Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Grin2b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GRIN2B
- Mouse genes Grin2b
- Rat genes Grin2b
- Zfish genes grin2bb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grin2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Grin2b	IPI	RGD:70487	Rat	PMID:20007479\|RGD:4107027
Molecular Function	GO:0005262	calcium channel activity	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:12816890
Molecular Function	GO:0050839	cell adhesion molecule binding	Grin2b	IPI	RGD:2505	Rat	PMID:16540568\|RGD:1642315
Molecular Function	GO:0050839	cell adhesion molecule binding	Grin2b	IPI	RGD:68423	Rat	PMID:16540568\|RGD:1642315
Molecular Function	GO:0050839	cell adhesion molecule binding	Grin2b	IPI	RGD:68424	Rat	PMID:16540568\|RGD:1642315
Molecular Function	GO:0031749	D2 dopamine receptor binding	Grin2b	IPI	RGD:2520	Rat	PMID:17145509\|RGD:1642312
Molecular Function	GO:0005234	extracellularly glutamate-gated ion channel activity	Grin2b	IDA		Rat	PMID:1350383\|RGD:727540
Molecular Function	GO:0016595	glutamate binding	Grin2b	IDA		Rat	PMID:24876489\|RGD:13432263
Molecular Function	GO:0022849	glutamate-gated calcium ion channel activity	GRIN2B	IDA		Human	PMID:26875626
Molecular Function	GO:0022849	glutamate-gated calcium ion channel activity	GRIN2B	IMP		Human	PMID:27839871
Molecular Function	GO:0016594	glycine binding	GRIN2B	IDA		Human	PMID:17047094
Molecular Function	GO:1901363	heterocyclic compound binding	Grin2b	IDA		Rat	PMID:20082612\|RGD:4107023
Molecular Function	GO:0005149	interleukin-1 receptor binding	Grin2b	IPI	RGD:2892	Rat	PMID:21314939\|RGD:5508726
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Grin2b	IDA		Rat	PMID:16477151\|RGD:1642190
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Grin2b	IPI	RGD:2736	Rat	PMID:19298817\|RGD:2326007
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIN2B	IDA		Human	PMID:19666514
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIN2B	IMP		Human	PMID:19666514
Molecular Function	GO:0005261	monoatomic cation channel activity	Grin2b	IGI	MGI:MGI:95819	Mouse	PMID:7531804
Molecular Function	GO:0042165	neurotransmitter binding	Grin2b	IDA		Rat	PMID:16477151\|RGD:1642190
Molecular Function	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Grin2b	IMP		Rat	PMID:15987933\|RGD:12050132
Molecular Function	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	Grin2b	IMP		Mouse	MGI:MGI:4358803\|PMID:19726645
Molecular Function	GO:0004972	NMDA glutamate receptor activity	GRIN2B	IDA		Human	PMID:26919761
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IGI	MGI:MGI:95819	Mouse	PMID:7531804
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IMP	MGI:MGI:1928293	Mouse	PMID:9458051
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:12816890
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:10634899
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IMP		Mouse	PMID:12832518
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IGI	MGI:MGI:95823	Mouse	PMID:12832518
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IGI	MGI:MGI:95819	Mouse	PMID:1377365
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IDA		Rat	PMID:1350383\|RGD:727540
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IDA		Rat	PMID:16477151\|RGD:1642190
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IDA		Rat	PMID:24876489\|RGD:13432263
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2b	IDA		Rat	PMID:28384476\|RGD:13432313
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:P31016	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:P78352	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q62936	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q05586	Human	PMID:17047094
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q8TCU5	Human	PMID:17997397
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:P62139	Human	PMID:19453375
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q9UQM7	Human	PMID:19453375
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:P78352	Human	PMID:20018661
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q12959	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q9UQM7	Human	PMID:28130356
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	GRIN2B	IPI	UniProtKB:Q05586-1	Human	PMID:34321660
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:6092779\|PMID:28671696
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:5314458\|PMID:22234183
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798	Mouse	MGI:MGI:5314458\|PMID:22234183
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35438	Mouse	MGI:MGI:6694380\|PMID:32033586
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:4457467\|PMID:20141836
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798\|UniProtKB:P35438\|UniProtKB:Q80YE7	Mouse	MGI:MGI:4457467\|PMID:20141836
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798\|UniProtKB:P17426\|UniProtKB:Q9JI91	Mouse	MGI:MGI:3701026\|PMID:16710293
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3701026\|PMID:16710293
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q8VD75	Mouse	MGI:MGI:3703280\|PMID:17329427
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P61809	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3838437\|PMID:19240213
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q8R4I7	Mouse	MGI:MGI:3836361\|PMID:19243221
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q9QYR6	Mouse	MGI:MGI:5703671\|PMID:26609151
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:1860431\|PMID:10862698
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3836361\|PMID:19243221
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798\|UniProtKB:P35438\|UniProtKB:Q9JI91	Mouse	MGI:MGI:1860431\|PMID:10862698
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:5903931\|PMID:28604739
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3764767\|PMID:17950729
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35438	Mouse	MGI:MGI:3836361\|PMID:19243221
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q9DCF1	Mouse	MGI:MGI:6370252\|PMID:31424425
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3694290\|PMID:16332682
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798	Mouse	MGI:MGI:5560492\|PMID:24725413
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35438	Mouse	MGI:MGI:6788519\|PMID:34646371
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:4359331\|PMID:19455133
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:P35438	Mouse	PMID:9003035
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:P35438	Mouse	PMID:8595214
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:P61809	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:Q9WU22	Mouse	PMID:33158444
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:P49615	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:Q62108	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:P35438	Mouse	PMID:16554481
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:000045531	Mouse	PMID:21880917
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:Q9QVP4	Mouse	PMID:15663482
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:Q61120	Mouse	PMID:15716419
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	PR:O35350	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P28818	Rat	PMID:14622581\|RGD:8554730
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	RGD:620314	Rat	PMID:15010472\|RGD:1599256
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798	Rat	PMID:16120608\|RGD:2314407
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62936	Rat	PMID:16427633\|RGD:7241543
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q460M5	Rat	PMID:16495444\|RGD:8554054
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P31016	Rat	PMID:16990796\|RGD:8553335
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35439	Rat	PMID:19243221\|RGD:13432354
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q8R4I7	Rat	PMID:19243221\|RGD:13432354
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	RGD:70991	Rat	PMID:19298817\|RGD:2326007
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	RGD:70993	Rat	PMID:19298817\|RGD:2326007
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	RGD:621011	Rat	PMID:20171009\|RGD:4107021
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11275	Rat	PMID:20461055\|RGD:8554257
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:A0A1L8F5J9-8	Rat	PMID:21677647\|RGD:13432283
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35439-7	Rat	PMID:21677647\|RGD:13432283
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P31016	Rat	PMID:23567299\|RGD:8554569
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11275	Rat	PMID:24591565\|RGD:10047343
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35439	Rat	PMID:24876489\|RGD:13432263
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:A0A1L8F5J9-8	Rat	PMID:27135925\|RGD:13432235
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35439	Rat	PMID:27135925\|RGD:13432235
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P11798	Rat	PMID:28130356\|RGD:150521634
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P31016	Rat	PMID:7569905\|RGD:8554530
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P31016	Rat	PMID:8601796\|RGD:8554595
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62936	Rat	PMID:8702950\|RGD:8553561
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P35439	Rat	PMID:8780649\|RGD:8553636
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q62936	Rat	PMID:8780649\|RGD:8553636
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:Q63ZW7	Rat	PMID:9647694\|RGD:8553765
Molecular Function	GO:0005515	protein binding	Grin2b	IPI	UniProtKB:P31016	Rat	PMID:9786987\|RGD:8553274
Molecular Function	GO:0044877	protein-containing complex binding	Grin2b	IDA		Rat	PMID:1350383\|RGD:727540
Molecular Function	GO:0044877	protein-containing complex binding	Grin2b	IDA		Rat	PMID:21544205\|RGD:7241533
Molecular Function	GO:0097110	scaffold protein binding	Grin2b	IPI	RGD:68424	Rat	PMID:17270176\|RGD:13432036
Molecular Function	GO:0005102	signaling receptor binding	Grin2b	IPI	RGD:2520	Rat	PMID:17145509\|RGD:1642312
Molecular Function	GO:0036094	small molecule binding	Grin2b	IPI	CHEBI:93829	Rat	PMID:20082612\|RGD:4107023
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Grin2b	IDA		Rat	PMID:12160751\|RGD:13792531
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Grin2b	IMP		Rat	PMID:12160751\|RGD:13792531
Molecular Function	GO:0008270	zinc ion binding	Grin2b	IDA		Rat	PMID:19910922\|RGD:8553268
Cellular Component	GO:0097440	apical dendrite	Grin2b	IDA		Rat	PMID:12654351\|RGD:13432041
Cellular Component	GO:0009986	cell surface	Grin2b	IDA		Mouse	MGI:MGI:5703671\|PMID:26609151
Cellular Component	GO:0009986	cell surface	Grin2b	IDA		Mouse	MGI:MGI:3765383\|PMID:17229826
Cellular Component	GO:0009986	cell surface	Grin2b	IMP		Mouse	MGI:MGI:3765383\|PMID:17229826
Cellular Component	GO:0009986	cell surface	Grin2b	IDA		Mouse	PMID:21880917
Cellular Component	GO:0009986	cell surface	Grin2b	IDA		Rat	PMID:17526495\|RGD:13506268
Cellular Component	GO:0009986	cell surface	Grin2b	IDA		Rat	PMID:22442066\|RGD:13210761
Cellular Component	GO:0005737	cytoplasm	Grin2b	IDA		Rat	PMID:17526495\|RGD:13506268
Cellular Component	GO:0044307	dendritic branch	Grin2b	IDA		Rat	PMID:22442066\|RGD:13210761
Cellular Component	GO:0043197	dendritic spine	Grin2b	IDA		Rat	PMID:17207780\|RGD:1642304
Cellular Component	GO:0098978	glutamatergic synapse	Grin2b	IDA		Mouse	PMID:19726645
Cellular Component	GO:0098978	glutamatergic synapse	Grin2b	IDA		Rat	PMID:12160751\|RGD:13792531
Cellular Component	GO:0098978	glutamatergic synapse	Grin2b	IMP		Rat	PMID:12160751\|RGD:13792531
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Grin2b	IDA		Rat	PMID:23159309\|RGD:13702288
Cellular Component	GO:0005770	late endosome	Grin2b	IDA		Mouse	MGI:MGI:6370252\|PMID:31424425
Cellular Component	GO:0005764	lysosome	Grin2b	IDA		Mouse	MGI:MGI:6370252\|PMID:31424425
Cellular Component	GO:0016020	membrane	Grin2b	IDA		Mouse	PMID:9003035
Cellular Component	GO:0016020	membrane	Grin2b	IDA		Mouse	PMID:33158444
Cellular Component	GO:0016020	membrane	Grin2b	IDA		Mouse	PMID:10846156
Cellular Component	GO:0016020	membrane	Grin2b	IDA		Mouse	PMID:8840015
Cellular Component	GO:0043005	neuron projection	Grin2b	IDA		Mouse	MGI:MGI:5320264\|PMID:21795692
Cellular Component	GO:0043005	neuron projection	Grin2b	IDA		Rat	PMID:12738960\|RGD:8554028
Cellular Component	GO:0043025	neuronal cell body	Grin2b	IDA		Rat	PMID:22442066\|RGD:13210761
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN2B	IDA		Human	PMID:10480938
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN2B	IDA		Human	PMID:17047094
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN2B	IDA		Human	PMID:26875626
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN2B	IDA		Human	PMID:26919761
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2b	IPI	PR:P35438	Mouse	PMID:9003035
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2b	IDA		Rat	PMID:1350383\|RGD:727540
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2b	IDA		Rat	PMID:16477151\|RGD:1642190
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2b	IDA		Rat	PMID:24876489\|RGD:13432263
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2b	IDA		Rat	PMID:28384476\|RGD:13432313
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2b	IDA		Rat	PMID:8702950\|RGD:8553561
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Grin2b	IDA		Rat	PMID:19666514\|RGD:2325961
Cellular Component	GO:0005886	plasma membrane	GRIN2B	IDA		Human	PMID:26875626
Cellular Component	GO:0005886	plasma membrane	GRIN2B	IDA		Human	PMID:26919761
Cellular Component	GO:0005886	plasma membrane	GRIN2B	IDA		Human	PMID:27839871
Cellular Component	GO:0005886	plasma membrane	Grin2b	IDA		Rat	PMID:17207582\|RGD:152995278
Cellular Component	GO:0005886	plasma membrane	Grin2b	IDA		Rat	PMID:24876489\|RGD:13432263
Cellular Component	GO:0005886	plasma membrane	Grin2b	IDA		Rat	PMID:28384476\|RGD:13432313
Cellular Component	GO:0005886	plasma membrane	Grin2b	IDA		Rat	PMID:27881773\|RGD:25671385
Cellular Component	GO:0098794	postsynapse	Grin2b	IDA		Mouse	MGI:MGI:5816444\|PMID:21144999
Cellular Component	GO:0098794	postsynapse	Grin2b	IDA		Mouse	PMID:33158444
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	MGI:MGI:5703671\|PMID:26609151
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	MGI:MGI:5286805\|PMID:21664258
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	PMID:29490264
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	PMID:15748150
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	PMID:16190898
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	PMID:21880917
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	PMID:17114649
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Mouse	PMID:24069373
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Rat	PMID:17145509\|RGD:1642312
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Rat	PMID:17207780\|RGD:1642304
Cellular Component	GO:0014069	postsynaptic density	Grin2b	IDA		Rat	PMID:9509416\|RGD:13432267
Cellular Component	GO:0098839	postsynaptic density membrane	Grin2b	IDA		Mouse	PMID:19726645
Cellular Component	GO:0098839	postsynaptic density membrane	Grin2b	IDA		Rat	PMID:23159309\|RGD:13702288
Cellular Component	GO:0045211	postsynaptic membrane	Grin2b	IDA		Mouse	PMID:12890763
Cellular Component	GO:0045211	postsynaptic membrane	Grin2b	IDA		Mouse	PMID:12676993
Cellular Component	GO:0048787	presynaptic active zone membrane	Grin2b	IDA		Rat	PMID:23159309\|RGD:13702288
Cellular Component	GO:0042734	presynaptic membrane	Grin2b	IDA		Mouse	MGI:MGI:3689798\|PMID:16157280
Cellular Component	GO:0042734	presynaptic membrane	Grin2b	IDA		Rat	PMID:19666514\|RGD:2325961
Cellular Component	GO:0042734	presynaptic membrane	Grin2b	IDA		Rat	PMID:16157280\|RGD:8553269
Cellular Component	GO:0045202	synapse	Grin2b	IDA		Mouse	PMID:14645471
Cellular Component	GO:0045202	synapse	Grin2b	IDA		Mouse	PMID:33158444
Cellular Component	GO:0045202	synapse	Grin2b	IDA		Mouse	PMID:16710293
Cellular Component	GO:0045202	synapse	Grin2b	IDA		Rat	PMID:12732245\|RGD:8553787
Cellular Component	GO:0043083	synaptic cleft	Grin2b	IDA		Rat	PMID:17207780\|RGD:1642304
Cellular Component	GO:0097060	synaptic membrane	Grin2b	IDA		Mouse	MGI:MGI:5703671\|PMID:26609151
Cellular Component	GO:0008021	synaptic vesicle	Grin2b	IDA		Mouse	PMID:10846156
Cellular Component	GO:0008021	synaptic vesicle	Grin2b	IDA		Mouse	PMID:20418887
Cellular Component	GO:0043195	terminal bouton	Grin2b	IDA		Rat	PMID:19666514\|RGD:2325961
Cellular Component	GO:0030018	Z disc	Grin2b	IDA		Rat	PMID:15010472\|RGD:1599256
Biological Process	GO:0001508	action potential	Grin2b	IMP		Rat	PMID:16904707\|RGD:1642207
Biological Process	GO:0001508	action potential	Grin2b	IMP		Rat	PMID:17655746\|RGD:1642204
Biological Process	GO:0008306	associative learning	Grin2b	IMP		Rat	PMID:17328778\|RGD:1642305
Biological Process	GO:0001662	behavioral fear response	Grin2b	IMP	MGI:MGI:3701351	Mouse	PMID:16710293
Biological Process	GO:0001662	behavioral fear response	Grin2b	IMP		Rat	PMID:21285873\|RGD:13210750
Biological Process	GO:0048266	behavioral response to pain	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:11711849
Biological Process	GO:0097553	calcium ion transmembrane import into cytosol	GRIN2B	IDA		Human	PMID:26875626
Biological Process	GO:0097553	calcium ion transmembrane import into cytosol	GRIN2B	IMP		Human	PMID:27839871
Biological Process	GO:0006816	calcium ion transport	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:12816890
Biological Process	GO:0006816	calcium ion transport	Grin2b	IMP		Mouse	PMID:16045501
Biological Process	GO:0071230	cellular response to amino acid stimulus	Grin2b	IEP		Rat	PMID:20336776\|RGD:4107019
Biological Process	GO:0071230	cellular response to amino acid stimulus	Grin2b	IEP		Rat	PMID:20526740\|RGD:2325861
Biological Process	GO:0071386	cellular response to corticosterone stimulus	Grin2b	IEP		Rat	PMID:19540859\|RGD:13432032
Biological Process	GO:1904644	cellular response to curcumin	Grin2b	IEP		Rat	PMID:19540859\|RGD:13432032
Biological Process	GO:0071359	cellular response to dsRNA	Grin2b	IEP		Rat	PMID:19958814\|RGD:2325933
Biological Process	GO:1904322	cellular response to forskolin	Grin2b	IEP		Rat	PMID:20067577\|RGD:13210586
Biological Process	GO:0071363	cellular response to growth factor stimulus	Grin2b	IEP		Rat	PMID:19958814\|RGD:2325933
Biological Process	GO:0071396	cellular response to lipid	Grin2b	IEP		Rat	PMID:19819306\|RGD:2325951
Biological Process	GO:0010350	cellular response to magnesium starvation	Grin2b	IEP		Rat	PMID:17428633\|RGD:4106247
Biological Process	GO:0071287	cellular response to manganese ion	Grin2b	IEP		Rat	PMID:19643132\|RGD:2325970
Biological Process	GO:0071407	cellular response to organic cyclic compound	Grin2b	IEP		Rat	PMID:20526740\|RGD:2325861
Biological Process	GO:0021987	cerebral cortex development	Grin2b	IEP		Rat	PMID:19409459\|RGD:2325985
Biological Process	GO:0007268	chemical synaptic transmission	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:8789948
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	Grin2b	IMP		Mouse	PMID:16190898
Biological Process	GO:0009790	embryo development	Grin2b	IMP	MGI:MGI:1928293	Mouse	PMID:9458051
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:10634899
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IMP		Mouse	PMID:16157280
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:9147327
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IMP		Mouse	PMID:11530236
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IGI	MGI:MGI:95819	Mouse	PMID:14645471
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IMP		Mouse	PMID:12832518
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2b	IMP		Mouse	PMID:16045501
Biological Process	GO:0042596	fear response	Grin2b	IMP		Mouse	PMID:16157280
Biological Process	GO:0021766	hippocampus development	Grin2b	IEP		Rat	PMID:19535712\|RGD:2325978
Biological Process	GO:0001701	in utero embryonic development	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:9147327
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Grin2b	IMP		Rat	PMID:20168047\|RGD:2325881
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Grin2b	IDA		Rat	PMID:16477151\|RGD:1642190
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Grin2b	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:0007612	learning	Grin2b	IDA		Mouse	PMID:10485705
Biological Process	GO:0007612	learning	Grin2b	IMP	MGI:MGI:3701351	Mouse	PMID:16710293
Biological Process	GO:0007611	learning or memory	Grin2b	IMP		Rat	PMID:24607229\|RGD:13461747
Biological Process	GO:0007616	long-term memory	Grin2b	IEP		Rat	PMID:20581725\|RGD:4106516
Biological Process	GO:0060291	long-term synaptic potentiation	Grin2b	IGI	MGI:MGI:95820	Mouse	PMID:20661302
Biological Process	GO:0060291	long-term synaptic potentiation	Grin2b	IMP		Mouse	PMID:16901514
Biological Process	GO:0007613	memory	Grin2b	IDA		Mouse	PMID:10485705
Biological Process	GO:0007613	memory	Grin2b	IMP		Mouse	PMID:24336715
Biological Process	GO:0007613	memory	Grin2b	IMP		Mouse	PMID:16157280
Biological Process	GO:0007613	memory	Grin2b	IDA		Rat	PMID:16157280\|RGD:8553269
Biological Process	GO:0006812	monoatomic cation transport	Grin2b	IGI	MGI:MGI:95819	Mouse	PMID:7531804
Biological Process	GO:0033555	multicellular organismal response to stress	Grin2b	IEP		Rat	PMID:20309729\|RGD:2325868
Biological Process	GO:1902951	negative regulation of dendritic spine maintenance	Grin2b	IGI	UniProtKB:P04925,UniProtKB:P39688	Mouse	MGI:MGI:5447900\|PMID:22820466
Biological Process	GO:0098989	NMDA selective glutamate receptor signaling pathway	Grin2b	IMP		Rat	PMID:15987933\|RGD:12050132
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	Grin2b	IGI	UniProtKB:P35439	Rat	PMID:17526495\|RGD:13506268
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Grin2b	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:0014049	positive regulation of glutamate secretion	Grin2b	IDA		Rat	PMID:16407536\|RGD:8553534
Biological Process	GO:1901216	positive regulation of neuron death	Grin2b	IGI	UniProtKB:P04925,UniProtKB:P39688	Mouse	MGI:MGI:5447900\|PMID:22820466
Biological Process	GO:0050806	positive regulation of synaptic transmission	Grin2b	IMP		Rat	PMID:19208366\|RGD:2326032
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	Grin2b	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:0051290	protein heterotetramerization	Grin2b	IDA		Rat	PMID:24876489\|RGD:13432263
Biological Process	GO:0043113	receptor clustering	Grin2b	IDA		Rat	PMID:20008487\|RGD:4107026
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Grin2b	IMP		Rat	PMID:16904707\|RGD:1642207
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Grin2b	IMP		Rat	PMID:17655746\|RGD:1642204
Biological Process	GO:0043408	regulation of MAPK cascade	Grin2b	IMP		Rat	PMID:14622581\|RGD:8554730
Biological Process	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	Grin2b	IMP		Rat	PMID:15987933\|RGD:12050132
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Grin2b	IMP		Mouse	PMID:16157280
Biological Process	GO:0010738	regulation of protein kinase A signaling	Grin2b	IMP		Mouse	PMID:24336715
Biological Process	GO:0048167	regulation of synaptic plasticity	Grin2b	IMP		Mouse	PMID:11719203
Biological Process	GO:0048167	regulation of synaptic plasticity	Grin2b	IMP	MGI:MGI:3701351	Mouse	PMID:16710293
Biological Process	GO:0014075	response to amine	Grin2b	IEP		Rat	PMID:19918184\|RGD:2325941
Biological Process	GO:0001975	response to amphetamine	Grin2b	IEP		Rat	PMID:20422365\|RGD:4107018
Biological Process	GO:0051592	response to calcium ion	Grin2b	IEP		Rat	PMID:19761817\|RGD:2325954
Biological Process	GO:0009743	response to carbohydrate	Grin2b	IEP		Rat	PMID:19695778\|RGD:2325956
Biological Process	GO:0042220	response to cocaine	Grin2b	IEP		Rat	PMID:19322657\|RGD:2326006
Biological Process	GO:0034097	response to cytokine	Grin2b	IEP		Rat	PMID:20005040\|RGD:4107028
Biological Process	GO:0051602	response to electrical stimulus	Grin2b	IEP		Rat	PMID:20514696\|RGD:4107017
Biological Process	GO:0045471	response to ethanol	GRIN2B	IDA		Human	PMID:18445116
Biological Process	GO:0045471	response to ethanol	Grin2b	IMP		Mouse	PMID:11530236
Biological Process	GO:0045471	response to ethanol	Grin2b	IEP		Rat	PMID:19673743\|RGD:2325958
Biological Process	GO:0060992	response to fungicide	Grin2b	IEP		Rat	PMID:19591855\|RGD:2325972
Biological Process	GO:0060416	response to growth hormone	Grin2b	IEP		Rat	PMID:20237303\|RGD:4107020
Biological Process	GO:0001666	response to hypoxia	Grin2b	IDA		Rat	PMID:17270176\|RGD:13432036
Biological Process	GO:0032026	response to magnesium ion	Grin2b	IEP		Rat	PMID:20152124\|RGD:4107022
Biological Process	GO:0010042	response to manganese ion	Grin2b	IEP		Rat	PMID:20175136\|RGD:2325871
Biological Process	GO:0009612	response to mechanical stimulus	Grin2b	IEP		Rat	PMID:19778590\|RGD:2325952
Biological Process	GO:0051597	response to methylmercury	Grin2b	IEP		Rat	PMID:19409459\|RGD:2325985
Biological Process	GO:0014070	response to organic cyclic compound	Grin2b	IEP		Rat	PMID:19322657\|RGD:2326006
Biological Process	GO:0010243	response to organonitrogen compound	Grin2b	IMP		Rat	PMID:16919272\|RGD:13210770
Biological Process	GO:0051707	response to other organism	Grin2b	IEP		Rat	PMID:19563853\|RGD:2325976
Biological Process	GO:0009636	response to toxic substance	Grin2b	IEP		Rat	PMID:19954077\|RGD:4107029
Biological Process	GO:0048511	rhythmic process	Grin2b	IDA		Rat	PMID:16477151\|RGD:1642190
Biological Process	GO:0046960	sensitization	Grin2b	IMP		Rat	PMID:19167822\|RGD:13210764
Biological Process	GO:0007423	sensory organ development	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:8789948
Biological Process	GO:0001964	startle response	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:11488959
Biological Process	GO:0001964	startle response	Grin2b	IGI	MGI:MGI:95820	Mouse	PMID:16221859
Biological Process	GO:0001967	suckling behavior	Grin2b	IMP	MGI:MGI:1928295	Mouse	PMID:8789948

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.