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Gene Ontology Browser
Term Detail
GO term:regulation of postsynaptic membrane potential
Synonym: regulation of post-synaptic membrane potential
GO id:GO:0060078
Definition:Any process that modulates the establishment or extent of the postsynaptic membrane potential, which is generated by changes in the membrane potential of the post synaptic neuron that receives information at a synapse. The presynaptic neuron releases neurotransmitters into the synaptic cleft which bind to receptors on the postsynaptic neuron. After being bound by the neurotransmitters, these receptors can open or close an ion channel, allowing ions to enter or leave the cell and therefore altering the membrane potential of the postsynaptic neuron.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aaction potential +
                                        is-amembrane depolarization +
                                        is-amembrane hyperpolarization +
                                        is-amembrane repolarization +
                                        is-anegative regulation of membrane potential +
                                        is-apositive regulation of membrane potential +
                                        is-aregulation of cardiac muscle cell membrane potential
                                        is-aregulation of membrane potential in photoreceptor cell +
                                        is-aregulation of membrane repolarization +
                                        is-aregulation of mitochondrial membrane potential +
                                        is-aregulation of postsynaptic membrane potential [GO:0060078] (57 genes, 85 annotations)
                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                is-aregulation of inhibitory postsynaptic membrane potential +
                                        is-aregulation of resting membrane potential
                                        is-astabilization of membrane potential


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        negatively-regulatesnegative regulation of synaptic transmission +
                                                        is-aneuromuscular synaptic transmission +
                                                        is-aneuron-neuron synaptic transmission +
                                                        part-ofneurotransmitter receptor metabolic process +
                                                        part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                        is-apositive regulation of synapse maturation by synaptic transmission
                                                        positively-regulatespositive regulation of synaptic transmission +
                                                        part-ofregulation of neurotransmitter levels +
                                                        part-ofregulation of postsynaptic membrane potential [GO:0060078] (57 genes, 85 annotations)
                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                is-aregulation of inhibitory postsynaptic membrane potential +
                                                        part-ofregulation of synapse structure and activity +
                                                        regulatesregulation of synaptic transmission +
                                                        is-asynaptic transmission, cholinergic +
                                                        part-ofsynaptic vesicle transport +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                negatively-regulatesnegative regulation of synaptic transmission +
                                                is-aneuromuscular synaptic transmission +
                                                is-aneuron-neuron synaptic transmission +
                                                part-ofneurotransmitter receptor metabolic process +
                                                part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                is-apositive regulation of synapse maturation by synaptic transmission
                                                positively-regulatespositive regulation of synaptic transmission +
                                                part-ofregulation of neurotransmitter levels +
                                                part-ofregulation of postsynaptic membrane potential [GO:0060078] (57 genes, 85 annotations)
                                                        is-aregulation of excitatory postsynaptic membrane potential +
                                                        is-aregulation of inhibitory postsynaptic membrane potential +
                                                part-ofregulation of synapse structure and activity +
                                                regulatesregulation of synaptic transmission +
                                                is-asynaptic transmission, cholinergic +
                                                part-ofsynaptic vesicle transport +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asynaptic transmission
                                negatively-regulatesnegative regulation of synaptic transmission +
                                is-aneuromuscular synaptic transmission +
                                is-aneuron-neuron synaptic transmission +
                                part-ofneurotransmitter receptor metabolic process +
                                part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                is-apositive regulation of synapse maturation by synaptic transmission
                                positively-regulatespositive regulation of synaptic transmission +
                                part-ofregulation of neurotransmitter levels +
                                part-ofregulation of postsynaptic membrane potential [GO:0060078] (57 genes, 85 annotations)
                                        is-aregulation of excitatory postsynaptic membrane potential +
                                        is-aregulation of inhibitory postsynaptic membrane potential +
                                part-ofregulation of synapse structure and activity +
                                regulatesregulation of synaptic transmission +
                                is-asynaptic transmission, cholinergic +
                                part-ofsynaptic vesicle transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                negatively-regulatesnegative regulation of synaptic transmission +
                                                is-aneuromuscular synaptic transmission +
                                                is-aneuron-neuron synaptic transmission +
                                                part-ofneurotransmitter receptor metabolic process +
                                                part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                is-apositive regulation of synapse maturation by synaptic transmission
                                                positively-regulatespositive regulation of synaptic transmission +
                                                part-ofregulation of neurotransmitter levels +
                                                part-ofregulation of postsynaptic membrane potential [GO:0060078] (57 genes, 85 annotations)
                                                        is-aregulation of excitatory postsynaptic membrane potential +
                                                        is-aregulation of inhibitory postsynaptic membrane potential +
                                                part-ofregulation of synapse structure and activity +
                                                regulatesregulation of synaptic transmission +
                                                is-asynaptic transmission, cholinergic +
                                                part-ofsynaptic vesicle transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        negatively-regulatesnegative regulation of synaptic transmission +
                                                        is-aneuromuscular synaptic transmission +
                                                        is-aneuron-neuron synaptic transmission +
                                                        part-ofneurotransmitter receptor metabolic process +
                                                        part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                        is-apositive regulation of synapse maturation by synaptic transmission
                                                        positively-regulatespositive regulation of synaptic transmission +
                                                        part-ofregulation of neurotransmitter levels +
                                                        part-ofregulation of postsynaptic membrane potential [GO:0060078] (57 genes, 85 annotations)
                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                is-aregulation of inhibitory postsynaptic membrane potential +
                                                        part-ofregulation of synapse structure and activity +
                                                        regulatesregulation of synaptic transmission +
                                                        is-asynaptic transmission, cholinergic +
                                                        part-ofsynaptic vesicle transport +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory