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Gene Ontology Browser
Term Detail
GO term:late endosome
Synonym: prevacuolar compartment
Synonym: PVC
GO id:GO:0005770
Definition:A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aendomembrane system
                                        part-ofendosome
                                                is-aearly endosome +
                                                is-aendolysosome +
                                                part-ofendosomal part +
                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                        part-oflate endosome lumen +
                                                        part-oflate endosome membrane +
                                                        part-ofMon1-Ccz1 complex
                                                        is-amultivesicular body +
                                                is-apinosome +
                                                is-arecycling endosome +
                                                is-asorting endosome
                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasm
                                                        part-ofcytoplasmic part
                                                                is-aendosome
                                                                        is-aearly endosome +
                                                                        is-aendolysosome +
                                                                        part-ofendosomal part +
                                                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                                part-oflate endosome lumen +
                                                                                part-oflate endosome membrane +
                                                                                part-ofMon1-Ccz1 complex
                                                                                is-amultivesicular body +
                                                                        is-apinosome +
                                                                        is-arecycling endosome +
                                                                        is-asorting endosome
                                                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-acytoplasmic part
                                                        is-aendosome
                                                                is-aearly endosome +
                                                                is-aendolysosome +
                                                                part-ofendosomal part +
                                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                        part-oflate endosome lumen +
                                                                        part-oflate endosome membrane +
                                                                        part-ofMon1-Ccz1 complex
                                                                        is-amultivesicular body +
                                                                is-apinosome +
                                                                is-arecycling endosome +
                                                                is-asorting endosome
                                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular membrane-bounded organelle
                                                                is-aendosome
                                                                        is-aearly endosome +
                                                                        is-aendolysosome +
                                                                        part-ofendosomal part +
                                                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                                part-oflate endosome lumen +
                                                                                part-oflate endosome membrane +
                                                                                part-ofMon1-Ccz1 complex
                                                                                is-amultivesicular body +
                                                                        is-apinosome +
                                                                        is-arecycling endosome +
                                                                        is-asorting endosome
                                                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-aendosome
                                                                is-aearly endosome +
                                                                is-aendolysosome +
                                                                part-ofendosomal part +
                                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                        part-oflate endosome lumen +
                                                                        part-oflate endosome membrane +
                                                                        part-ofMon1-Ccz1 complex
                                                                        is-amultivesicular body +
                                                                is-apinosome +
                                                                is-arecycling endosome +
                                                                is-asorting endosome
                                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-acytoplasmic part
                                                is-aendosome
                                                        is-aearly endosome +
                                                        is-aendolysosome +
                                                        part-ofendosomal part +
                                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                part-oflate endosome lumen +
                                                                part-oflate endosome membrane +
                                                                part-ofMon1-Ccz1 complex
                                                                is-amultivesicular body +
                                                        is-apinosome +
                                                        is-arecycling endosome +
                                                        is-asorting endosome
                                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-aendosome
                                                                is-aearly endosome +
                                                                is-aendolysosome +
                                                                part-ofendosomal part +
                                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                        part-oflate endosome lumen +
                                                                        part-oflate endosome membrane +
                                                                        part-ofMon1-Ccz1 complex
                                                                        is-amultivesicular body +
                                                                is-apinosome +
                                                                is-arecycling endosome +
                                                                is-asorting endosome
                                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aendomembrane system
                                part-ofendosome
                                        is-aearly endosome +
                                        is-aendolysosome +
                                        part-ofendosomal part +
                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                part-oflate endosome lumen +
                                                part-oflate endosome membrane +
                                                part-ofMon1-Ccz1 complex
                                                is-amultivesicular body +
                                        is-apinosome +
                                        is-arecycling endosome +
                                        is-asorting endosome
                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasm
                                                part-ofcytoplasmic part
                                                        is-aendosome
                                                                is-aearly endosome +
                                                                is-aendolysosome +
                                                                part-ofendosomal part +
                                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                        part-oflate endosome lumen +
                                                                        part-oflate endosome membrane +
                                                                        part-ofMon1-Ccz1 complex
                                                                        is-amultivesicular body +
                                                                is-apinosome +
                                                                is-arecycling endosome +
                                                                is-asorting endosome
                                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-acytoplasmic part
                                                is-aendosome
                                                        is-aearly endosome +
                                                        is-aendolysosome +
                                                        part-ofendosomal part +
                                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                part-oflate endosome lumen +
                                                                part-oflate endosome membrane +
                                                                part-ofMon1-Ccz1 complex
                                                                is-amultivesicular body +
                                                        is-apinosome +
                                                        is-arecycling endosome +
                                                        is-asorting endosome
                                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-aendosome
                                                                is-aearly endosome +
                                                                is-aendolysosome +
                                                                part-ofendosomal part +
                                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                        part-oflate endosome lumen +
                                                                        part-oflate endosome membrane +
                                                                        part-ofMon1-Ccz1 complex
                                                                        is-amultivesicular body +
                                                                is-apinosome +
                                                                is-arecycling endosome +
                                                                is-asorting endosome
                                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasm
                                        part-ofcytoplasmic part
                                                is-aendosome
                                                        is-aearly endosome +
                                                        is-aendolysosome +
                                                        part-ofendosomal part +
                                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                part-oflate endosome lumen +
                                                                part-oflate endosome membrane +
                                                                part-ofMon1-Ccz1 complex
                                                                is-amultivesicular body +
                                                        is-apinosome +
                                                        is-arecycling endosome +
                                                        is-asorting endosome
                                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-acytoplasmic part
                                        is-aendosome
                                                is-aearly endosome +
                                                is-aendolysosome +
                                                part-ofendosomal part +
                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                        part-oflate endosome lumen +
                                                        part-oflate endosome membrane +
                                                        part-ofMon1-Ccz1 complex
                                                        is-amultivesicular body +
                                                is-apinosome +
                                                is-arecycling endosome +
                                                is-asorting endosome
                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular membrane-bounded organelle
                                                is-aendosome
                                                        is-aearly endosome +
                                                        is-aendolysosome +
                                                        part-ofendosomal part +
                                                        is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                                part-oflate endosome lumen +
                                                                part-oflate endosome membrane +
                                                                part-ofMon1-Ccz1 complex
                                                                is-amultivesicular body +
                                                        is-apinosome +
                                                        is-arecycling endosome +
                                                        is-asorting endosome
                                                        part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular membrane-bounded organelle
                                        is-aendosome
                                                is-aearly endosome +
                                                is-aendolysosome +
                                                part-ofendosomal part +
                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                        part-oflate endosome lumen +
                                                        part-oflate endosome membrane +
                                                        part-ofMon1-Ccz1 complex
                                                        is-amultivesicular body +
                                                is-apinosome +
                                                is-arecycling endosome +
                                                is-asorting endosome
                                                part-ofTRAPPII protein complex


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-amembrane-bounded organelle
                                is-aintracellular membrane-bounded organelle
                                        is-aendosome
                                                is-aearly endosome +
                                                is-aendolysosome +
                                                part-ofendosomal part +
                                                is-alate endosome [GO:0005770] (148 genes, 180 annotations)
                                                        part-oflate endosome lumen +
                                                        part-oflate endosome membrane +
                                                        part-ofMon1-Ccz1 complex
                                                        is-amultivesicular body +
                                                is-apinosome +
                                                is-arecycling endosome +
                                                is-asorting endosome
                                                part-ofTRAPPII protein complex


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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory