Fabp5^tm1Hota
Targeted Allele Detail

Summary

• Symbol: Fabp5^tm1Hota
• Name: fatty acid binding protein 5, epidermal; targeted mutation 1, Gokhan S Hotamisligil
• MGI ID: MGI:2450172
• Synonyms: E-FABP^-, mal1^-
• Gene: Fabp5 Location: Chr3:10077645-10081670 bp, + strand Genetic Position: Chr3, 2.47 cM, cytoband A1-A3
• Alliance: Fabp5^tm1Hota page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81609
• Parent Cell Line: WW6 (ES Cell)
• Strain of Origin: STOCK 129/Sv and C57BL/6J and SJL

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 1 was disrupted by the insertion of a neomycin selection cassette. No transcript or protein was detected by Northern or Western blot analysis. (J:81609)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fabp5 Mutation: 14 strains or lines available

References

• Original: J:81609 Maeda K, et al., Role of the fatty acid binding protein mal1 in obesity and insulin resistance. Diabetes. 2003 Feb;52(2):300-7
• All: 36 reference(s)