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Gprasp2tm1.1Jpe
Targeted Allele Detail
Summary
Symbol: Gprasp2tm1.1Jpe
Name: G protein-coupled receptor associated sorting protein 2; targeted mutation 1.1, Joao Peca
MGI ID: MGI:6287842
Gene: Gprasp2  Location: ChrX:134739786-134745480 bp, + strand  Genetic Position: ChrX, 57.3 cM
Alliance: Gprasp2tm1.1Jpe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:273373
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 7 was flanked by loxP sites and an frt-flanked neomycin cassette was inserted downstream of the floxed exon. Germline cre-mediated recombination deleted exon 7. (J:273373)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gprasp2 Mutation:  7 strains or lines available
References
Original:  J:273373 Edfawy M, et al., Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice. Nat Commun. 2019 Mar 29;10(1):1431
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory