Tcf20+ | Not Specified | J:306854 | View | ||||
| autism spectrum disorder | \Tg(ACTB-Eif4e)#Ppp/? | B6.Cg-Tg(ACTB-Eif4e)#Ppp | J:194400 | View | ||||
| autism spectrum disorder | \Tmprss9tm1.3Hzo/\Tmprss9tm1.3Hzo | involves: 129S1/Sv * C57BL/6J * C57BL/6NTac | J:284914 | View | ||||
| autism spectrum disorder |
\Tsc1tm1Djk/\Tsc1tm1Djk \Tg(Pcp2-cre)2Mpin/0 |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/cJ * C57BL/6J | J:186699 | View | ||||
| autism spectrum disorder | \Tsc1tm1Hin/\Tsc1+ | B6J.129S4-Tsc1tm1Hin | J:221239 | View | ||||
| autism spectrum disorder | \Tsc2tm1Djk/\Tsc2+ | involves: 129S4/SvJae * C57BL/6J | J:217829 | View | ||||
| autism spectrum disorder | \Tsc2tm1Tno/\Tsc2+ | B6J.129S4-Tsc2tm1Tno | J:221239 | View | ||||
| autism spectrum disorder |
\Tshz3tm2.1Lafa/\Tshz3tm2.1Lafa \Tg(Camk2a-cre)2Gsc/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:294534 | View | ||||
| autism spectrum disorder | \Vrk3Gt(YTA189)Byg/\Vrk3Gt(YTA189)Byg | B6.129P2-Vrk3Gt(YTA189)Byg | J:249352 | View | ||||
| autism spectrum disorder | \Wdfy3disc/\Wdfy3disc | involves: C57BL/6J * FVB/NJ | J:225200 | View | ||||
| autism spectrum disorder | \Wdfy3tm1a(KOMP)Mbp/\Wdfy3tm1a(KOMP)Mbp | C57BL/6N-Wdfy3tm1a(KOMP)Mbp | J:225200 | View | ||||
| autistic disorder | \Ank2em1Bnt/\Ank2em1Bnt | C57BL/6J-Ank2em1Bnt | J:277752 | View | ||||
| autistic disorder | \Ank2tm1Bnt/\Ank2tm1Bnt | B6.129-Ank2tm1Bnt/Bnt | J:277752 | View | ||||
| Transgenes and Other Mutations | autism spectrum disorder | \Del(7Chrna7-Fan1)1Mima/\+ | C57BL/6N-Del(7Chrna7-Fan1)1Mima | J:227984 | View | |||
| autism spectrum disorder | \Del(7Coro1a-Spn)1Dolm/\+ | involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6N * CD-1 | J:210018 | View | ||||
| autism spectrum disorder | \Del(7Slx1b-Sept1)4Aam/0 | B6129S-Del(7Slx1b-Sept1)4Aam/J | J:219859 | View | ||||
| autism spectrum disorder | \Del(7Slx1b-Sept1)4Aam/\+ | involves: 129S7/SvEvBrd * C57BL/6N | J:176335 | View | ||||
| autism spectrum disorder | \Tg(Mov1/Tyr)OVE876BPay/\Tg(Mov1/Tyr)OVE876BPay | FVB/N-Tg(Mov1/Tyr)OVE876BPay | J:167614 | View | ||||
| autism spectrum disorder | \Tg(Mov1/Tyr)OVE876BPay/Y | FVB/N-Tg(Mov1/Tyr)OVE876BPay | J:167614 | View | ||||
| Additional Complex Models | autism spectrum disorder |
\Efna2tm1Jgf/\Efna2tm1Jgf \Efna3tm1Rax/\Efna3tm1Rax |
involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster | J:216970 | View | |||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | autism spectrum disorder | \Tg(Camk2a-Bdnf)A9Stl/0 | C57BL/6-Tg(Camk2a-Bdnf)A9Stl/J | J:216846 | View | |||