Excel File Text File All mouse models of amyotrophic lateral sclerosis with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      amyotrophic lateral sclerosis type 1 Cybbtm1Din/Y
Tg(SOD1*G93A)dl1Gur/0
B6.Cg-Cybbtm1Din Tg(SOD1*G93A)dl1Gur J:111782 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur/0 B6.Cg-Tg(SOD1*G93A)1Gur J:155140 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur/0 B6.Cg-Tg(SOD1*G93A)1Gur/J J:211734 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G127X)716Mrkl/Tg(SOD1*G127X)716Mrkl B6JBom.Cg-Tg(SOD1*G127X)716Mrkl J:175594 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur/0 B6SJL-Tg(SOD1*G93A)1Gur J:144199 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur/0 B6SJL-Tg(SOD1*G93A)1Gur/J J:133155, J:143173, J:146652, J:212250 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*)DF7Yaw/0 C57BL/6-Tg(SOD1*)DF7Yaw J:97932 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*)DF7Yaw/Tg(SOD1*)DF7Yaw C57BL/6-Tg(SOD1*)DF7Yaw J:97932 View
amyotrophic lateral sclerosis type 1 Tg(Myl1-SOD1*G93A)#Amu/0 FVB/NJ-Tg(Myl1-SOD1*G93A)#Amu J:143747 View
amyotrophic lateral sclerosis type 1 Isl1tm1(cre)Tmj/Isl1+
Tg(SOD1*G37R)1Dwc/0
involves: 129X1/SvJ * C57BL/6 J:109131 View
amyotrophic lateral sclerosis type 1 Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo/Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo involves: C3H * C57BL/6 J:104655 View
amyotrophic lateral sclerosis type 1 Sod1m1H/Sod1m1H involves: C3H/HeH * C57BL/6J J:219360 View
amyotrophic lateral sclerosis type 1 Tg(SOD1)2Gur/0
Tg(SOD1*)D-14Dbo/0
involves: C3H/HeJ * C57BL/6 * C57BL/6J * SJL J:218091 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)106Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)42Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)9Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)29Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178, J:119631 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R*H48Q)58Dbo/0 involves: C3H/HeJ * C57BL/6J J:119631 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*)125Dbo/? involves: C3H/HeJ * C57BL/6J J:86421 View
amyotrophic lateral sclerosis type 1 Tg(SOD1)2Gur/0
Tg(SOD1*G85R)#Roos/0
involves: C57BL/6 * C57BL/6J * SJL J:147156 View
amyotrophic lateral sclerosis type 1 Tg(ITGAM-cre)2781Gkl/0
Tg(SOD1*G37R)1Dwc/0
involves: C57BL/6 * CBA J:109131 View
amyotrophic lateral sclerosis type 1 Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd involves: C57BL/6 * CBA * FVB J:134095 View
amyotrophic lateral sclerosis type 1 Tg(Thy1-SOD1*G93A)T1Hgrd/0
Tg(Thy1-SOD1*G93A)T3Hgrd/0
involves: C57BL/6 * CBA * FVB J:134095 View
amyotrophic lateral sclerosis type 1 Tg(Prnp-Immt/SOD1*G93A)7Gmnf/Tg(Prnp-Immt/SOD1*G93A)7Gmnf involves: C57BL/6 * CBA * SJL J:177846 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)#Maw/0 involves: C57BL/6 * DBA/2 J:99701 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)IAra/0 involves: C57BL/6 * DBA/2 J:221350 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)2Gur/0 involves: C57BL/6 * SJL J:32665, J:78629, J:89928 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur/0 involves: C57BL/6 * SJL J:76718, J:91800, J:109458, J:130581 View
amyotrophic lateral sclerosis type 1 Tg(SOD1)2Gur/0
Tg(SOD1*G93A)1Gur/0
involves: C57BL/6 * SJL J:109458 View
amyotrophic lateral sclerosis type 1 Tg(SOD1)2Gur/0
Tg(SOD1*A4V)A1073Gur/0
involves: C57BL/6 * SJL J:109458 View
amyotrophic lateral sclerosis type 1 Tg(SOD1)2Gur/0
Tg(SOD1*L126Z)#Deng/0
