Tg(Eno2-Pomc)1Mobb
Transgene Detail

Summary

• Symbol: Tg(Eno2-Pomc)1Mobb
• Name: transgene insertion 1, Charles V Mobbs
• MGI ID: MGI:4420545
• Synonyms: Pomc^tg
• Transgene: Tg(Eno2-Pomc)1Mobb Location: unknown
• Alliance: Tg(Eno2-Pomc)1Mobb page

Transgene origin

• Strain of Origin: (C57BL/6J x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-Pomc)1Mobb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pomc (MGI:97742)

• Mutation details: A mouse Pomc cDNA was placed under the control of the neuron specific enolase promoter which induces increased expression in neurons. Two founder lines were created but only one is reported. (J:86303)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:86303 Mizuno TM, et al., Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice. Diabetes. 2003 Nov;52(11):2675-83
• All: 1 reference(s)