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Gene Ontology Browser
Term Detail
GO term:action potential
GO id:GO:0001508
Definition:A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
CommentsAction potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aaction potential [GO:0001508] (223 genes, 329 annotations)
                                                is-acardiac muscle cell action potential +
                                                part-ofmembrane depolarization during action potential +
                                                part-ofmembrane repolarization during action potential +
                                                negatively-regulatesnegative regulation of action potential +
                                                is-aneuronal action potential +
                                                positively-regulatespositive regulation of action potential +
                                                regulatesregulation of action potential +
                                        is-amembrane depolarization +
                                        is-amembrane hyperpolarization +
                                        is-amembrane repolarization +
                                        is-anegative regulation of membrane potential +
                                        is-apositive regulation of membrane potential +
                                        is-aregulation of cardiac muscle cell membrane potential
                                        is-aregulation of membrane potential in photoreceptor cell +
                                        is-aregulation of membrane repolarization +
                                        is-aregulation of mitochondrial membrane potential +
                                        is-aregulation of postsynaptic membrane potential +
                                        is-aregulation of resting membrane potential
                                        is-astabilization of membrane potential


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory