Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ezh2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes EZH2
- Mouse genes Ezh2
- Rat genes Ezh2
- Zfish genes ezh2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ezh2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	EZH2	IDA		Human	PMID:20154697
Molecular Function	GO:0003682	chromatin binding	Ezh2	IDA		Mouse	PMID:25547114
Molecular Function	GO:0003682	chromatin binding	Ezh2	IDA		Mouse	PMID:24105743
Molecular Function	GO:0003682	chromatin binding	Ezh2	IDA		Mouse	PMID:15520282
Molecular Function	GO:0003682	chromatin binding	Ezh2	IDA		Mouse	PMID:22056776
Molecular Function	GO:0003682	chromatin binding	Ezh2	IDA		Mouse	PMID:23046516
Molecular Function	GO:0003682	chromatin binding	Ezh2	IDA		Rat	PMID:23932971\|RGD:9587811
Molecular Function	GO:0031490	chromatin DNA binding	EZH2	IDA		Human	PMID:19734898
Molecular Function	GO:0031490	chromatin DNA binding	Ezh2	IDA		Mouse	PMID:24137001
Molecular Function	GO:0031490	chromatin DNA binding	Ezh2	IDA		Mouse	PMID:18483221
Molecular Function	GO:0003677	DNA binding	Ezh2	IDA		Mouse	PMID:23942234
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	EZH2	IDA		Human	PMID:22323599
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	EZH2	IMP		Human	PMID:28229514
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	EZH2	IMP		Human	PMID:30026490
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	Ezh2	IMP		Mouse	MGI:MGI:3694308\|PMID:16717091
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	ezh2	IMP	ZFIN:ZDB-GENO-171114-12	Zfish	PMID:28887218
Molecular Function	GO:0042054	histone methyltransferase activity	EZH2	IDA		Human	PMID:15385962
Molecular Function	GO:0042054	histone methyltransferase activity	EZH2	IMP		Human	PMID:26694085
Molecular Function	GO:0042054	histone methyltransferase activity	Ezh2	IDA		Mouse	PMID:12900441
Molecular Function	GO:0106222	lncRNA binding	Ezh2	IDA		Mouse	PMID:27618650
Molecular Function	GO:0070878	primary miRNA binding	Ezh2	IDA		Mouse	PMID:24137001
Molecular Function	GO:1990841	promoter-specific chromatin binding	EZH2	IDA		Human	PMID:24623306
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:11571280
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:P78395	Human	PMID:16179254
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:P26358	Human	PMID:16357870
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9UBC3	Human	PMID:16357870
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9Y6K1	Human	PMID:16357870
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:P10276	Human	PMID:17560333
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15156	Human	PMID:17560333
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:19734898
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:20075857
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q92833-1	Human	PMID:20075857
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9Y232	Human	PMID:22009739
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:22094255
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:P26358	Human	PMID:22094255
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9UBC3	Human	PMID:22094255
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:22439931
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:22439931
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q8IXJ9	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:23079660
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:23142980
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:23238014
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43463	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:P40763	Human	PMID:23684459
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:23684459
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9CWR8	Human	PMID:24074865
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9UBC3	Human	PMID:24074865
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9Y6K1	Human	PMID:24074865
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:24183680
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O15294	Human	PMID:24474760
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q96MT8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:P46100	Human	PMID:25417162
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:27728805
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q9UBC3	Human	PMID:27728808
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:28229514
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:28229514
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022,UniProtKB:Q86X51	Human	PMID:29909548
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q5T9G4	Human	PMID:30026490
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022,UniProtKB:Q86X51	Human	PMID:30923826
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q96MT8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O14978	Human	PMID:32051553
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O43189	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:O75530	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	EZH2	IPI	UniProtKB:Q15022	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q921E6	Mouse	MGI:MGI:5926701\|PMID:17937919
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q921E6	Mouse	MGI:MGI:5300666\|PMID:22094255
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:O08785\|UniProtKB:P97784\|UniProtKB:Q9WTL8	Mouse	MGI:MGI:3694308\|PMID:16717091
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q921E6	Mouse	MGI:MGI:5508304\|PMID:9742080
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q80U70	Mouse	MGI:MGI:5499261\|PMID:23624935
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q80U70	Mouse	MGI:MGI:5499263\|PMID:23624931
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:P38398	Mouse	MGI:MGI:5499261\|PMID:23624935
