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Gene Ontology Browser
Term Detail
GO term:postsynaptic density
Synonym: post synaptic density
Synonym: post-synaptic density
GO id:GO:0014069
Definition:The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at an excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include structural proteins linked to the actin cytoskeleton and signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.
Number of paths to term: 14

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular non-membrane-bounded organelle
                                                                is-apostsynaptic specialization
                                                                        is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                                                is-aglial cell postsynaptic density
                                                                                is-amuscle cell postsynaptic density
                                                                                is-aneuronal postsynaptic density +
                                                                        is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-apostsynaptic specialization
                                                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                                        is-aglial cell postsynaptic density
                                                                        is-amuscle cell postsynaptic density
                                                                        is-aneuronal postsynaptic density +
                                                                is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-apostsynapse
                                        part-ofpostsynaptic specialization
                                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                        is-aglial cell postsynaptic density
                                                        is-amuscle cell postsynaptic density
                                                        is-aneuronal postsynaptic density +
                                                is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-apostsynaptic specialization
                                                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                                        is-aglial cell postsynaptic density
                                                                        is-amuscle cell postsynaptic density
                                                                        is-aneuronal postsynaptic density +
                                                                is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular non-membrane-bounded organelle
                                                is-apostsynaptic specialization
                                                        is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                                is-aglial cell postsynaptic density
                                                                is-amuscle cell postsynaptic density
                                                                is-aneuronal postsynaptic density +
                                                        is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-apostsynapse
                                part-ofpostsynaptic specialization
                                        is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                is-aglial cell postsynaptic density
                                                is-amuscle cell postsynaptic density
                                                is-aneuronal postsynaptic density +
                                        is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-apostsynaptic specialization
                                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                        is-aglial cell postsynaptic density
                                                        is-amuscle cell postsynaptic density
                                                        is-aneuronal postsynaptic density +
                                                is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-anon-membrane-bounded organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-apostsynaptic specialization
                                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                        is-aglial cell postsynaptic density
                                                        is-amuscle cell postsynaptic density
                                                        is-aneuronal postsynaptic density +
                                                is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-asynapse
                        is-aexcitatory synapse
                                is-aexcitatory neuromuscular junction +
                                part-ofpostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                        is-aglial cell postsynaptic density
                                        is-amuscle cell postsynaptic density
                                        is-aneuronal postsynaptic density +


obsolete Gene_Ontology
        is-acellular_component
                is-asynapse
                        part-ofpostsynapse
                                part-ofpostsynaptic specialization
                                        is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                is-aglial cell postsynaptic density
                                                is-amuscle cell postsynaptic density
                                                is-aneuronal postsynaptic density +
                                        is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-asynapse
                        part-ofsynapse part
                                is-apostsynapse
                                        part-ofpostsynaptic specialization
                                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                        is-aglial cell postsynaptic density
                                                        is-amuscle cell postsynaptic density
                                                        is-aneuronal postsynaptic density +
                                                is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-asynapse
                        part-ofsynapse part
                                is-apostsynaptic specialization
                                        is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                is-aglial cell postsynaptic density
                                                is-amuscle cell postsynaptic density
                                                is-aneuronal postsynaptic density +
                                        is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-asynapse part
                        is-apostsynapse
                                part-ofpostsynaptic specialization
                                        is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                                is-aglial cell postsynaptic density
                                                is-amuscle cell postsynaptic density
                                                is-aneuronal postsynaptic density +
                                        is-apostsynaptic specialization of inhibitory synapse


obsolete Gene_Ontology
        is-acellular_component
                is-asynapse part
                        is-apostsynaptic specialization
                                is-apostsynaptic density [GO:0014069] (207 genes, 246 annotations)
                                        is-aglial cell postsynaptic density
                                        is-amuscle cell postsynaptic density
                                        is-aneuronal postsynaptic density +
                                is-apostsynaptic specialization of inhibitory synapse


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory