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Mammalian Phenotype Ontology Annotations
Query Results - Summary
118 genotypes with 120 annotations displayed of selected term and subterms
Searched Term: abnormal cell cycle checkpoint function
Allelic Composition
(Genetic Background)		 Annotated Term Reference
Acdtm1.1Blas/Acdtm1.1Blas
Tg(KRT5-cre)1Tak/?
(involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * SJL) 		abnormal cell cycle checkpoint function J:160600
Atmtm1Awb/Atmtm1Awb
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal cell cycle checkpoint function J:103922
Atmtm1Awb/Atmtm1Awb
(involves: 129S6/SvEvTac) 		abnormal cell cycle checkpoint function J:126920
Atmtm1Awb/Atmtm1Awb
Rad50tm2Jpt/Rad50tm2Jpt
(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6) 		abnormal cell cycle checkpoint function J:103922
Atmtm1Bal/Atmtm1Bal
(involves: 129S4/SvJae) 		abnormal cell cycle checkpoint function J:42324
Atmtm1Pmc/Atmtm1Pmc
(Not Specified) 		abnormal cell cycle checkpoint function J:78491
Brca1tm2.1Cxd/Brca1tm2.1Cxd
Trp53tm1Brd/Trp53+
(involves: 129S6/SvEvTac * 129S7/SvEvBrd) 		abnormal cell cycle checkpoint function J:70271
Brca1tm2Mak/Brca1tm2Mak
Tg(Lck-cre)548Jxm/?
(involves: 129P2/OlaHsd * C57BL/6 * CBA) 		abnormal cell cycle checkpoint function J:63282
Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi
Emx1tm1(cre)Krj/Emx1+
(involves: 129S2/SvPas * C57BL/6J * C57BL/6N) 		abnormal cell cycle checkpoint function J:224155
Bub1tm1.1Jvd/Bub1+
(involves: 129/Sv * C57BL/6) 		abnormal cell cycle checkpoint function J:135093
Bub1tm1.1Jvd/Bub1tm2Jvd
(involves: 129/Sv * C57BL/6) 		abnormal cell cycle checkpoint function J:135093
Bub1tm1.1Tvd/Bub1tm1.1Tvd
(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J) 		abnormal cell cycle checkpoint function J:143035
abnormal mitotic spindle assembly checkpoint J:143035
Bub1tm1Ssta/Bub1tm1.1Ssta
Tg(CAG-cre/Esr1*)5Amc/?
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA) 		abnormal mitotic spindle assembly checkpoint J:128455
Bub1tm2Jvd/Bub1+
(involves: 129/Sv * C57BL/6) 		abnormal cell cycle checkpoint function J:135093
Bub1tm2Jvd/Bub1tm2Jvd
(involves: 129/Sv * C57BL/6) 		abnormal cell cycle checkpoint function J:135093
Bub1tm3.1Jvd/Bub1tm3.1Jvd
(involves: 129S4/SvJae * C57BL/6) 		abnormal cell cycle checkpoint function J:195237
Bub1bGt(neo-btk)1Dai/Bub1b+
(involves: 129S4/SvJae) 		abnormal mitotic spindle assembly checkpoint J:88094
Bub1btm1.1Hsl/Bub1b+
Tg(HIST1H2BB/EGFP)1Pa/0
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:201641
Bub1btm1.1Jvd/Bub1b+
(involves: 129S6/SvEvTac) 		abnormal cell cycle checkpoint function J:105717
Bub1btm1.1Jvd/Bub1b+
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:293084
Bub1btm1Jvd/Bub1b+
(involves: 129S6/SvEvTac) 		abnormal cell cycle checkpoint function J:105717
Bub1btm1Jvd/Bub1btm1Jvd
(involves: 129S6/SvEvTac) 		abnormal cell cycle checkpoint function J:105717
Bub1btm1Jvd/Bub1btm1Jvd
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:293084
Bub1btm1Jvd/Bub1btm2.1Jvd
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:293084
Bub1btm1Jvd/Bub1btm3.1Jvd
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:293084
Bub1btm2.1Jvd/Bub1b+
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:293084
Bub1btm3.1Jvd/Bub1b+
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:293084
Bub3tm1Jvd/Bub3+
(Not Specified) 		abnormal cell cycle checkpoint function J:81546, J:105717
Bub3tm1Jvd/Bub3+
Rae1tm1Jvd/Rae1+
(Not Specified) 		abnormal cell cycle checkpoint function J:105717
CacybpGT(OST39970)Lex/CacybpGT(OST39970)Lex
(involves: 129S5/SvEvBrd) 		abnormal cell cycle checkpoint function J:110899
Casz1tm1.1Flc/Casz1tm1.1Flc
Nkx2-5tm1(cre)Rjs/Nkx2-5+
(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL) 		abnormal cell cycle checkpoint function J:221324
Cdc25am1Rfp/Cdc25am1Rfp
(multiple strains) 		abnormal cell cycle checkpoint function J:80142
Cdkn1atm1Led/Cdkn1atm1Led
(involves: 129S6/SvEvTac) 		abnormal cell cycle checkpoint function J:57882
Cdx2tm1Mmt/Cdx2+
(B6.129X1-Cdx2tm1Mmt) 		abnormal cell cycle checkpoint function J:86737
Cdx2tm1Mmt/Cdx2+
Apctm1Mmt/Apc+
(B6.129-Cdx2tm1Mmt Apctm1Mmt) 		abnormal cell cycle checkpoint function J:86737
Chek1tm1Mkt/Chek1tm1Mkt
(involves: 129P2/OlaHsd * C57BL/6J) 		abnormal cell cycle checkpoint function J:62918
Chek1tm1Sje/Chek1tm1Sje
(Not Specified) 		abnormal cell cycle checkpoint function J:62919
Chek2tm1Mak/Chek2tm1Mak
(involves: 129P2/OlaHsd * C57BL/6) 		abnormal cell cycle checkpoint function J:78491
Chmp2btm1.1Hiok/Chmp2b+
(involves: C57BL/6J) 		abnormal cell cycle checkpoint function J:308471
Col1a1tm11(tetO-Nup88)Jvd/Col1a1+
(involves: 129S4/SvJae * C57BL/6) 		abnormal cell cycle checkpoint function J:231166
Col1a1tm13(tetO-Nup88)Jvd/Col1a1+
(involves: 129S4/SvJae * C57BL/6) 		abnormal cell cycle checkpoint function J:231166
Cops5tm1Rpar/Cops5tm1Rpar
Tg(Lck-cre)548Jxm/0
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL) 		abnormal cell cycle checkpoint function J:132114
Cul4atm1.1Pra/Cul4atm1.1Pra
(involves: C57BL/6NTac) 		abnormal cell cycle checkpoint function J:172043
Cul4atm1.2Pz/Cul4atm1.2Pz
(B6.Cg-Cul4atm1.2Pz) 		abnormal cell cycle checkpoint function J:150427
Del(17Hspa1b-Hsp1a)1Dix/Del(17Hspa1b-Hsp1a)1Dix
(involves: 129S7/SvEvBrd) 		abnormal cell cycle checkpoint function J:87581
Ercc6ltm1.2Ajlc/Y
(involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL/J) 		abnormal cell cycle checkpoint function J:271028
Fancctm1Mgo/Fancctm1Mgo
(involves: 129S4/SvJaeSor * C57BL/6) 		abnormal cell cycle checkpoint function J:61512
Fignfi/Fignfi
Vsx2or/Vsx2or
(involves: C57BL/Gr) 		abnormal cell cycle checkpoint function J:5575
Gabpatm1Agro/Gabpatm1Agro
(involves: 129) 		abnormal cell cycle checkpoint function J:126422
Gcn1em2Itohk/Gcn1em2Itohk
(C57BL/6-Gcn1em2Itohk) 		abnormal cell cycle checkpoint function J:287528
Grntm1.1Hiok/Grn+
(involves: C57BL/6J) 		abnormal cell cycle checkpoint function J:308471
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/0
Smc5tm1c(KOMP)Wtsi/Smc5tm1d(KOMP)Wtsi
(involves: 129S4/SvJae * C57BL/6N * CBA) 		abnormal mitotic spindle assembly checkpoint J:240155
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
Lin9tm1.1Sgau/Lin9+
(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL) 		abnormal mitotic spindle assembly checkpoint J:162678
Hmgn1tm1Mbus/Hmgn1tm1Mbus
(involves: 129X1/SvJ) 		abnormal cell cycle checkpoint function J:100773
Hus1tm1Led/Hus1tm2Rsw
(involves: 129S6/SvEvTac * C57BL/6) 		abnormal cell cycle checkpoint function J:118898
Kif18agcd2/Kif18agcd2
(CAST.129S1(B6)-Kif18agcd2/JcsMmjax) 		abnormal cell cycle checkpoint function J:222418
abnormal mitotic spindle assembly checkpoint J:222418
Kmt5atm1.1Dare/Kmt5atm1.2Dare
Tg(CAG-cre/Esr1*)5Amc/0
(involves: 129S1/Sv * C57BL/6 * CBA * SJL) 		abnormal cell cycle checkpoint function J:147765
LmnaDhe/Lmna+
(B6(D2)-LmnaDhe/TyGrsrJ) 		abnormal mitotic spindle assembly checkpoint J:171665
Mad1l1tm1.1Ktj/Mad1l1+
(involves: BALB/c * C57BL/6J) 		abnormal mitotic spindle assembly checkpoint J:117337
Mad1l1tm1.1Ktj/Mad1l1+
Mad2l1tm1Sorg/Mad2l1+
(involves: 129S2/SvPas * BALB/c * C57BL/6J) 		abnormal mitotic spindle assembly checkpoint J:117337
Mad2l1tm1Sorg/Mad2l1tm1Sorg
(involves: 129S2/SvPas * C57BL/6) 		abnormal mitotic spindle assembly checkpoint J:62829
Mafbkr/Mafbkr
(CBA.Cg-Mafbkr) 		abnormal cell cycle checkpoint function J:5392
Mbd4/Ift122tm1Abc/Mbd4/Ift122tm1Abc
(either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)) 		abnormal cell cycle checkpoint function J:86981
Mbd4/Ift122tm1Abc/Mbd4/Ift122tm1Abc
(either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)) 		abnormal cell cycle checkpoint function J:86981
Mbd4tm2Abc/Mbd4tm2Abc
(involves: 129/Sv * 129X1/SvJ * C57BL/6) 		abnormal cell cycle checkpoint function J:86981
Mdm2tm1Bay/Mdm2tm1Mep
(involves: 129S7/SvEvBrd * C57BL/6) 		abnormal cell cycle checkpoint function J:81065
Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas * 129S5/SvEvBrd) 		abnormal cell cycle checkpoint function J:77907
Mre11atm1.1Rchd/Mre11atm1.1Rchd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal cell cycle checkpoint function J:184053
Mre11atm1Jpt/Mre11atm1Jpt
(involves: 129S7/SvEvBrd * C57BL/6) 		abnormal cell cycle checkpoint function J:87088, J:103922
Mre11atm1Jpt/Mre11atm1Jpt
Rad50tm2Jpt/Rad50tm2Jpt
(involves: 129S7/SvEvBrd * C57BL/6) 		abnormal cell cycle checkpoint function J:103922
Mre11atm2.1Dof/Mre11atm2.2Dof
(Not Specified) 		abnormal cell cycle checkpoint function J:147247
Nbntm1Jpt/Nbntm1Jpt
(involves: 129S7/SvEvBrd) 		abnormal cell cycle checkpoint function J:75956
Nup98tm1Jvd/Nup98+
Rae1tm1Jvd/Rae1+
(Not Specified) 		abnormal cell cycle checkpoint function J:231166
Parp1tm1Jmdm/Parp1tm1Jmdm
(involves: 129S2/SvPas * C57BL/6) 		abnormal cell cycle checkpoint function J:41742
Parp2tm1Jmdm/Parp2tm1Jmdm
(involves: 129S2/SvPas * C57BL/6) 		abnormal cell cycle checkpoint function J:83371
Pax6tm1.1Zkoz/Pax6tm1.1Zkoz
Tg(Rax-cre)1Zkoz/0
(Not Specified) 		abnormal cell cycle checkpoint function J:208421
Plk3tm1Pjs/Plk3tm1Pjs
(involves: 129S6/SvEvTac * Black Swiss) 		abnormal cell cycle checkpoint function J:175096
Ppp5cGt(XG029)Byg/Ppp5cGt(XG029)Byg
(involves: 129P2/OlaHsd * C57BL/6J) 		abnormal cell cycle checkpoint function J:122564
Pqbp1tm1.1Hiok/Y
Tg(Nes-cre)1Kln/0
(involves: C57BL/6 * C57BL/6J) 		abnormal cell cycle checkpoint function J:279053
Psme3tm1Jjm/Psme3tm1Jjm
(B6.129X1-Psme3tm1Jjm) 		abnormal cell cycle checkpoint function J:88626
Ptpn6me/Ptpn6me
(C57BL/6J-Ptpn6me/J) 		abnormal cell cycle checkpoint function J:66843
Pttg1tm1Pzg/Pttg1tm1Pzg
(involves: 129S7/SvEvBrd * C57BL/6) 		abnormal cell cycle checkpoint function J:121688
Rae1tm1Jvd/Rae1+
(Not Specified) 		abnormal cell cycle checkpoint function J:81546, J:105717
Rasa3scat/Rasa3scat
(involves: BALB/cBy * BALB/cByJ) 		abnormal cell cycle checkpoint function J:281271
Rb1tm1Dwg/Rb1tm1Dwg
(involves: 129/Sv * C57BL/6) 		abnormal cell cycle checkpoint function J:105548
Rb1tm1Tyj/Rb1tm1Tyj
(involves: 129S2/SvPas) 		abnormal cell cycle checkpoint function J:105548
Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal cell cycle checkpoint function J:198260
Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal cell cycle checkpoint function J:198260
Setd7tm1Frga/Setd7+
(involves: 129 * C57BL/6) 		abnormal cell cycle checkpoint function J:136558
Setd7tm1Frga/Setd7tm1Frga
(involves: 129 * C57BL/6) 		abnormal cell cycle checkpoint function J:136558
Sin3btm1.2Rdp/Sin3btm1.2Rdp
(involves: 129 * C57BL/6 * FVB/N * SJL) 		abnormal cell cycle checkpoint function J:154855
Sirt1tm1.1Cxd/Sirt1tm1.1Cxd
(either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)) 		abnormal cell cycle checkpoint function J:140089
Smc1atm1Mbk/Y
(involves: 129S1/Sv * C57BL/6) 		abnormal cell cycle checkpoint function J:104490
Sptbn1tm1c(EUCOMM)Wtsi/Sptbn1tm1c(EUCOMM)Wtsi
(involves: C57BL/6J * C57BL/6N) 		abnormal cell cycle checkpoint function J:219548
Syf2Gt(PST25562)Mfgc/Syf2Gt(PST25562)Mfgc
(involves: 129P2/OlaHsd * C57BL/6) 		abnormal cell cycle checkpoint function J:187030
Tardbptm1.1Hiok/Tardbp+
(involves: C57BL/6J) 		abnormal cell cycle checkpoint function J:308471
Tg(CAG-cre/Esr1*)5Amc/0
Wee1tm1Cxd/Wee1tm1Cxd
(involves: 129S6/SvEvTac * C57BL/6 * CBA) 		abnormal cell cycle checkpoint function J:228492
Tg(KRT14-HPV16E7)2304Plam/0
(involves: FVB/N) 		abnormal cell cycle checkpoint function J:101623
Tg(Lck-Akt1*)M-1Pnt/0
(involves: C3H/He * C57BL/6) 		abnormal cell cycle checkpoint function J:73487
Tg(Lck-Akt1*E40K)E-3Pnt/0
(involves: C3H/He * C57BL/6) 		abnormal cell cycle checkpoint function J:73487
Tpx2Gt(D028B03)1.1Wrst/Tpx2Gt(D028B03)1.1Wrst
(involves: 129S2/SvPas * C57BL/6J) 		abnormal mitotic spindle assembly checkpoint J:184948
Trem2tm1(KOMP)Vlcg/Trem2tm1(KOMP)Vlcg
(C57BL/6N-Trem2tm1(KOMP)Vlcg) 		abnormal cell cycle checkpoint function J:239381
Trp53tm1Att/Trp53tm1Att
(involves: 129S4/SvJae) 		abnormal cell cycle checkpoint function J:96433
Trp53tm1Brd/Trp53tm1Brd
(involves: 129S7/SvEvBrd) 		abnormal cell cycle checkpoint function J:78491, J:126186
Trp53tm1Brd/Trp53tm1Brd
(involves: 129S7/SvEvBrd * C57BL/6) 		abnormal cell cycle checkpoint function J:126497
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas) 		abnormal cell cycle checkpoint function J:126920, J:77907
Trp53tm4Xu/Trp53tm4Xu
(Not Specified) 		abnormal cell cycle checkpoint function J:126497
Trp53tm7.1Xu/Trp53+
(Not Specified) 		abnormal cell cycle checkpoint function J:160414
Trp53tm7.1Xu/Trp53tm7.1Xu
(Not Specified) 		abnormal cell cycle checkpoint function J:160414
Trp53bp1tm1Jc/Trp53bp1tm1Jc
(involves: 129 * C57BL/6) 		abnormal cell cycle checkpoint function J:82512
Trp53bp2tm1Cdlo/Trp53bp2+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal cell cycle checkpoint function J:146764
Tspyl2tm1Sich/Y
(involves: 129S/SvEv) 		abnormal cell cycle checkpoint function J:174549
Tspyl2tm1Sich/Tspyl2tm1Sich
(involves: 129S/SvEv) 		abnormal cell cycle checkpoint function J:174549
Uimc1tm1.2Amj/Uimc1tm1.2Amj
(involves: BALB/cJ * C57BL/6) 		abnormal cell cycle checkpoint function J:191827
Vcptm1.1Hiok/Vcp+
(B6(Cg)-Vcptm1.1Hiok) 		abnormal cell cycle checkpoint function J:308471
Vsx2or/Vsx2or
(involves: C57BL/Gr) 		abnormal cell cycle checkpoint function J:5575
Wdr62Gt(AF0003)Wtsi/Wdr62Gt(AF0003)Wtsi
(involves: 129P2/OlaHsd * 129S1/SvImJ) 		abnormal mitotic spindle assembly checkpoint J:224504
Wee1tm1.1Cxd/Wee1tm1.1Cxd
(involves: 129S6/SvEvTac * FVB/N) 		abnormal cell cycle checkpoint function J:228492
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory