Analysis Tools
mortality/aging
|
• expression of Cre in microglia extends the lifespan of mutant SOD1-expressing mice by an average of 99 days compared to non-ITGAM-cre expressing mice
|
nervous system
|
• progression of later stage disease is slowed by an average of 75 days in mice expressing both transgenes
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| amyotrophic lateral sclerosis type 1 | DOID:0060193 |
OMIM:105400 |
J:109131 | |
