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Gene Ontology Browser
Term Detail
GO term:regulation of excitatory postsynaptic membrane potential
Synonym: regulation of EPSP
Synonym: regulation of excitatory post-synaptic membrane potential
GO id:GO:0060079
Definition:Any process that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-amembrane depolarization
                                                is-amembrane depolarization during action potential +
                                                is-amitochondrial depolarization +
                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                regulatesregulation of membrane depolarization +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aregulation of postsynaptic membrane potential
                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asynaptic transmission
                                part-ofregulation of postsynaptic membrane potential
                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-acell-cell signaling
                                        is-asynaptic transmission
                                                part-ofregulation of postsynaptic membrane potential
                                                        is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                                is-anegative regulation of excitatory postsynaptic membrane potential
                                                                is-apositive regulation of excitatory postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                        is-aregulation of inhibitory postsynaptic membrane potential +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        is-acell-cell signaling
                                                is-asynaptic transmission
                                                        part-ofregulation of postsynaptic membrane potential
                                                                is-aregulation of excitatory postsynaptic membrane potential [GO:0060079] (49 genes, 63 annotations)
                                                                        is-anegative regulation of excitatory postsynaptic membrane potential
                                                                        is-apositive regulation of excitatory postsynaptic membrane potential
                                                                        is-aregulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
                                                                is-aregulation of inhibitory postsynaptic membrane potential +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory