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Gene Ontology Browser
Term Detail
GO term:ionotropic glutamate receptor activity
GO id:GO:0004970
Definition:Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
CommentsNote that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'.
Number of paths to term: 8

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-aglutamate receptor activity
                                                        is-aadenylate cyclase inhibiting G-protein coupled glutamate receptor activity +
                                                        is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                is-akainate selective glutamate receptor activity
                                                                is-aN-methyl-D-aspartate selective glutamate receptor activity
                                                        is-aPLC activating G-protein coupled glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-aglutamate receptor activity
                                                is-aadenylate cyclase inhibiting G-protein coupled glutamate receptor activity +
                                                is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                        is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                        is-akainate selective glutamate receptor activity
                                                        is-aN-methyl-D-aspartate selective glutamate receptor activity
                                                is-aPLC activating G-protein coupled glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                                is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                                is-akainate selective glutamate receptor activity
                                                                                is-aN-methyl-D-aspartate selective glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                                is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                                is-akainate selective glutamate receptor activity
                                                                                is-aN-methyl-D-aspartate selective glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-agated channel activity
                                                        is-aligand-gated channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aextracellular ligand-gated ion channel activity
                                                                                is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                                is-aextracellular ammonia-gated ion channel activity
                                                                                is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                                is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                                is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                                        is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                                        is-akainate selective glutamate receptor activity
                                                                                        is-aN-methyl-D-aspartate selective glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-asubstrate-specific channel activity
                                                        is-aion channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aextracellular ligand-gated ion channel activity
                                                                                is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                                is-aextracellular ammonia-gated ion channel activity
                                                                                is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                                is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                                is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                                        is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                                        is-akainate selective glutamate receptor activity
                                                                                        is-aN-methyl-D-aspartate selective glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                                is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                                is-akainate selective glutamate receptor activity
                                                                                is-aN-methyl-D-aspartate selective glutamate receptor activity


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aextracellular ligand-gated ion channel activity
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity [GO:0004970] (19 genes, 67 annotations)
                                                                                is-aalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
                                                                                is-akainate selective glutamate receptor activity
                                                                                is-aN-methyl-D-aspartate selective glutamate receptor activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory