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Gene Ontology Browser
Term Detail
GO term:regulation of excitatory postsynaptic membrane potential
Synonym: regulation of EPSP
Synonym: regulation of excitatory post-synaptic membrane potential
GO id:GO:0060079
Definition:Any process that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Number of paths to term: 22

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-acellular homeostasis
                                                is-acellular chemical homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-amembrane depolarization
                                                                                is-amembrane depolarization involved in regulation of action potential +
                                                                                is-amitochondrial depolarization +
                                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                                regulatesregulation of membrane depolarization +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-acellular homeostasis
                                                is-acellular chemical homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-aregulation of postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-achemical homeostasis
                                                is-acellular chemical homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-amembrane depolarization
                                                                                is-amembrane depolarization involved in regulation of action potential +
                                                                                is-amitochondrial depolarization +
                                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                                regulatesregulation of membrane depolarization +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-achemical homeostasis
                                                is-acellular chemical homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-aregulation of postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-achemical homeostasis
                                                is-aion homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-amembrane depolarization
                                                                                is-amembrane depolarization involved in regulation of action potential +
                                                                                is-amitochondrial depolarization +
                                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                                regulatesregulation of membrane depolarization +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-achemical homeostasis
                                                is-aion homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-aregulation of postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-oftransmission of nerve impulse
                                                part-ofsynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular homeostasis
                                        is-acellular chemical homeostasis
                                                is-acellular ion homeostasis
                                                        is-aregulation of membrane potential
                                                                is-amembrane depolarization
                                                                        is-amembrane depolarization involved in regulation of action potential +
                                                                        is-amitochondrial depolarization +
                                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                        regulatesregulation of membrane depolarization +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular homeostasis
                                        is-acellular chemical homeostasis
                                                is-acellular ion homeostasis
                                                        is-aregulation of membrane potential
                                                                is-aregulation of postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofsynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-aneurological system process
                                                is-atransmission of nerve impulse
                                                        part-ofsynaptic transmission
                                                                part-ofregulation of postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofsynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofsynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofsynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-aneurological system process
                                                is-atransmission of nerve impulse
                                                        part-ofsynaptic transmission
                                                                part-ofregulation of postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-oftransmission of nerve impulse
                                                part-ofsynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular homeostasis
                                        is-acellular chemical homeostasis
                                                is-acellular ion homeostasis
                                                        is-aregulation of membrane potential
                                                                is-amembrane depolarization
                                                                        is-amembrane depolarization involved in regulation of action potential +
                                                                        is-amitochondrial depolarization +
                                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                        regulatesregulation of membrane depolarization +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular homeostasis
                                        is-acellular chemical homeostasis
                                                is-acellular ion homeostasis
                                                        is-aregulation of membrane potential
                                                                is-aregulation of postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (43 genes, 58 annotations)
                                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory