About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3813319
Allelic
Composition
Tg(SOD1*G93A)dl1Gur/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SOD1*G93A)dl1Gur mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mean 266 day

nervous system
• mice develop neurofilament-rich Lewy-body like inclusions in the perikarya and proximal axons of the spinal cord motorneurons at day 180 that increase with age but are not as prominent as in Tg(SOD1*G93A)1Gur mice
• at day 200, both fast and slow axonal transport are impaired in the ventral root compared to in wild-type axons

behavior/neurological
• develops at day 200
• at day 250 (J:106420)

muscle
• develops at day 200

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
amyotrophic lateral sclerosis type 1 DOID:0060193 OMIM:105400
J:106420


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory