Cul4a^tm1.1Pra
Targeted Allele Detail

Summary

• Symbol: Cul4a^tm1.1Pra
• Name: cullin 4A; targeted mutation 1.1, Pradip Raychaudhuri
• MGI ID: MGI:5003269
• Synonyms: Cul4A fl
• Gene: Cul4a Location: Chr8:13155623-13197940 bp, + strand Genetic Position: Chr8, 5.73 cM
• Alliance: Cul4a^tm1.1Pra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172043
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 4 through 8 were floxed. A floxed neo cassette used for selection was removed by cre-mediated recombination. (J:172043)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cul4a Mutation: 30 strains or lines available

References

• Original: J:172043 Kopanja D, et al., Proliferation defects and genome instability in cells lacking Cul4A. Oncogene. 2009 Jul 2;28(26):2456-65
• All: 2 reference(s)