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Col1a1tm13(neo/hygro*)Jae
Targeted Allele Detail
Nomenclature
Symbol: Col1a1tm13(neo/hygro*)Jae
Name: collagen, type I, alpha 1; targeted mutation 13, Rudolf Jaenisch
MGI ID: MGI:5507043
Gene: Col1a1  Location: Chr11:94936224-94953042 bp, + strand  Genetic Position: Chr11, 59.01 cM, cytoband D
Mutation
origin
Germline Transmission:  Unknown
Parent Cell Line:  KH2 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (RMCE-ready)
Mutation:    Insertion
 
Mutation detailsES cells containing the Gt(ROSA)26Sortm1(rtTA*M2)Jae allele were subsequently targeted to insert an FRT flanked PGK-neomycin resistance gene followed by a promoterless and ATG-less hygromycin resistance gene. This allele can be used for RMCE. (J:98920)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:  134 strains or lines available
Notes
This allele was used to generate: Col1a1tm1(tetO/CMV-Lep)Rll, Col1a1tm1(tetO-CTNNB1)Tcd, Col1a1tm1(tetO-Cyp26b1)Mfra, Col1a1tm10(tetO-Dnmt3b_i3)Jae, Col1a1tm10(tetO*-RFP/RNAi:Rpa3)Slowe, Col1a1tm11(tetO-Dnmt3b_i6)Jae, Col1a1tm11(tetO*-RFP/RNAi:Rpa3)Slowe, Col1a1tm12(tetO-Dnmt3a_i1)Jae, Col1a1tm13(tetO-GFP/RNAi:Brd4)Slowe, Col1a1tm14(tetO-GFP/RNAi:Brd4)Slowe, Col1a1tm15(tetO-GFP/RNAi:Ren)Slowe, Col1a1tm16(tetO-GFP/RNAi:Trim33)Slowe, Col1a1tm17(tetO-GFP,-cas9*)Slowe, Col1a1tm18(tetO-GFP,-cas9*)Slowe, Col1a1tm19(tetO-GFP,-cas9*)Slowe, Col1a1tm1(CAG-Ezh2*)Meln, Col1a1tm1(CMV/tetO-Kdm2b)Atz, Col1a1tm1(Sry)Aqui, Col1a1tm1(tetO-ACMSD)Mmf, Col1a1tm1(tetO-cas9)Sho, Col1a1tm1(tetO-Ccnb1)Jvd, Col1a1tm1(tetO-CDKN2A)Ibp, Col1a1tm1(tetO-Cdx1)Ywng, Col1a1tm1(tetO-Deptor)Dmsa, Col1a1tm1(tetO-Fos)Wag, Col1a1tm1(tetO-Gata4/mCherry)Amza, Col1a1tm1(tetO-GFP/RNAi:luc)Slowe, Col1a1tm1(tetO-GFP/RNAi:Pax5)Radi, Col1a1tm1(tetO-GFP/RNAi:rluc)Beggs, Col1a1tm1(tetO-GFP/RNAi:Sirt1)Pyc, Col1a1tm1(tetO-GFP/RNAi:Stat3)Ern, Col1a1tm1(tetO-KMT2A/ELL)Dbry, Col1a1tm1(tetO-Lin28a)Gqda, Col1a1tm1(tetO-mCherry)Eggn, Col1a1tm1(tetO-Msi1)Cjl, Col1a1tm1(tetO-Pou5f1,-Klf4,-Sox2,-Myc)Hoch, Col1a1tm1(tetO-RNAi:Ptgs2,GFP)Hahe, Col1a1tm1(tetO-RNAi:Rps19)Karl, Col1a1tm1(tetO-SOX2)Mjm, Col1a1tm1(tetO-Stat1)Biat, Col1a1tm1(tetO-Tcfap2c)Hsc, Col1a1tm1(tetO-U2AF1*S34F)Mjwa, Col1a1tm1(tetO-URI1)Ndj, Col1a1tm1(tetO-YAP1*)Fcam, Col1a1tm1(tetO-Yap1*)Lrsn, Col1a1tm1(tetO-Yod1*)Hpl, Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe, Col1a1tm2(CMV/tetO-Kdm2b*)Atz, Col1a1tm2(Sry)Aqui, Col1a1tm2(tetO-Ccnb2)Jvd, Col1a1tm2(tetO-Fosl2,-DsRed)Wag, Col1a1tm2(tetO-GFP/RNAi:Ren)Radi, Col1a1tm2(tetO-GFP/RNAi:Rpl5)Beggs, Col1a1tm2(tetO-GFP/RNAi:Trp53)Slowe, Col1a1tm2(tetO-LIN28B)Gqda, Col1a1tm2(tetO-RNAi:Rps19)Karl, Col1a1tm2(tetO-U2AF1)Mjwa, Col1a1tm2(tetO-URI1*S371A)Ndj, Col1a1tm2(tetO-Yap1)Lrsn, Col1a1tm3(Sry)Aqui, Col1a1tm3(tet0-Ccne1)Jvd, Col1a1tm3(tetO-Fosl1,-DsRed)Wag, Col1a1tm3(tetO-GFP/RNAi:Apc)Slowe, Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda, Col1a1tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae, Col1a1tm4(Sry)Aqui, Col1a1tm4(tetO-GFP/RNAi:Apc)Slowe, Col1a1tm4(tetO-Jun/Fosl2)Wag, Col1a1tm4(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae, Col1a1tm5(Sry)Aqui, Col1a1tm5(tetO-GFP/RNAi:Cdkn2a)Slowe, Col1a1tm5(tetO-Jun/Fos)Wag, Col1a1tm5(tetO-Pou5f1,-Klf4,-Myc)Jae, Col1a1tm6(tetO-GFP/RNAi:Cdkn2a)Slowe, Col1a1tm6(tetO-Junb/Fos,-DsRed)Wag, Col1a1tm6(tetO-MSI2)Jae, Col1a1tm7(tetO-GFP/RNAi:rluc)Slowe, Col1a1tm7(tetO-HIST1H2BJ/GFP)Jae, Col1a1tm7(tetO-Jund/Fos)Wag, Col1a1tm7(tetO-Pou5f1,-Klf4,-Sox2,-mCherry)Hoch, Col1a1tm8(tetO-GFP/RNAi:Rpa3)Slowe, Col1a1tm9(tetO-Dnmt3b_i1)Jae, Col1a1tm9(tetO-GFP/RNAi:Rpa3)Slowe.
References
Original:  J:98920 Hochedlinger K, et al., Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell. 2005 May 6;121(3):465-77
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory