Phenotypes Associated with This Genotype

Genotype
MGI:3832567

• Allelic Composition: Tg(SOD1*G85R)74Dwc/?
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:77600 )

• weakened grip strength in one hindlimb first observed by 12-14 months and spreading rapidly to other limbs

paralysis ( J:77600 )

• complete paralysis occurs two weeks after onset of weakened grip strength

hindlimb paralysis ( J:77600 )

• hindlimb paralysis is first observed at 12-14 months

muscle

muscular atrophy ( J:77600 )

progressive muscle weakness ( J:77600 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
amyotrophic lateral sclerosis type 1		DOID:0060193	OMIM:105400	J:77600