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Gene Ontology Browser
Term Detail
GO term:regulation of synaptic plasticity
GO id:GO:0048167
Definition:A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
CommentsNote that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
Number of paths to term: 15

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell communication
                                                is-aregulation of synaptic transmission
                                                        is-amodulation by symbiont of host synaptic transmission +
                                                        is-anegative regulation of synaptic transmission +
                                                        is-apositive regulation of synaptic transmission +
                                                        is-aregulation of acetylcholine metabolic process +
                                                        is-aregulation of neuromuscular synaptic transmission +
                                                        is-aregulation of neurotransmitter secretion +
                                                        is-aregulation of neurotransmitter uptake +
                                                        is-aregulation of synaptic activity
                                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity +
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                        is-aregulation of synaptic transmission, cholinergic +
                                                        is-aregulation of synaptic transmission, dopaminergic +
                                                        is-aregulation of synaptic transmission, GABAergic +
                                                        is-aregulation of synaptic transmission, glutamatergic +
                                                        is-aregulation of synaptic transmission, glycinergic +
                                                        is-aregulation of synaptic vesicle transport +
                                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of signaling
                                        is-aregulation of synaptic transmission
                                                is-amodulation by symbiont of host synaptic transmission +
                                                is-anegative regulation of synaptic transmission +
                                                is-apositive regulation of synaptic transmission +
                                                is-aregulation of acetylcholine metabolic process +
                                                is-aregulation of neuromuscular synaptic transmission +
                                                is-aregulation of neurotransmitter secretion +
                                                is-aregulation of neurotransmitter uptake +
                                                is-aregulation of synaptic activity
                                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                        is-along term synaptic depression +
                                                        is-along-term synaptic potentiation +
                                                        is-anegative regulation of synaptic plasticity +
                                                        is-apositive regulation of synaptic plasticity +
                                                        is-aregulation of neuronal synaptic plasticity +
                                                        is-aregulation of synaptic metaplasticity +
                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                is-aregulation of synaptic transmission, cholinergic +
                                                is-aregulation of synaptic transmission, dopaminergic +
                                                is-aregulation of synaptic transmission, GABAergic +
                                                is-aregulation of synaptic transmission, glutamatergic +
                                                is-aregulation of synaptic transmission, glycinergic +
                                                is-aregulation of synaptic vesicle transport +
                                                is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process +
                                is-amaintenance of location +
                                is-amodification of morphology or physiology of other organism +
                                is-aregulation of aggregate size involved in sorocarp development +
                                is-aregulation of anatomical structure size +
                                is-aregulation of appetite +
                                is-aregulation of blood pressure +
                                is-aregulation of body fluid levels +
                                is-aregulation of brood size
                                is-aregulation of buoyancy
                                is-aregulation of cell shape +
                                is-aregulation of cilium beat frequency involved in ciliary motility
                                is-aregulation of circulating fibrinogen levels +
                                is-aregulation of female receptivity +
                                is-aregulation of heart rate +
                                is-aregulation of hormone levels +
                                is-aregulation of membrane lipid distribution +
                                is-aregulation of membrane permeability +
                                is-aregulation of membrane potential +
                                is-aregulation of muscle filament sliding speed +
                                is-aregulation of myofibril number
                                is-aregulation of neurotransmitter levels +
                                is-aregulation of nuclear envelope permeability +
                                is-aregulation of nucleosome density
                                is-aregulation of protein complex stability
                                is-aregulation of protein stability +
                                is-aregulation of R8 cell spacing in compound eye +
                                is-aregulation of RNA stability +
                                is-aregulation of spindle density
                                is-aregulation of synapse structure and activity +
                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                        is-along term synaptic depression +
                                        is-along-term synaptic potentiation +
                                        is-anegative regulation of synaptic plasticity +
                                        is-apositive regulation of synaptic plasticity +
                                        is-aregulation of neuronal synaptic plasticity +
                                        is-aregulation of synaptic metaplasticity +
                                        is-aregulation of synaptic plasticity by chemical substance +
                                is-aregulation of the force of heart contraction +
                                is-aregulation of the velocity of shortening of skeletal muscle modulating contraction +
                                is-aregulation of translational fidelity +
                                is-aregulation of tube architecture, open tracheal system +
                                is-aregulation of tube diameter +
                                is-aregulation of tube length, open tracheal system
                                is-aregulation of vascular permeability +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of synaptic transmission
                                is-amodulation by symbiont of host synaptic transmission +
                                is-anegative regulation of synaptic transmission +
                                is-apositive regulation of synaptic transmission +
                                is-aregulation of acetylcholine metabolic process +
                                is-aregulation of neuromuscular synaptic transmission +
                                is-aregulation of neurotransmitter secretion +
                                is-aregulation of neurotransmitter uptake +
                                is-aregulation of synaptic activity
                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                        is-along term synaptic depression +
                                        is-along-term synaptic potentiation +
                                        is-anegative regulation of synaptic plasticity +
                                        is-apositive regulation of synaptic plasticity +
                                        is-aregulation of neuronal synaptic plasticity +
                                        is-aregulation of synaptic metaplasticity +
                                        is-aregulation of synaptic plasticity by chemical substance +
                                is-aregulation of synaptic transmission, cholinergic +
                                is-aregulation of synaptic transmission, dopaminergic +
                                is-aregulation of synaptic transmission, GABAergic +
                                is-aregulation of synaptic transmission, glutamatergic +
                                is-aregulation of synaptic transmission, glycinergic +
                                is-aregulation of synaptic vesicle transport +
                                is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of synaptic transmission
                                                is-amodulation by symbiont of host synaptic transmission +
                                                is-anegative regulation of synaptic transmission +
                                                is-apositive regulation of synaptic transmission +
                                                is-aregulation of acetylcholine metabolic process +
                                                is-aregulation of neuromuscular synaptic transmission +
                                                is-aregulation of neurotransmitter secretion +
                                                is-aregulation of neurotransmitter uptake +
                                                is-aregulation of synaptic activity
                                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                        is-along term synaptic depression +
                                                        is-along-term synaptic potentiation +
                                                        is-anegative regulation of synaptic plasticity +
                                                        is-apositive regulation of synaptic plasticity +
                                                        is-aregulation of neuronal synaptic plasticity +
                                                        is-aregulation of synaptic metaplasticity +
                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                is-aregulation of synaptic transmission, cholinergic +
                                                is-aregulation of synaptic transmission, dopaminergic +
                                                is-aregulation of synaptic transmission, GABAergic +
                                                is-aregulation of synaptic transmission, glutamatergic +
                                                is-aregulation of synaptic transmission, glycinergic +
                                                is-aregulation of synaptic vesicle transport +
                                                is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        regulatesregulation of synaptic transmission
                                                                is-amodulation by symbiont of host synaptic transmission +
                                                                is-anegative regulation of synaptic transmission +
                                                                is-apositive regulation of synaptic transmission +
                                                                is-aregulation of acetylcholine metabolic process +
                                                                is-aregulation of neuromuscular synaptic transmission +
                                                                is-aregulation of neurotransmitter secretion +
                                                                is-aregulation of neurotransmitter uptake +
                                                                is-aregulation of synaptic activity
                                                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                        is-along term synaptic depression +
                                                                        is-along-term synaptic potentiation +
                                                                        is-anegative regulation of synaptic plasticity +
                                                                        is-apositive regulation of synaptic plasticity +
                                                                        is-aregulation of neuronal synaptic plasticity +
                                                                        is-aregulation of synaptic metaplasticity +
                                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                                is-aregulation of synaptic transmission, cholinergic +
                                                                is-aregulation of synaptic transmission, dopaminergic +
                                                                is-aregulation of synaptic transmission, GABAergic +
                                                                is-aregulation of synaptic transmission, glutamatergic +
                                                                is-aregulation of synaptic transmission, glycinergic +
                                                                is-aregulation of synaptic vesicle transport +
                                                                is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-aregulation of synaptic transmission
                                                        is-amodulation by symbiont of host synaptic transmission +
                                                        is-anegative regulation of synaptic transmission +
                                                        is-apositive regulation of synaptic transmission +
                                                        is-aregulation of acetylcholine metabolic process +
                                                        is-aregulation of neuromuscular synaptic transmission +
                                                        is-aregulation of neurotransmitter secretion +
                                                        is-aregulation of neurotransmitter uptake +
                                                        is-aregulation of synaptic activity
                                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity +
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                        is-aregulation of synaptic transmission, cholinergic +
                                                        is-aregulation of synaptic transmission, dopaminergic +
                                                        is-aregulation of synaptic transmission, GABAergic +
                                                        is-aregulation of synaptic transmission, glutamatergic +
                                                        is-aregulation of synaptic transmission, glycinergic +
                                                        is-aregulation of synaptic vesicle transport +
                                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell communication
                                        is-aregulation of synaptic transmission
                                                is-amodulation by symbiont of host synaptic transmission +
                                                is-anegative regulation of synaptic transmission +
                                                is-apositive regulation of synaptic transmission +
                                                is-aregulation of acetylcholine metabolic process +
                                                is-aregulation of neuromuscular synaptic transmission +
                                                is-aregulation of neurotransmitter secretion +
                                                is-aregulation of neurotransmitter uptake +
                                                is-aregulation of synaptic activity
                                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                        is-along term synaptic depression +
                                                        is-along-term synaptic potentiation +
                                                        is-anegative regulation of synaptic plasticity +
                                                        is-apositive regulation of synaptic plasticity +
                                                        is-aregulation of neuronal synaptic plasticity +
                                                        is-aregulation of synaptic metaplasticity +
                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                is-aregulation of synaptic transmission, cholinergic +
                                                is-aregulation of synaptic transmission, dopaminergic +
                                                is-aregulation of synaptic transmission, GABAergic +
                                                is-aregulation of synaptic transmission, glutamatergic +
                                                is-aregulation of synaptic transmission, glycinergic +
                                                is-aregulation of synaptic vesicle transport +
                                                is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of signaling
                                is-aregulation of synaptic transmission
                                        is-amodulation by symbiont of host synaptic transmission +
                                        is-anegative regulation of synaptic transmission +
                                        is-apositive regulation of synaptic transmission +
                                        is-aregulation of acetylcholine metabolic process +
                                        is-aregulation of neuromuscular synaptic transmission +
                                        is-aregulation of neurotransmitter secretion +
                                        is-aregulation of neurotransmitter uptake +
                                        is-aregulation of synaptic activity
                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity +
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                        is-aregulation of synaptic transmission, cholinergic +
                                        is-aregulation of synaptic transmission, dopaminergic +
                                        is-aregulation of synaptic transmission, GABAergic +
                                        is-aregulation of synaptic transmission, glutamatergic +
                                        is-aregulation of synaptic transmission, glycinergic +
                                        is-aregulation of synaptic vesicle transport +
                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        regulatesregulation of signaling
                                is-aregulation of synaptic transmission
                                        is-amodulation by symbiont of host synaptic transmission +
                                        is-anegative regulation of synaptic transmission +
                                        is-apositive regulation of synaptic transmission +
                                        is-aregulation of acetylcholine metabolic process +
                                        is-aregulation of neuromuscular synaptic transmission +
                                        is-aregulation of neurotransmitter secretion +
                                        is-aregulation of neurotransmitter uptake +
                                        is-aregulation of synaptic activity
                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity +
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                        is-aregulation of synaptic transmission, cholinergic +
                                        is-aregulation of synaptic transmission, dopaminergic +
                                        is-aregulation of synaptic transmission, GABAergic +
                                        is-aregulation of synaptic transmission, glutamatergic +
                                        is-aregulation of synaptic transmission, glycinergic +
                                        is-aregulation of synaptic vesicle transport +
                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                regulatesregulation of synaptic transmission
                                                        is-amodulation by symbiont of host synaptic transmission +
                                                        is-anegative regulation of synaptic transmission +
                                                        is-apositive regulation of synaptic transmission +
                                                        is-aregulation of acetylcholine metabolic process +
                                                        is-aregulation of neuromuscular synaptic transmission +
                                                        is-aregulation of neurotransmitter secretion +
                                                        is-aregulation of neurotransmitter uptake +
                                                        is-aregulation of synaptic activity
                                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity +
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                        is-aregulation of synaptic transmission, cholinergic +
                                                        is-aregulation of synaptic transmission, dopaminergic +
                                                        is-aregulation of synaptic transmission, GABAergic +
                                                        is-aregulation of synaptic transmission, glutamatergic +
                                                        is-aregulation of synaptic transmission, glycinergic +
                                                        is-aregulation of synaptic vesicle transport +
                                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asynaptic transmission
                                regulatesregulation of synaptic transmission
                                        is-amodulation by symbiont of host synaptic transmission +
                                        is-anegative regulation of synaptic transmission +
                                        is-apositive regulation of synaptic transmission +
                                        is-aregulation of acetylcholine metabolic process +
                                        is-aregulation of neuromuscular synaptic transmission +
                                        is-aregulation of neurotransmitter secretion +
                                        is-aregulation of neurotransmitter uptake +
                                        is-aregulation of synaptic activity
                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                is-along term synaptic depression +
                                                is-along-term synaptic potentiation +
                                                is-anegative regulation of synaptic plasticity +
