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Gene Ontology Browser
Term Detail
GO term:multicellular organismal response to stress
GO id:GO:0033555
Definition:Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-aadult behavior +
                                is-aage-dependent behavioral decline
                                is-abeta-amyloid clearance +
                                is-abud dormancy process
                                is-acallus formation
                                part-ofcell recognition +
                                is-acircadian regulation of gene expression
                                is-acircadian regulation of heart rate +
                                is-acircadian regulation of translation
                                is-acoagulation +
                                is-acytokine production +
                                is-adetermination of adult lifespan +
                                is-adigestion +
                                is-ahatching behavior
                                is-ainnervation +
                                is-akeratinization +
                                is-alarval behavior +
                                is-amegagametogenesis +
                                is-ameristem determinacy +
                                is-ameristem maintenance +
                                is-amicrogametogenesis +
                                is-amidbrain-hindbrain boundary maturation during brain development
                                is-amidbrain-hindbrain boundary maturation during neural plate development
                                is-amolting cycle +
                                is-amolting cycle process +
                                is-amorphogenesis of a branching structure +
                                is-amulticellular organism adhesion +
                                is-amulticellular organism growth +
                                is-amulticellular organismal development +
                                is-amulticellular organismal homeostasis +
                                is-amulticellular organismal metabolic process +
                                is-amulticellular organismal movement +
                                is-amulticellular organismal response to stress [GO:0033555] (76 genes, 97 annotations)
                                        is-afear response +
                                        is-ageneral adaptation syndrome +
                                        is-aresponse to pain +
                                is-amulticellular organismal signaling +
                                is-amuscle attachment +
                                negatively-regulatesnegative regulation of multicellular organismal process +
                                is-aneurotrophin production +
                                is-aorgan growth +
                                is-aorganism emergence from protective structure +
                                is-aossification +
                                is-aotolith tethering
                                is-apattern specification process +
                                is-aphotoreceptor cell maintenance
                                is-apigment accumulation in tissues +
                                is-aplasma lipoprotein particle clearance +
                                is-aplasma lipoprotein particle organization +
                                is-apollen germination
                                is-apolyphenic determination +
                                positively-regulatespositive regulation of multicellular organismal process +
                                is-apost-embryonic development +
                                is-aprimary growth
                                is-aproduction of molecular mediator involved in inflammatory response +
                                is-apseudocleavage +
                                is-apupariation
                                is-apupation
                                is-aregulation of body fluid levels +
                                is-arespiratory gaseous exchange +
                                is-aresponse to dietary excess +
                                is-ascab formation
                                is-asecretion by tissue +
                                is-aseed dormancy process +
                                is-aseed germination +
                                is-asleep +
                                is-astem cell maintenance +
                                is-asystem process +
                                is-atissue migration +
                                is-atissue remodeling +
                                is-atransforming growth factor beta activation +
                                is-avascular transport +
                                is-avibrational conductance of sound to the inner ear
                                is-avisual behavior +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress +
                                is-adefense response +
                                is-amulticellular organismal response to stress [GO:0033555] (76 genes, 97 annotations)
                                        is-afear response +
                                        is-ageneral adaptation syndrome +
                                        is-aresponse to pain +
                                is-amuscle hypertrophy in response to stress +
                                is-aphage shock
                                regulatesregulation of response to stress +
                                is-aresponse to anoxia +
                                is-aresponse to cold +
                                is-aresponse to flooding
                                is-aresponse to fluid shear stress +
                                is-aresponse to heat +
                                is-aresponse to herbicide
                                is-aresponse to hydrostatic pressure +
                                is-aresponse to hyperoxia +
                                is-aresponse to hypoxia +
                                is-aresponse to immobilization stress +
                                is-aresponse to ischemia
                                is-aresponse to isolation stress +
                                is-aresponse to nitrosative stress +
                                is-aresponse to osmotic stress +
                                is-aresponse to oxidative stress +
                                is-aresponse to starvation +
                                is-aresponse to sterol depletion +
                                is-aresponse to topologically incorrect protein +
                                is-aresponse to water deprivation +
                                is-aresponse to wounding +
                                is-astress response to acid chemical +
                                is-astress response to metal ion +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-aadult behavior +
                                is-aage-dependent behavioral decline
                                is-abeta-amyloid clearance +
                                is-abud dormancy process
                                is-acallus formation
                                part-ofcell recognition +
                                is-acircadian regulation of gene expression
                                is-acircadian regulation of heart rate +
                                is-acircadian regulation of translation
                                is-acoagulation +
                                is-acytokine production +
                                is-adetermination of adult lifespan +
                                is-adigestion +
                                is-ahatching behavior
                                is-ainnervation +
                                is-akeratinization +
                                is-alarval behavior +
                                is-amegagametogenesis +
                                is-ameristem determinacy +
                                is-ameristem maintenance +
                                is-amicrogametogenesis +
                                is-amidbrain-hindbrain boundary maturation during brain development
                                is-amidbrain-hindbrain boundary maturation during neural plate development
                                is-amolting cycle +
                                is-amolting cycle process +
                                is-amorphogenesis of a branching structure +
                                is-amulticellular organism adhesion +
                                is-amulticellular organism growth +
                                is-amulticellular organismal development +
                                is-amulticellular organismal homeostasis +
                                is-amulticellular organismal metabolic process +
                                is-amulticellular organismal movement +
                                is-amulticellular organismal response to stress [GO:0033555] (76 genes, 97 annotations)
                                        is-afear response +
                                        is-ageneral adaptation syndrome +
                                        is-aresponse to pain +
                                is-amulticellular organismal signaling +
                                is-amuscle attachment +
                                negatively-regulatesnegative regulation of multicellular organismal process +
                                is-aneurotrophin production +
                                is-aorgan growth +
                                is-aorganism emergence from protective structure +
                                is-aossification +
                                is-aotolith tethering
                                is-apattern specification process +
                                is-aphotoreceptor cell maintenance
                                is-apigment accumulation in tissues +
                                is-aplasma lipoprotein particle clearance +
                                is-aplasma lipoprotein particle organization +
                                is-apollen germination
                                is-apolyphenic determination +
                                positively-regulatespositive regulation of multicellular organismal process +
                                is-apost-embryonic development +
                                is-aprimary growth
                                is-aproduction of molecular mediator involved in inflammatory response +
                                is-apseudocleavage +
                                is-apupariation
                                is-apupation
                                is-aregulation of body fluid levels +
                                is-arespiratory gaseous exchange +
                                is-aresponse to dietary excess +
                                is-ascab formation
                                is-asecretion by tissue +
                                is-aseed dormancy process +
                                is-aseed germination +
                                is-asleep +
                                is-astem cell maintenance +
                                is-asystem process +
                                is-atissue migration +
                                is-atissue remodeling +
                                is-atransforming growth factor beta activation +
                                is-avascular transport +
                                is-avibrational conductance of sound to the inner ear
                                is-avisual behavior +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory