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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lep
leptin
MGI:104663
168 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Acacbtm1.2Lowl/Acacbtm1.2Lowl
Lepob/Lepob
involves: 129S6/SvEvTac * FVB/N
increased body weight J:159285
Adigtm1.1(KOMP)Vlcg/Adigtm1.1(KOMP)Vlcg
Lepob/Lepob
B6.Cg-Adigtm1.1(KOMP)Vlcg Lepob
decreased body fat mass J:304292
decreased body weight J:304292
impaired glucose tolerance J:304292
Adipoqtm1Ish/Adipoqtm1Ish
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6J
normal cardiovascular system phenotype J:199264
decreased carbon dioxide production J:199264
decreased energy expenditure J:199264
decreased oxygen consumption J:199264
impaired glucose tolerance J:199264
increased body weight J:199264
increased bone mass J:199264
increased circulating glucose level J:199264
increased susceptibility to weight gain J:199264
increased total fat pad weight J:199264
increased trabecular bone thickness J:199264
increased urine adrenaline level J:199264
Adipoqtm1Pesch/Adipoqtm1Pesch
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6J
impaired glucose tolerance J:107486
Adrb2tm1Kry/Adrb2+
Lepob/Lep+
Tg(Col1a1-cre)1Kry/0
involves: C57BL/6 * C57BL/10J * FVB
decreased circulating glucose level J:145998
increased circulating insulin level J:145998
Ago2tm1.1Tara/Ago2tm1.1Tara
Lepob/Lepob
Tg(Ins2-cre)23Herr/0
involves: 129P2/OlaHsd * C57BL/6J * CBA/J
decreased circulating glucose level J:210552
decreased circulating insulin level J:210552
normal endocrine/exocrine gland phenotype J:210552
improved glucose tolerance J:210552
increased circulating insulin level J:210552
increased pancreatic beta cell mass J:210552
increased pancreatic beta cell number J:210552
Agrptm2(HBEGF)Rpa/Agrp+
Lepob/Lepob
involves: 129S4/SvJaeSor * C57BL/6
abnormal eating behavior J:181947
decreased body temperature J:181947
decreased body weight J:181947
decreased neuron number J:181947
enhanced fertility J:181947
improved glucose tolerance J:181947
increased susceptibility to induced morbidity/mortality J:181947
weight loss J:181947
Akt2tm1.1Mbb/Akt2+
Lepob/Lepob
B6.Cg-Lepob Akt2tm1.1Mbb
decreased body weight J:155432
decreased liver triglyceride level J:155432
decreased liver weight J:155432
Akt2tm1.1Mbb/Akt2tm1.1Mbb
Lepob/Lepob
B6.Cg-Lepob Akt2tm1.1Mbb
abnormal lipid homeostasis J:155432
decreased body weight J:155432
decreased circulating cholesterol level J:155432
decreased liver triglyceride level J:155432
decreased liver weight J:155432
increased circulating glucose level J:155432
increased circulating insulin level J:155432
Akt2tm1.2Mbb/Akt2tm1.2Mbb
Lepob/Lepob
Tg(Alb1-cre)1Khk/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * SJL
abnormal lipid homeostasis J:155432
decreased body weight J:155432
decreased liver triglyceride level J:155432
decreased liver weight J:155432
increased circulating glucose level J:155432
Apobtm2Sgy/Apobtm2Sgy
Apoetm1Unc/Apoetm1Unc
Lepob/Lepob
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
abnormal circulating cholesterol level J:133453
atherosclerotic lesions J:133453
decreased circulating HDL cholesterol level J:133453
hyperglycemia J:133453
hypertension J:133453
impaired glucose tolerance J:133453
increased circulating cholesterol level J:133453
increased circulating free fatty acids level J:133453
increased circulating insulin level J:133453
increased circulating triglyceride level J:133453
increased circulating VLDL cholesterol level J:133453
obese J:133453
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6
abnormal circulating cholesterol level J:133453
atherosclerotic lesions J:133453
decreased circulating HDL cholesterol level J:133453
hypertension J:133453
increased circulating cholesterol level J:133453
