Zfp106^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Zfp106^{tm1b(KOMP)Wtsi}
• Name: zinc finger protein 106; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:6149962
• Synonyms: Zfp106^-, Zfp106^lacz, Zfp106^laczDELTA, Zfp106-null
• Gene: Zfp106 Location: Chr2:120337301-120394324 bp, - strand Genetic Position: Chr2, 60.37 cM, cytoband F1
• Alliance: Zfp106^{tm1b(KOMP)Wtsi} page
• IMPC: Zfp106 gene page

Mutation origin

• Mutant Cell Line: EPD0033_4_C03
• Germline Transmission: Earliest citation of germline transmission: J:241305
• Parent Cell Line: JM8.F6 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_gt0

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp106 Mutation: 115 strains or lines available

References

• Original: J:241305 Celona B, et al., Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. Elife. 2017 Jan 10;6:e19032
• All: 1 reference(s)