                                                is-apositive regulation of synaptic plasticity +
                                                is-aregulation of neuronal synaptic plasticity +
                                                is-aregulation of synaptic metaplasticity +
                                                is-aregulation of synaptic plasticity by chemical substance +
                                        is-aregulation of synaptic transmission, cholinergic +
                                        is-aregulation of synaptic transmission, dopaminergic +
                                        is-aregulation of synaptic transmission, GABAergic +
                                        is-aregulation of synaptic transmission, glutamatergic +
                                        is-aregulation of synaptic transmission, glycinergic +
                                        is-aregulation of synaptic vesicle transport +
                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                regulatesregulation of synaptic transmission
                                                        is-amodulation by symbiont of host synaptic transmission +
                                                        is-anegative regulation of synaptic transmission +
                                                        is-apositive regulation of synaptic transmission +
                                                        is-aregulation of acetylcholine metabolic process +
                                                        is-aregulation of neuromuscular synaptic transmission +
                                                        is-aregulation of neurotransmitter secretion +
                                                        is-aregulation of neurotransmitter uptake +
                                                        is-aregulation of synaptic activity
                                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity +
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                        is-aregulation of synaptic transmission, cholinergic +
                                                        is-aregulation of synaptic transmission, dopaminergic +
                                                        is-aregulation of synaptic transmission, GABAergic +
                                                        is-aregulation of synaptic transmission, glutamatergic +
                                                        is-aregulation of synaptic transmission, glycinergic +
                                                        is-aregulation of synaptic vesicle transport +
                                                        is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        regulatesregulation of synaptic transmission
                                                                is-amodulation by symbiont of host synaptic transmission +
                                                                is-anegative regulation of synaptic transmission +
                                                                is-apositive regulation of synaptic transmission +
                                                                is-aregulation of acetylcholine metabolic process +
                                                                is-aregulation of neuromuscular synaptic transmission +
                                                                is-aregulation of neurotransmitter secretion +
                                                                is-aregulation of neurotransmitter uptake +
                                                                is-aregulation of synaptic activity
                                                                is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                        is-along term synaptic depression +
                                                                        is-along-term synaptic potentiation +
                                                                        is-anegative regulation of synaptic plasticity +
                                                                        is-apositive regulation of synaptic plasticity +
                                                                        is-aregulation of neuronal synaptic plasticity +
                                                                        is-aregulation of synaptic metaplasticity +
                                                                        is-aregulation of synaptic plasticity by chemical substance +
                                                                is-aregulation of synaptic transmission, cholinergic +
                                                                is-aregulation of synaptic transmission, dopaminergic +
                                                                is-aregulation of synaptic transmission, GABAergic +
                                                                is-aregulation of synaptic transmission, glutamatergic +
                                                                is-aregulation of synaptic transmission, glycinergic +
                                                                is-aregulation of synaptic vesicle transport +
                                                                is-arhythmic synaptic transmission +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        regulatesregulation of cell communication
                                                is-aregulation of synaptic transmission
                                                        is-amodulation by symbiont of host synaptic transmission +
                                                        is-anegative regulation of synaptic transmission +
                                                        is-apositive regulation of synaptic transmission +
                                                        is-aregulation of acetylcholine metabolic process +
                                                        is-aregulation of neuromuscular synaptic transmission +
                                                        is-aregulation of neurotransmitter secretion +
                                                        is-aregulation of neurotransmitter uptake +
                                                        is-aregulation of synaptic activity
                                                        is-aregulation of synaptic plasticity [GO:0048167] (130 genes, 182 annotations)
                                                                is-along term synaptic depression +
                                                                is-along-term synaptic potentiation +
                                                                is-anegative regulation of synaptic plasticity +
                                                                is-apositive regulation of synaptic plasticity +
                                                                is-aregulation of neuronal synaptic plasticity +
                                                                is-aregulation of synaptic metaplasticity +
                                                                is-aregulation of synaptic plasticity by chemical substance +
                                                        is-aregulation of synaptic transmission, cholinergic +
                                                        is-aregulation of synaptic transmission, dopaminergic +
                                                        is-aregulation of synaptic transmission, GABAergic +
                                                        is-aregulation of synaptic transmission, glutamatergic +
                                                        is-aregulation of synaptic transmission, glycinergic +
                                                        is-aregulation of synaptic vesicle transport +
                                                        is-arhythmic synaptic transmission +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory