| GO term: | N-methyl-D-aspartate selective glutamate receptor activity |
| Synonym: | NMDA receptor |
| GO id: | GO:0004972 |
| Definition: | An ionotropic glutamate receptor activity that exhibits slow gating by glutamate, acts by opening a nonselective cation channel, and can be activated by L-aspartate. |
| Comments | Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'. |
| Number of paths to term: | 11 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activitytransmembrane signaling receptor activityglutamate receptor activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functionreceptor activitysignaling receptor activitytransmembrane signaling receptor activityglutamate receptor activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityionotropic glutamate receptor activityalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activity [GO:0004972] (6 genes, 22 annotations)Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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