Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Col1a1tm1(tetO-Msi1)Cjl
Name:	collagen, type I, alpha 1; targeted mutation 1, Christopher Lengner
MGI ID:	MGI:6355982
Synonyms:	TRE-Msi1
Gene:	Col1a1  Location: Chr11:94827050-94843868 bp, + strand  Genetic Position: Chr11, 59.01 cM, cytoband D
Alliance:	Col1a1tm1(tetO-Msi1)Cjl page

Germline Transmission:	Earliest citation of germline transmission: J:273980
Parent Cell Line:	KH2 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Mutation details: RMCE on KH2 cells replaced the FRT-flanked neo cassette with a cassette that contains a splice acceptor, polyadenylation sequence and the tetracycline promoter driving inducible expression of a cDNA for mouse Msi1 followed by a polyadenylation sequence and hygromycin resistance cassette with an FRT site. (J:273980)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:	160 strains or lines available

Original:	J:273980 Li N, et al., The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins. Cell Rep. 2015 Dec 22;13(11):2440-2455
All:	1 reference(s)