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Gene Ontology Browser
Term Detail
GO term:synaptic transmission
Synonym: neurotransmission
Synonym: regulation of synapse
Synonym: signal transmission across a synapse
GO id:GO:0007268
Definition:The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-aautocrine signaling
                                                is-acell-cell signaling involved in amphid sensory organ development
                                                is-acell-cell signaling involved in cardiac conduction +
                                                is-acell-cell signaling involved in cell fate commitment +
                                                is-acell-cell signaling involved in cell-cell junction organization
                                                is-acell-cell signaling involved in kidney development +
                                                is-acell-cell signaling involved in lung development +
                                                is-acell-cell signaling involved in mammary gland development
                                                is-acell-cell signaling involved in placenta development
                                                is-acell-cell signaling involved in quorum sensing
                                                is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                                is-adetermination of muscle attachment site
                                                is-aectoderm and mesoderm interaction
                                                is-aendocrine signaling
                                                is-aendodermal-mesodermal cell signaling +
                                                is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                                is-aepithelial-mesenchymal cell signaling +
                                                is-amesenchymal-epithelial cell signaling +
                                                is-amesodermal-endodermal cell signaling +
                                                is-aparacrine signaling
                                                is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                                is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                                is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                                part-ofsignal release +
                                                is-astromal-epithelial cell signaling involved in prostate gland development
                                                is-asynaptic transmission [GO:0007268] (571 genes, 1084 annotations)
                                                        negatively-regulatesnegative regulation of synaptic transmission +
                                                        is-aneuromuscular synaptic transmission +
                                                        is-aneuron-neuron synaptic transmission +
                                                        part-ofneurotransmitter receptor metabolic process +
                                                        part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                        is-apositive regulation of synapse maturation by synaptic transmission
                                                        positively-regulatespositive regulation of synaptic transmission +
                                                        part-ofregulation of neurotransmitter levels +
                                                        part-ofregulation of postsynaptic membrane potential +
                                                        part-ofregulation of synapse structure and activity +
                                                        regulatesregulation of synaptic transmission +
                                                        is-asynaptic transmission, cholinergic +
                                                        part-ofsynaptic vesicle transport +
                                                is-avisceral mesoderm-endoderm interaction involved in midgut development


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-aautocrine signaling
                                        is-acell-cell signaling involved in amphid sensory organ development
                                        is-acell-cell signaling involved in cardiac conduction +
                                        is-acell-cell signaling involved in cell fate commitment +
                                        is-acell-cell signaling involved in cell-cell junction organization
                                        is-acell-cell signaling involved in kidney development +
                                        is-acell-cell signaling involved in lung development +
                                        is-acell-cell signaling involved in mammary gland development
                                        is-acell-cell signaling involved in placenta development
                                        is-acell-cell signaling involved in quorum sensing
                                        is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                        is-adetermination of muscle attachment site
                                        is-aectoderm and mesoderm interaction
                                        is-aendocrine signaling
                                        is-aendodermal-mesodermal cell signaling +
                                        is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                        is-aepithelial-mesenchymal cell signaling +
                                        is-amesenchymal-epithelial cell signaling +
                                        is-amesodermal-endodermal cell signaling +
                                        is-aparacrine signaling
                                        is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                        is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                        is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                        part-ofsignal release +
                                        is-astromal-epithelial cell signaling involved in prostate gland development
                                        is-asynaptic transmission [GO:0007268] (571 genes, 1084 annotations)
                                                negatively-regulatesnegative regulation of synaptic transmission +
                                                is-aneuromuscular synaptic transmission +
                                                is-aneuron-neuron synaptic transmission +
                                                part-ofneurotransmitter receptor metabolic process +
                                                part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                is-apositive regulation of synapse maturation by synaptic transmission
                                                positively-regulatespositive regulation of synaptic transmission +
                                                part-ofregulation of neurotransmitter levels +
                                                part-ofregulation of postsynaptic membrane potential +
                                                part-ofregulation of synapse structure and activity +
                                                regulatesregulation of synaptic transmission +
                                                is-asynaptic transmission, cholinergic +
                                                part-ofsynaptic vesicle transport +
                                        is-avisceral mesoderm-endoderm interaction involved in midgut development


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-amulti-organism signaling
                        regulatesregulation of signaling +
                        is-asingle organism signaling +
                        is-asynaptic transmission [GO:0007268] (571 genes, 1084 annotations)
                                negatively-regulatesnegative regulation of synaptic transmission +
                                is-aneuromuscular synaptic transmission +
                                is-aneuron-neuron synaptic transmission +
                                part-ofneurotransmitter receptor metabolic process +
                                part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                is-apositive regulation of synapse maturation by synaptic transmission
                                positively-regulatespositive regulation of synaptic transmission +
                                part-ofregulation of neurotransmitter levels +
                                part-ofregulation of postsynaptic membrane potential +
                                part-ofregulation of synapse structure and activity +
                                regulatesregulation of synaptic transmission +
                                is-asynaptic transmission, cholinergic +
                                part-ofsynaptic vesicle transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-aautocrine signaling
                                        is-acell-cell signaling involved in amphid sensory organ development
                                        is-acell-cell signaling involved in cardiac conduction +
                                        is-acell-cell signaling involved in cell fate commitment +
                                        is-acell-cell signaling involved in cell-cell junction organization
                                        is-acell-cell signaling involved in kidney development +
                                        is-acell-cell signaling involved in lung development +
                                        is-acell-cell signaling involved in mammary gland development
                                        is-acell-cell signaling involved in placenta development
                                        is-acell-cell signaling involved in quorum sensing
                                        is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                        is-adetermination of muscle attachment site
                                        is-aectoderm and mesoderm interaction
                                        is-aendocrine signaling
                                        is-aendodermal-mesodermal cell signaling +
                                        is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                        is-aepithelial-mesenchymal cell signaling +
                                        is-amesenchymal-epithelial cell signaling +
                                        is-amesodermal-endodermal cell signaling +
                                        is-aparacrine signaling
                                        is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                        is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                        is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                        part-ofsignal release +
                                        is-astromal-epithelial cell signaling involved in prostate gland development
                                        is-asynaptic transmission [GO:0007268] (571 genes, 1084 annotations)
                                                negatively-regulatesnegative regulation of synaptic transmission +
                                                is-aneuromuscular synaptic transmission +
                                                is-aneuron-neuron synaptic transmission +
                                                part-ofneurotransmitter receptor metabolic process +
                                                part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                is-apositive regulation of synapse maturation by synaptic transmission
                                                positively-regulatespositive regulation of synaptic transmission +
                                                part-ofregulation of neurotransmitter levels +
                                                part-ofregulation of postsynaptic membrane potential +
                                                part-ofregulation of synapse structure and activity +
                                                regulatesregulation of synaptic transmission +
                                                is-asynaptic transmission, cholinergic +
                                                part-ofsynaptic vesicle transport +
                                        is-avisceral mesoderm-endoderm interaction involved in midgut development


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-aautocrine signaling
                                                is-acell-cell signaling involved in amphid sensory organ development
                                                is-acell-cell signaling involved in cardiac conduction +
                                                is-acell-cell signaling involved in cell fate commitment +
                                                is-acell-cell signaling involved in cell-cell junction organization
                                                is-acell-cell signaling involved in kidney development +
                                                is-acell-cell signaling involved in lung development +
                                                is-acell-cell signaling involved in mammary gland development
                                                is-acell-cell signaling involved in placenta development
                                                is-acell-cell signaling involved in quorum sensing
                                                is-acerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation +
                                                is-adetermination of muscle attachment site
                                                is-aectoderm and mesoderm interaction
                                                is-aendocrine signaling
                                                is-aendodermal-mesodermal cell signaling +
                                                is-aepiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
                                                is-aepithelial-mesenchymal cell signaling +
                                                is-amesenchymal-epithelial cell signaling +
                                                is-amesodermal-endodermal cell signaling +
                                                is-aparacrine signaling
                                                is-aregulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling
                                                is-aregulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
                                                is-aregulation of pre-tubular aggregate formation by cell-cell signaling
                                                part-ofsignal release +
                                                is-astromal-epithelial cell signaling involved in prostate gland development
                                                is-asynaptic transmission [GO:0007268] (571 genes, 1084 annotations)
                                                        negatively-regulatesnegative regulation of synaptic transmission +
                                                        is-aneuromuscular synaptic transmission +
                                                        is-aneuron-neuron synaptic transmission +
                                                        part-ofneurotransmitter receptor metabolic process +
                                                        part-ofphenylethylamine metabolic process involved in synaptic transmission +
                                                        is-apositive regulation of synapse maturation by synaptic transmission
                                                        positively-regulatespositive regulation of synaptic transmission +
                                                        part-ofregulation of neurotransmitter levels +
                                                        part-ofregulation of postsynaptic membrane potential +
                                                        part-ofregulation of synapse structure and activity +
                                                        regulatesregulation of synaptic transmission +
                                                        is-asynaptic transmission, cholinergic +
                                                        part-ofsynaptic vesicle transport +
                                                is-avisceral mesoderm-endoderm interaction involved in midgut development


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory