| GO term: | ionotropic glutamate receptor activity |
| GO id: | GO:0004970 |
| Definition: | Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. |
| Comments | Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'. |
| Number of paths to term: | 11 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activitytransmembrane signaling receptor activityglutamate receptor activityadenylate cyclase inhibiting G-protein coupled glutamate receptor activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activityPLC activating G-protein coupled glutamate receptor activitymolecular_functionreceptor activitysignaling receptor activitytransmembrane signaling receptor activityglutamate receptor activityadenylate cyclase inhibiting G-protein coupled glutamate receptor activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activityPLC activating G-protein coupled glutamate receptor activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activitymolecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityextracellular ligand-gated ion channel activityexcitatory extracellular ligand-gated ion channel activity +extracellular ammonia-gated ion channel activityextracellular phenylacetaldehyde-gated ion channel activityinhibitory extracellular ligand-gated ion channel activity +ionotropic glutamate receptor activity [GO:0004970] (18 genes, 59 annotations)alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activitykainate selective glutamate receptor activityN-methyl-D-aspartate selective glutamate receptor activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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