increased circulating free fatty acids level J:133453
increased circulating insulin level J:133453
increased circulating LDL cholesterol level J:133453
increased circulating triglyceride level J:133453
obese J:133453
Bglap/Bglap2tm1Kry/Bglap/Bglap2tm1Kry
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/10J
normal endocrine/exocrine gland phenotype J:145998
normal homeostasis/metabolism phenotype J:145998
Bglap/Bglap2tm1Kry/Bglap/Bglap2tm1Kry
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/10J
normal endocrine/exocrine gland phenotype J:145998
normal homeostasis/metabolism phenotype J:145998
Bsxtm1Tre/Bsxtm1Tre
Lepob/Lepob
B6.Cg-Lepob Bsxtm1Tre
abnormal food intake J:122746
decreased core body temperature J:122746
decreased locomotor activity J:122746
hyperglycemia J:122746
increased circulating insulin level J:122746
increased lean body mass J:122746
polyphagia J:122746
reduced female fertility J:122746
C3tm1Hrc/C3tm1Hrc
Lepob/Lepob
involves: 129 * C57BL/6
abnormal energy expenditure J:80546
abnormal glucose homeostasis J:80546
abnormal lipid homeostasis J:80546
abnormal oxygen consumption J:80546
decreased body weight J:80546
decreased circulating insulin level J:80546
increased circulating free fatty acids level J:80546
increased triglyceride level J:80546
polyphagia J:80546
Ccar2tm1Dac/Ccar2tm1Dac
Lepob/Lepob
involves: 129 * C57BL/6J
decreased lean body mass J:228688
impaired glucose tolerance J:228688
increased body weight J:228688
increased total body fat amount J:228688
Cebpatm1Gonz/Cebpatm1Gonz
Lepob/Lepob
Tg(Alb1-cre)1Dlr/0
involves: 129X1/SvJ * C57BL/6J * FVB/N
abnormal fat cell morphology J:93579
abnormal lipid homeostasis J:93579
decreased circulating cholesterol level J:93579
decreased circulating HDL cholesterol level J:93579
decreased circulating insulin level J:93579
decreased circulating LDL cholesterol level J:93579
decreased liver cholesterol level J:93579
decreased liver triglyceride level J:93579
decreased susceptibility to diet-induced hepatic steatosis J:93579
decreased susceptibility to diet-induced obesity J:93579
impaired glucose tolerance J:93579
increased circulating free fatty acids level J:93579
increased circulating glucose level J:93579
increased circulating VLDL cholesterol level J:93579
increased liver glycogen level J:93579
insulin resistance J:93579
Cidectm1Pli/Cidectm1Pli
Lepob/Lepob
involves: C57BL/10J
abnormal adipose tissue amount J:140122
abnormal body weight J:140122
abnormal gonadal fat pad morphology J:140122
decreased circulating free fatty acids level J:140122
decreased circulating triglyceride level J:140122
improved glucose tolerance J:140122
increased insulin sensitivity J:140122
Clockm1Jt/Clockm1Jt
Lepob/Lepob
involves: BALB/c * C57BL/6 * C57BL/6J * Jcl:ICR
decreased circulating glucose level J:135847
decreased circulating insulin level J:135847
increased body weight J:135847
increased circulating cholesterol level J:135847
increased circulating free fatty acids level J:135847
increased circulating glucose level J:135847
increased circulating insulin level J:135847
increased circulating triglyceride level J:135847
increased fat cell size J:135847
Cnot3tm1.1Tya/Cnot3+
Lepob/Lepob
involves: 129P2/OlaHsd * C57BL/6J
normal behavior/neurological phenotype J:180033
decreased body weight J:180033
decreased respiratory quotient J:180033
improved glucose tolerance J:180033
increased insulin sensitivity J:180033
increased oxygen consumption J:180033
Dbmc1BTBR/Dbmc1BTBR
Lepob/Lepob
involves: BTBR * C57BL/6J
abnormal enzyme/coenzyme level J:119260
Dbmc1BTBR/Dbmc1C57BL/6J
Lepob/Lepob
involves: BTBR * C57BL/6J
abnormal enzyme/coenzyme level J:119260
Dbmc2BTBR/Dbmc2BTBR
Lepob/Lepob
involves: BTBR * C57BL/6J
abnormal enzyme/coenzyme level J:119260
Dbmc2BTBR/Dbmc2C57BL/6J
Lepob/Lepob
involves: BTBR * C57BL/6J
abnormal enzyme/coenzyme level J:119260
Dbmc3BTBR/Dbmc3C57BL/6J
Lepob/Lepob
involves: BTBR * C57BL/6J
abnormal enzyme/coenzyme level J:119260
Dbmc3C57BL/6J/Dbmc3C57BL/6J
Lepob/Lepob
involves: BTBR * C57BL/6J
abnormal enzyme/coenzyme level J:119260
Dmbx1tm1Sse/Dmbx1tm1Sse
Lepob/Lepob
involves: ICR
abnormal body weight J:125193
abnormal circulating glucose level J:125193
Fabp4tm1Brsp/Fabp4tm1Brsp
Fabp5tm1Hota/Fabp5tm1Hota
Lepob/Lepob
B6.Cg-Fabp4tm1Brsp Fabp5tm1Hota Lepob
abnormal gluconeogenesis J:111878
abnormal glucose homeostasis J:111878
abnormal glycogen homeostasis J:111878
decreased circulating cholesterol level J:111878
decreased circulating glucose level J:111878
decreased circulating insulin level J:111878
decreased circulating triglyceride level J:111878
decreased liver triglyceride level J:111878
decreased susceptibility to hepatic steatosis J:111878
improved glucose tolerance J:111878
increased adipocyte glucose uptake J:111878
increased body weight J:111878
increased fatty acids level J:111878
increased insulin sensitivity J:111878
increased muscle cell glucose uptake J:111878
increased white adipose tissue amount J:111878
small liver J:111878
Fabp4tm1Brsp/Fabp4tm1Brsp
Lepob/Lepob
B6.Cg-Fabp4tm1Brsp Lepob
improved glucose tolerance J:111878
increased insulin sensitivity J:111878
Fabp5tm1Hota/Fabp5tm1Hota
Lepob/Lepob
B6.Cg-Fabp5tm1Hota Lepob
improved glucose tolerance J:111878
increased insulin sensitivity J:111878
Fabp5tm1Hota/Fabp5tm1Hota
Lepob/Lepob
involves: 129 * C57BL/6J * C57BL/10J * SJL
decreased circulating glucose level J:81609
improved glucose tolerance J:81609
increased circulating insulin level J:81609
increased insulin sensitivity J:81609
obese J:81609
Fitm2tm1.1Dls/Fitm2tm1.1Dls
Lepob/Lepob
Tg(Fabp4-cre)1Rev/?
involves: 129S6/SvEvTac * C57BL/6J
decreased body weight J:212437
decreased subcutaneous adipose tissue amount J:212437
decreased white adipose tissue amount J:212437
Ftotm1Urt/Ftotm1Urt
Lepob/Lepob
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal adipose tissue morphology J:219118
decreased body length J:219118
decreased locomotor activity J:219118
enlarged pancreatic islets J:219118
hepatic steatosis J:219118
increased body weight J:219118
increased fat cell size J:219118
increased gonadal fat pad weight J:219118
increased inguinal fat pad weight J:219118
increased interscapular fat pad weight J:219118
increased liver weight J:219118
increased percent body fat/body weight J:219118
insulin resistance J:219118
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Lepob/Lepob
Tg(Adipoq-cre)1Evdr/0
involves: 129S4/SvJaeSor * C57BL/6J * FVB/NJ
normal adipose tissue phenotype J:237232
hyperglycemia J:237232
Hmga2tm1Cha/Hmga2+
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6J
decreased body size J:61493
decreased body weight J:61493
Hmga2tm1Cha/Hmga2tm1Cha
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6J
abnormal body weight J:61493
abnormal fat pad morphology J:61493
decreased body size J:61493
decreased inguinal fat pad weight J:61493
decreased mesenteric fat pad weight J:61493
Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J
Lepob/Lepob
B6.Cg-Ildr2Dbsm1-DBA/2J Lepob
decreased circulating insulin level J:138216
decreased pancreatic beta cell mass J:138216
hyperglycemia J:138216
impaired glucose tolerance J:138216
Kittm1Rosay/Kit+
Lepob/Lepob
involves: 129S7/SvEvBrd * C57BL/6J
abnormal interstitial cell of Cajal morphology J:168676
hyperglycemia J:168676
obese J:168676
white spotting J:168676
Ldlrtm1Her/Ldlr+
Lepob/Lepob
B6.Cg-Lepob Ldlrtm1Her
increased circulating cholesterol level J:72027
increased circulating HDL cholesterol level J:72027
increased liver cholesterol level J:72027
increased liver triglyceride level J:72027
Ldlrtm1Her/Ldlrtm1Her
Lepob/Lepob
B6.Cg-Lepob Ldlrtm1Her
abnormal circulating cholesterol level J:72027
atherosclerotic lesions J:72027
hyperlipidemia J:72027
increased circulating cholesterol level J:72027
increased circulating HDL cholesterol level J:72027
increased circulating triglyceride level J:72027
increased liver cholesterol level J:72027
increased liver triglyceride level J:72027
Lepob/Lep+
Npy4rtm1.1Hhz/Npy4rtm1.1Hhz
involves: 129X1/SvJ * C57BL/6
increased body weight J:76479
increased white adipose tissue amount J:76479
Lepob/Lep+
Tg(Apoe-Lepr)1Kry/0
involves: C57BL/6J
increased bone mass J:88655
increased total body fat amount J:88655
Lepob/Lepob
Lgals12tm1Ftl/Lgals12+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
decreased inguinal fat pad weight J:180097
Lepob/Lepob
Lgals12tm1Ftl/Lgals12tm1Ftl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
decreased body weight J:180097
decreased gonadal fat pad weight J:180097
decreased inguinal fat pad weight J:180097
Lepob/Lepob
Mapk8tm1Wag/Mapk8tm1Wag
B6.Cg-Lepob Mapk8tm1Wag
decreased body weight J:80452
decreased circulating glucose level J:80452
decreased circulating insulin level J:80452
Lepob/Lepob
Mir375tm1Stf/Mir375tm1Stf
B6.Cg-Mir375tm1Stf Lepob
abnormal gluconeogenesis J:147572
decreased body size J:147572
decreased circulating insulin level J:147572
decreased pancreatic beta cell mass J:147572
decreased pancreatic beta cell number J:147572
increased circulating glucose level J:147572
increased pancreatic alpha cell number J:147572
polydipsia J:147572
polyuria J:147572
Lepob/Lepob
Mogat1tm1Far/Mogat1tm1Far
involves: 129S4/SvJae
normal homeostasis/metabolism phenotype J:231617
increased circulating cholesterol level J:231617
increased circulating glucose level J:231617
increased circulating insulin level J:231617
increased circulating triglyceride level J:231617
increased liver triglyceride level J:231617
insulin resistance J:231617
Lepob/Lepob
Nfe2l2tm1.1Jgpi/Nfe2l2tm1.1Jgpi
Tg(Fabp4-cre)1Rev/0
involves: C57BL/6
abnormal white fat cell morphology J:208590
decreased white adipose tissue amount J:208590
normal homeostasis/metabolism phenotype J:208590
increased circulating glucose level J:208590
increased circulating triglyceride level J:208590
insulin resistance J:208590
Lepob/Lepob
Nfe2l2tm1Mym/Nfe2l2tm1Mym
B6.Cg-Nfe2l2tm1Mym Lepob
abnormal adipose tissue development J:208590
abnormal urine color J:208590
abnormal white fat cell morphology J:208590
decreased body weight J:208590
decreased food intake J:208590
decreased liver triglyceride level J:208590
decreased susceptibility to weight gain J:208590
decreased white adipose tissue amount J:208590
hepatic steatosis J:208590
normal homeostasis/metabolism phenotype J:208590
hyperglycemia J:208590
increased circulating triglyceride level J:208590
insulin resistance J:208590
premature death J:208590
Lepob/Lepob
Npy2rtm1.1Hhz/Npy2rtm1.1Hhz
involves: 129X1/SvJ * C57BL/6
abnormal adipose tissue amount J:107169
abnormal circulating glucose level J:107169
abnormal circulating insulin level J:107169
abnormal intestine morphology J:107169
decreased circulating corticosterone level J:107169
decreased circulating testosterone level J:107169
decreased epididymal fat pad weight J:107169
decreased lean body mass J:107169
decreased mesenteric fat pad weight J:107169
decreased testis weight J:107169
female infertility J:76479
increased body weight J:107169
increased circulating cholesterol level J:107169
increased circulating triglyceride level J:107169
increased kidney weight J:107169
increased liver weight J:107169
increased pancreas weight J:107169
male infertility J:76479, J:107169
polyphagia J:107169
Lepob/Lepob
Npy2rtm1Pern/Npy2rtm1Pern
involves: 129 * BALB/c * C57BL/10J
decreased body weight J:102651
decreased circulating free fatty acids level J:102651
decreased circulating glucose level J:102651
decreased circulating LDL cholesterol level J:102651
increased circulating cholesterol level J:102651
increased circulating HDL cholesterol level J:102651
increased triglyceride level J:102651
Lepob/Lepob
Npy4rtm1.1Hhz/Npy4rtm1.1Hhz
involves: 129X1/SvJ * C57BL/6
abnormal adipose tissue amount J:76479
abnormal branching of the mammary ductal tree J:76479
abnormal circulating testosterone level J:76479
abnormal estrous cycle J:76479
abnormal ovarian follicle morphology J:76479
abnormal vagina orifice morphology J:76479
enhanced fertility J:76479
normal homeostasis/metabolism phenotype J:76479
increased circulating corticosterone level J:76479
increased Leydig cell number J:76479
increased seminal vesicle weight J:76479
increased sperm number J:76479
increased susceptibility to weight gain J:76479
Lepob/Lepob
Npy5rtm1Rpa/Npy5rtm1Rpa
involves: 129S7/SvEvBrd * C57BL/6
abnormal body weight J:87803
increased total fat pad weight J:87803
obese J:87803
polyphagia J:87803
Lepob/Lepob
Nr1i3tm1Dgen/Nr1i3tm1Dgen
B6.Cg-Nr1i3tm1Dgen Lepob
decreased circulating triglyceride level J:149091
Lepob/Lepob
Plin4tm1Vlcg/Plin4tm1Vlcg
involves: C57BL/6J
decreased cardiac muscle triglyceride level J:195987
Lepob/Lepob
Pmchtm1.1(HBEGF)Rpa/Pmch+
B6.Cg-Lepob Pmchtm1.1(DTR)Rpa
abnormal postnatal growth J:181947
normal behavior/neurological phenotype J:181947
decreased body weight J:181947
decreased neuron number J:181947
female infertility J:181947
improved glucose tolerance J:181947
reduced male fertility J:181947
Lepob/Lepob
Pmchtm1Emf/Pmchtm1Emf
involves: 129S4/SvJae * C57BL/6
abnormal adipose tissue amount J:85176
abnormal circulating corticosterone level J:85176
abnormal glucose homeostasis J:85176
abnormal glucose tolerance J:85176
decreased circulating glucose level J:85176
decreased locomotor activity J:85176
hepatic steatosis J:85176
impaired adaptive thermogenesis J:85176
increased body weight J:85176
increased circulating insulin level J:85176
increased food intake J:85176
increased oxygen consumption J:85176
Lepob/Lepob
Ppargtm1Avp/Pparg+
involves: 129S2/SvPas * C57BL/6
abnormal glucose homeostasis J:116568
abnormal gonadal fat pad morphology J:116568
abnormal skeletal muscle morphology J:116568
abnormal white adipose tissue amount J:116568
decreased body fat mass J:116568
decreased body weight J:116568
decreased circulating adiponectin level J:116568
decreased fat cell size J:116568
hepatic steatosis J:116568
increased circulating glucose level J:116568
increased circulating insulin level J:116568
increased circulating triglyceride level J:116568
increased liver weight J:116568
insulin resistance J:116568
polyphagia J:116568
Lepob/Lepob
Ppargtm2Avp/Ppargtm2Avp
involves: 129 * C57BL/6
abnormal fat cell morphology J:121534
abnormal glucose homeostasis J:121534
abnormal insulin secretion J:121534
abnormal lipid homeostasis J:121534
abnormal liver morphology J:121534
abnormal locomotor behavior J:121534
abnormal pancreatic islet morphology J:121534
abnormal skeletal muscle morphology J:121534
decreased circulating adiponectin level J:121534
decreased circulating insulin level J:121534
decreased liver triglyceride level J:121534
decreased locomotor activity J:121534
decreased respiratory quotient J:121534
decreased triglyceride level J:121534
disorganized pancreatic islets J:121534
normal endocrine/exocrine gland phenotype J:121534
normal growth/size/body region phenotype J:121534
hepatic steatosis J:121534
hyperglycemia J:121534
increased circulating free fatty acids level J:121534
increased circulating glucose level J:121534
increased circulating insulin level J:121534
increased circulating triglyceride level J:121534
increased fluid intake J:121534
increased percent body fat/body weight J:121534
increased urine glucose level J:121534
insulin resistance J:121534
oxidative stress J:121534
polyphagia J:121534
Lepob/Lepob
Ptprvtm1Asmi/Ptprv+
involves: 129P2/OlaHsd * C57BL/10J
increased circulating insulin level J:145998
Lepob/Lepob
Ptprvtm1Asmi/Ptprvtm1Asmi
involves: 129P2/OlaHsd * C57BL/10J
decreased circulating glucose level J:145998
improved glucose tolerance J:145998
increased circulating insulin level J:145998
Lepob/Lepob
Rcan2tm1Ypt/Rcan2tm1Ypt
involves: 129 * C57BL/6
decreased body weight J:169558
decreased epididymal fat pad weight J:169558
decreased liver weight J:169558
decreased retroperitoneal fat pad weight J:169558
Lepob/Lepob
Serpine1tm1Mlg/Serpine1tm1Mlg
involves: 129S2/SvPas * C57BL/6
abnormal tumor necrosis factor level J:70695
impaired glucose tolerance J:70695
increased circulating insulin level J:70695
Lepob/Lepob
Sesn2Gt(RRJ141)Byg/Sesn2Gt(RRJ141)Byg
involves: 129P2/OlaHsd * C57BL/6
decreased fatty acid beta-oxidation J:189021
hepatic steatosis J:189021
impaired glucose tolerance J:189021
increased circulating glucose level J:189021
increased liver triglyceride level J:189021
increased urine glucose level J:189021
insulin resistance J:189021
Lepob/Lepob
Steap4tm1Dgen/Steap4tm1Dgen
involves: 129P2/OlaHsd
hepatic steatosis J:187736
increased circulating glucose level J:187736
increased percent body fat/body weight J:187736
Lepob/Lepob
Stxbp5lT2dm1/Stxbp5lT2dm1
B6.Cg-Lepob Chr 16BTNTTF
decreased circulating insulin level J:178002
increased circulating glucose level J:178002
Lepob/Lepob
Stxbp5lT2dm1/Stxbp5lT2dm1
T2dm2C57BL/6J/T2dm2C57BL/6J
involves: BTBR * C57BL/6J
hyperglycemia J:65486
Lepob/Lepob
T2dm2BTBR/T2dm2BTBR
involves: BTBR * C57BL/6J
increased circulating insulin level J:65486
Lepob/Lepob
T2dm2BTBR/T2dm2C57BL/6J
involves: BTBR * C57BL/6J
increased circulating insulin level J:65486
Lepob/Lepob
Tg(Eno2-Pomc)1Mobb/?
involves: C3H * C57BL/6
abnormal body size J:86303
abnormal body temperature J:86303
abnormal body weight J:86303
abnormal fatty acids level J:86303
abnormal food intake J:86303
abnormal liver size J:86303
normal homeostasis/metabolism phenotype J:86303
Lepob/Lepob
Tg(Ins2-Mir184)4Mnpy/0
involves: C57BL/10J
decreased body weight J:210552
decreased circulating insulin level J:210552
decreased insulin secretion J:210552
decreased pancreatic beta cell mass J:210552
hyperglycemia J:210552
weight loss J:210552
Lepob/Lepob
Tg(Ins2-rtTA)2Efr/0
Tg(tetO-Mir184)#Mnpy/0
involves: C57BL/6 * CBA
decreased circulating insulin level J:210552
increased circulating glucose level J:210552
Lepob/Lepob
Tg(Myh6-Med13)1Eno/0
involves: C57BL/6
decreased body weight J:186193
improved glucose tolerance J:186193
Lepob/Lepob
Tg(Pmch-ATXN3*)3Rck/0
involves: C57BL/6J * FVB/NJ
abnormal fertility/fecundity J:104264
abnormal maternal nurturing J:104264
decreased body weight J:104264
decreased circulating glucose level J:104264
normal liver/biliary system phenotype J:104264
Lepob/Lepob
Tg(tetO-Xbp1_is)#Pesch/0
Tg(Adipoq-rtTA)2Zvw/0
involves: C57BL/6 * C57BL/6N * FVB/N
decreased susceptibility to diet-induced obesity J:260830
Lepob/Lepob
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tnfrsf1btm1Imx/Tnfrsf1btm1Imx
involves: 129S7/SvEvBrd * C57BL/6
abnormal adipose tissue morphology J:55722
abnormal metabolism J:55722
decreased circulating insulin level J:55722
Lepob/Lepob
Ucp1tm1Kz/Ucp1tm1Kz
involves: 129S2/SvPas * C57BL/6
decreased respiratory quotient J:129662
impaired adaptive thermogenesis J:129662
increased oxygen consumption J:129662
weight loss J:129662
Npbwr1tm1Rck/Npbwr1tm1Rck
Lepob/Lepob
involves: 129P/Ola * C57BL/6J
obese J:94820

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory