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Gene Ontology Browser
Term Detail
GO term:action potential
GO id:GO:0001508
Definition:A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
CommentsAction potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aaction potential [GO:0001508] (136 genes, 268 annotations)
                                                is-aaction potential initiation
                                                is-aaction potential propagation +
                                                is-acardiac muscle cell action potential +
                                                part-ofmembrane depolarization during action potential +
                                                part-ofmembrane repolarization during action potential +
                                                negatively-regulatesnegative regulation of action potential +
                                                is-aneuronal action potential +
                                                positively-regulatespositive regulation of action potential +
                                                regulatesregulation of action potential +
                                                is-aregulation of skeletal muscle contraction by action potential +
                                        is-amembrane depolarization +
                                        is-amembrane hyperpolarization +
                                        is-amembrane repolarization +
                                        is-amodulation of excitatory postsynaptic potential +
                                        is-amodulation of inhibitory postsynaptic potential +
                                        is-anegative regulation of membrane potential +
                                        is-apositive regulation of membrane potential +
                                        is-aregulation of action potential +
                                        is-aregulation of cardiac muscle cell membrane potential
                                        is-aregulation of membrane depolarization +
                                        is-aregulation of membrane hyperpolarization +
                                        is-aregulation of membrane potential in photoreceptor cell +
                                        is-aregulation of membrane repolarization +
                                        is-aregulation of mitochondrial membrane potential +
                                        is-aregulation of postsynaptic membrane potential +
                                        is-aregulation of presynaptic membrane potential
                                        is-aregulation of resting membrane potential
                                        is-aregulation of voltage-gated sodium channel activity +
                                        is-aspike train +
                                        is-astabilization of membrane potential

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
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