| GO term: | lysosome |
| GO id: | GO:0005764 |
| Definition: | A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. |
| Number of paths to term: | 14 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partintracellularintracellular partcytoplasmcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcellcell partintracellularintracellular partcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular membrane-bounded organellevacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcellcell partintracellular partcytoplasmcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcellcell partintracellular partcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcellcell partintracellular partintracellular organelleintracellular membrane-bounded organellevacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcell partintracellularintracellular partcytoplasmcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcell partintracellularintracellular partcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcell partintracellularintracellular partintracellular organelleintracellular membrane-bounded organellevacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcell partintracellular partcytoplasmcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcell partintracellular partcytoplasmic partvacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentcell partintracellular partintracellular organelleintracellular membrane-bounded organellevacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentorganelleintracellular organelleintracellular membrane-bounded organellevacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuolecellular_componentorganellemembrane-bounded organelleintracellular membrane-bounded organellevacuolelytic vacuolefungal-type vacuole +lysosome [GO:0005764] (287 genes, 361 annotations)cytolytic granuleendolysosome +lysosomal glycocalyxlysosomal lumen +lysosomal membrane +lysosomal multienzyme complexmast cell granulemegasomeprimary lysosome +secondary lysosome +UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complexlytic vacuole within protein storage vacuolesenescence-associated vacuoleMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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