Pax6^tm1.1Zkoz
Targeted Allele Detail

Summary

• Symbol: Pax6^tm1.1Zkoz
• Name: paired box 6; targeted mutation 1.1, Zbynek Kozmik
• MGI ID: MGI:5567084
• Synonyms: Pax6^fl
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^tm1.1Zkoz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208421
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites flanking exons 3 and 6 were inserted into Pax6 locus by homologous recombination. (J:208421)

Expression

In Mice Carrying this Mutation:	265 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 90 strains or lines available

References

• Original: J:208421 Klimova L, et al., Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302
• All: 4 reference(s)