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Gene Expression Data
Assay Details
Assay
Reference: J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
Assay type: RNA in situ
MGI Accession ID: MGI:8350553
Gene symbol: Prl3d1
Gene name: prolactin family 3, subfamily d, member 1
Probe: Pl-1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A - Chp1 +/- E9.5; Ext8F: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present 5A Chp1+/- E9.5 Pl-1 , Extended Data 8F +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen 5A - Chp1 -/- E9.5; Ext8F: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present 5A Chp1-/- E9.5 Pl-1 , Extended Data 8F -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is reduced compared to controls.
Specimen 5B - Alg3 +/- E10.5; Ext16H +/-: embryonic day 10.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Level Pattern Image Note
TS17: trophoblast giant cell Present Extended Data 16H +/- Pl-1 , 5B Alg3+/- E10.5 Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen 5B - Alg3 -/- E10.5; Ext16H -/-: embryonic day 10.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: trophoblast giant cell Present Extended Data 16H -/- Pl-1 , 5B Alg3-/- E10.5 Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is reduced compared to controls.
Specimen Zmym2 +/- E9.5: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 5E +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Zmym2 -/- E9.5: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 5E -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is comparable to that seen in controls.
Specimen Ppox +/- E9.5: embryonic day 9.5; Ppoxem1(IMPC)J/Ppox+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 9D +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Ppox -/- E9.5: embryonic day 9.5; Ppoxem1(IMPC)J/Ppoxem1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 9D -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is expanded compared to controls.
Specimen Urm1 +/- E9.5: embryonic day 9.5; Urm1em1(IMPC)J/Urm1+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 10E +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Urm1 -/- E9.5: embryonic day 9.5; Urm1em1(IMPC)J/Urm1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 10E -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs). In mutants development of this layer is variable. In 2 of the placentas examined, the layer was reduced compared to controls, but it was normal in 2 other instances.
Specimen Gmeb2 +/- E9.5: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 11E +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Gmeb2 -/- E9.5: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 11E -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is comparable to that seen in controls.
Specimen Kctd5 +/- E9.5: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 12E +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Kctd5 -/- E9.5: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 12E -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is comparable to that seen in controls.
Specimen Rprd2 +/- E9.5: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 13E +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Rprd2 -/- E9.5: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 13E -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is comparable to that seen in controls.
Specimen Got2 +/- E9.5: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2+ (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 14E +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Got2 -/- E9.5: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2em1(IMPC)Mbp (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Extended Data 14E -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is reduced compared to controls.
Specimen Arpc1a +/- E10.5: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Level Pattern Image Note
TS17: trophoblast giant cell Present Extended Data 15H +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Arpc1a -/- E10.5: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: trophoblast giant cell Present Extended Data 15H -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is comparable to that seen in controls.
Specimen Bltp2 +/- E10.5: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Level Pattern Image Note
TS17: trophoblast giant cell Present Extended Data 17H +/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs).
Specimen Bltp2 -/- E10.5: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: trophoblast giant cell Present Extended Data 17H -/- Pl-1 Expression is seen in parietal trophoblast giant cells (P-TGCs); in mutants this layer is reduced compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
MGI 6.29 		The Jackson Laboratory