involves: C57BL/6 * SJL J:109458 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)dl1Gur/0 involves: C57BL/6 * SJL J:106420 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*L126Z)#Deng/0 involves: C57BL/6 * SJL J:109458 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)#Roos/0 involves: C57BL/6J J:147156 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R/EYFP)641Alho/Tg(SOD1*G85R/EYFP)641Alho involves: C57BL/6J * SJL/J J:144475 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R/EYFP)737Alho/Tg(SOD1*G85R/EYFP)737Alho involves: C57BL/6J * SJL/J J:212250 View
amyotrophic lateral sclerosis type 1 Tg(Sod1*G86R)M1Jwg/0 involves: FVB/N J:22628, J:58733, J:91800 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)148Dwc/? Not Specified J:77600 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)74Dwc/? Not Specified J:77600 View
amyotrophic lateral sclerosis type 6 Meox2tm1(cre)Sor/Meox2+
Tg(CAG-lacZ,-FUS,-EGFP)629Gyu/0
involves: 129S4/SvJaeSor * C57BL/6 J:216672 View
amyotrophic lateral sclerosis type 6 Meox2tm1(cre)Sor/Meox2+
Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu/0
involves: 129S4/SvJaeSor * C57BL/6 J:216672 View
amyotrophic lateral sclerosis type 6 Fustm1.1Emcf/Fus+ involves: C3H * C57BL/6J * C57BL/6N J:249965 View
amyotrophic lateral sclerosis type 6 Tg(Prnp-FUS)WT3Cshw/Tg(Prnp-FUS)WT3Cshw involves: C57BL/6 * Crl:CD-1(ICR) J:189360 View
amyotrophic lateral sclerosis type 6 Tg(Prnp-FUS*R521C)3313Ejh/0 involves: C57BL/6 * SJL J:209419 View
amyotrophic lateral sclerosis type 10 Tardbptm1.1Neas/Tardbptm1.1Neas B6(C3)-Tardbptm1.1Neas J:283769 View
amyotrophic lateral sclerosis type 10 Tardbptm2.1Neas/Tardbptm2.1Neas B6(C3)-Tardbptm2.1Neas J:283769 View
amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*Q331K)103Dwc/0 B6N.Cg-Tg(Prnp-TARDBP*Q331K)103Dwc/J J:242322 View
amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)3cPtrc/Tg(Prnp-TARDBP)3cPtrc C57BL/6-Tg(Prnp-TARDBP)3cPtrc J:163231 View
amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP*)BOddo/Tg(Thy1-TARDBP*)BOddo C57BL/6-Tg(Thy1-TARDBP*)BOddo J:223932 View
amyotrophic lateral sclerosis type 10 Tardbpem1Rhbr/Tardbpem1Rhbr C57BL/6J-Tardbpem1Rhbr J:261673 View
amyotrophic lateral sclerosis type 10 Mnx1tm4(cre)Tmj/Mnx1+
Tardbptm1.1Ckjs/Tardbptm1.2Cjks
involves: 129S1/Sv * C57BL/6J J:190254 View
amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)96Dwc/0
Tg(Prnp-TARDBP*Q331K)31Dwc/0
involves: C3H * C57BL/6 J:239141 View
amyotrophic lateral sclerosis type 10 Tg(TARDBP)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
amyotrophic lateral sclerosis type 10 Tg(TARDBP*A315T)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
amyotrophic lateral sclerosis type 10 Tg(TARDBP*G348C)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
amyotrophic lateral sclerosis type 10 Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-TARDBP)12Vle/0
involves: C3H/HeJ * C57BL/6J J:170756 View
amyotrophic lateral sclerosis type 10 Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-TARDBP*)4Vle/0
involves: C3H/HeJ * C57BL/6J J:170756 View
amyotrophic lateral sclerosis type 10 Tg(NEFH-tTA)8Vle/0
Tg(tetO-TARDBP*)4Vle/0
involves: C3H/HeJ * C57BL/6J J:225639 View
amyotrophic lateral sclerosis type 10 Tg(tetO-TARDBP*A315T)13Lmit/0
Tg(Thy1-tTA)6Lmit/0
involves: C57BL/6 J:245760, J:242322 View
amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh involves: C57BL/6 * C57BL/6J * SJL J:157550 View
amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*A315T)95Balo/0 involves: C57BL/6 * CBA J:153197 View
amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*A315T)23Jlel/0 involves: C57BL/6 * CD-1 * SJL J:165985 View
amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)4Jlel/0 involves: C57BL/6 * CD-1 * SJL J:165985 View
amyotrophic lateral sclerosis type 10 Tardbptm3.1Ckjs/Tardbp+ involves: C57BL/6J J:285792 View
amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)4Singh/0 involves: C57BL/6J * SJL/J J:157550 View
amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh involves: C57BL/6J * SJL/J J:157550 View
      amyotrophic lateral sclerosis Epg5tm1Ygz/Epg5tm1Ygz involves: 129S1/Sv * 129X1/SvJ * C57BL/6N J:196603 View
amyotrophic lateral sclerosis Adarb1tm1.1Skwa/Adarb1tm1.1Skwa
Tg(SLC18A3-cre)KMisa/0
involves: C57BL/6 J:164294 View
amyotrophic lateral sclerosis Psmc4tm1.1Ryot/Psmc4tm1.2Ryot
Tg(SLC18A3-cre)KMisa/0
involves: C57BL/6 * C57BL/6N J:193770 View
amyotrophic lateral sclerosis Zfp106tm1b(KOMP)Wtsi/Zfp106tm1b(KOMP)Wtsi involves: C57BL/6N J:241305 View
amyotrophic lateral sclerosis type 1 Tg(Thy1-Sncg)HvP36Putt/? C57BL/6-Tg(Thy1-Sncg)HvP36Putt J:185793 View
amyotrophic lateral sclerosis type 1 Vegfatm2Pec/Vegfatm2Pec involves: 129S1/Sv * 129X1/SvJ J:69797 View
amyotrophic lateral sclerosis type 1 Sod2tm1Cje/Sod2tm1Cje involves: C57BL/6J J:45913 View
amyotrophic lateral sclerosis type 1 Vps54wr/Vps54wr involves: C57BL/6J * C57BL/Fa J:181019, J:196432 View
      amyotrophic lateral sclerosis type 1 Tg(Thy1-DCTN1*G59S)M2Pcw/? involves: C57BL/6 * SJL J:132857 View
amyotrophic lateral sclerosis type 1 Tg(NFH)120Jpj/0 Not Specified J:69180 View
amyotrophic lateral sclerosis type 1 Tg(NFH)120Jpj/Tg(NFH)120Jpj Not Specified J:69180 View
amyotrophic lateral sclerosis type 1 Tg(NEFH)200Jpj/0 Not Specified J:69180 View
amyotrophic lateral sclerosis type 1 Tg(NEFH)200Jpj/Tg(NEFH)200Jpj Not Specified J:69180 View
amyotrophic lateral sclerosis type 8 Tg(Thy1-VAPB*P56S,-EGFP)D3Cai/0 C57BL/6-Tg(Thy1-VAPB*P56S,-EGFP)D3Cai J:202148 View
amyotrophic lateral sclerosis type 15 Tg(Thy1-UBQLN2*P497S)3Mont/? involves: C3H * C57BL/6 * C57BL/6J J:239510 View
amyotrophic lateral sclerosis type 15 Tg(Thy1-UBQLN2*P506T)6Mont/? involves: C3H * C57BL/6 * C57BL/6J J:239510 View
amyotrophic lateral sclerosis type 17 Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1Tg(Thy1-CHMP2B*)1Rene involves: C57BL/6 * DBA/2 * FVB/N J:237873 View
amyotrophic lateral sclerosis type 17 Atp2b1Tg(Thy1-CHMP2B*)1Rene/Atp2b1+ involves: C57BL/6 * DBA/2 * FVB/N J:237873 View
amyotrophic lateral sclerosis type 18 Mdga2Tg(Prnp-PFN1*G118V)838Kiaei/Mdga2+ involves: C57BL/6N J:241428 View
amyotrophic lateral sclerosis type 18 Tg(Prnp-PFN1*C71G)22Zxu/0
Tg(Thy1-PFN1*C71G)67Zxu/Tg(Thy1-PFN1*C71G)67Zxu
involves: FVB/N J:235427 View
frontotemporal dementia and/or amyotrophic lateral sclerosis-1 Tg(C9orf72)500Lpwr/0 FVB/NJ-Tg(C9orf72)500Lpwr J:239579 View
Transgenes and
Other Mutations
     amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R*H48Q)139Dbo/0 involves: C3H/HeJ * C57BL/6J J:119631 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*L126Z)45Dbo/0 involves: C3H/HeJ * C57BL/6J J:219482 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*)D-14Dbo/0 involves: C3H/HeJ * C57BL/6J J:218091 View
amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)LAra/0 involves: C57BL/6 * DBA/2 J:221350 View
amyotrophic lateral sclerosis type 6 Tg(Thy1-FUS*)19Vlb/0 B6.Cg-Tg(Thy1-FUS*)19Vlb J:203550 View
amyotrophic lateral sclerosis type 10 Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu/0 involves: C57BL/6 * C57BL/6J * FVB/NJ * SJL J:207750 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      amyotrophic lateral sclerosis type 2 Als2tm1Garo/Als2tm1Garo either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) J:138147 View
amyotrophic lateral sclerosis type 2 Als2tm1Jei/Als2tm1Jei involves: 129P2/OlaHsd * C57BL/6J J:104446 View
amyotrophic lateral sclerosis type 2 Als2tm1Cai/Als2tm1Cai involves: 129X1/SvJ * C57BL/6J J:100336 View