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q921E6	Mouse	MGI:MGI:4441020\|PMID:20075857
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q80U70\|UniProtKB:Q9CWR8	Mouse	MGI:MGI:5553039\|PMID:24074865
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q62315	Mouse	MGI:MGI:5286758\|PMID:21811233
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q62315\|UniProtKB:Q80U70\|UniProtKB:Q921E6	Mouse	MGI:MGI:4431292\|PMID:20064375
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q62315\|UniProtKB:Q80U70\|UniProtKB:Q921E6	Mouse	MGI:MGI:4436818\|PMID:20064376
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	UniProtKB:Q02395	Mouse	MGI:MGI:4436818\|PMID:20064376
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	PR:Q921E6	Mouse	PMID:12900441
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	PR:O09106	Mouse	PMID:12900441
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	PR:Q921E6	Mouse	PMID:9584197
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	PR:Q921E6	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	PR:Q921E6	Mouse	PMID:17997413
Molecular Function	GO:0005515	protein binding	Ezh2	IPI	PR:P59598	Mouse	PMID:24216483
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	EZH2	IDA		Human	PMID:19144645
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	Ezh2	IDA		Mouse	PMID:25547114
Molecular Function	GO:0043021	ribonucleoprotein complex binding	Ezh2	IDA		Mouse	PMID:21172659
Molecular Function	GO:0003723	RNA binding	Ezh2	IPI	MGI:MGI:4439832	Mouse	PMID:26423156
Molecular Function	GO:0003723	RNA binding	Ezh2	IDA		Mouse	PMID:21936910
Molecular Function	GO:0003723	RNA binding	Ezh2	IPI	MGI:MGI:3826586	Mouse	PMID:21123648
Molecular Function	GO:0003723	RNA binding	Ezh2	IPI	MGI:MGI:3623820	Mouse	PMID:22911650
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Ezh2	IDA		Mouse	PMID:24137001
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	Ezh2	IDA		Mouse	PMID:20798045
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	Ezh2	IMP		Mouse	PMID:16717091
Molecular Function	GO:0043565	sequence-specific DNA binding	Ezh2	IDA		Mouse	PMID:20956546
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Ezh2	IMP		Rat	PMID:22821416\|RGD:7242953
Molecular Function	GO:0003713	transcription coactivator activity	ezh2	IDA		Zfish	PMID:29447387
Molecular Function	GO:0003713	transcription coactivator activity	ezh2	IMP		Zfish	PMID:29447387
Molecular Function	GO:0003712	transcription coregulator activity	ezh2	IMP		Zfish	PMID:29447387
Molecular Function	GO:0003712	transcription coregulator activity	ezh2	IDA		Zfish	PMID:29447387
Molecular Function	GO:0003714	transcription corepressor activity	Ezh2	IDA		Mouse	MGI:MGI:3820717\|PMID:19026781
Molecular Function	GO:0001222	transcription corepressor binding	EZH2	IPI	UniProtKB:Q8N3X6	Human	PMID:29628311
Molecular Function	GO:0001222	transcription corepressor binding	EZH2	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0000785	chromatin	EZH2	IDA		Human	PMID:19734898
Cellular Component	GO:0005677	chromatin silencing complex	Ezh2	IDA		Mouse	PMID:26658965
Cellular Component	GO:0000781	chromosome, telomeric region	EZH2	IGI	UniProtKB:P38827	Human	PMID:9214638
Cellular Component	GO:0005737	cytoplasm	Ezh2	IDA		Rat	PMID:22821416\|RGD:7242953
Cellular Component	GO:0035098	ESC/E(Z) complex	EZH2	IDA		Human	PMID:15385962
Cellular Component	GO:0035098	ESC/E(Z) complex	EZH2	IDA		Human	PMID:20075857
Cellular Component	GO:0035098	ESC/E(Z) complex	EZH2	IDA		Human	PMID:23104054
Cellular Component	GO:0035098	ESC/E(Z) complex	EZH2	IDA		Human	PMID:23273982
Cellular Component	GO:0035098	ESC/E(Z) complex	EZH2	IDA		Human	PMID:24474760
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	MGI:MGI:3820717\|PMID:19026781
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	MGI:MGI:4436818\|PMID:20064376
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	MGI:MGI:4429983\|PMID:20144788
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	MGI:MGI:5487475\|PMID:23160351
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	MGI:MGI:4431292\|PMID:20064375
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	MGI:MGI:5318799\|PMID:22438827
Cellular Component	GO:0035098	ESC/E(Z) complex	Ezh2	IDA		Mouse	PMID:31451685
Cellular Component	GO:0005654	nucleoplasm	EZH2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EZH2	IDA		Human	PMID:19144645
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:22482507
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:22949634
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:19303854
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:15520282
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:9584197
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:18483221
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Mouse	PMID:23046516
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Rat	PMID:22821416\|RGD:7242953
Cellular Component	GO:0005634	nucleus	Ezh2	IDA		Rat	PMID:23932971\|RGD:9587811
Cellular Component	GO:0005721	pericentric heterochromatin	Ezh2	IDA		Mouse	PMID:27892467
Cellular Component	GO:0045120	pronucleus	Ezh2	IDA		Mouse	PMID:12900441
Biological Process	GO:0030183	B cell differentiation	Ezh2	IMP	MGI:MGI:3624790	Mouse	PMID:23531880
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	Ezh2	IDA		Mouse	PMID:24137001
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ezh2	IDA		Mouse	PMID:20808772
Biological Process	GO:0035984	cellular response to trichostatin A	Ezh2	IMP		Mouse	PMID:24137001
Biological Process	GO:0021695	cerebellar cortex development	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:20798045
Biological Process	GO:0048565	digestive tract development	ezh2	IMP	ZFIN:ZDB-GENO-171114-12	Zfish	PMID:28887218
Biological Process	GO:0048565	digestive tract development	ezh2	IMP	ZFIN:ZDB-GENO-160804-1	Zfish	PMID:27145952
Biological Process	GO:0006306	DNA methylation	Ezh2	IMP		Mouse	PMID:24105743
Biological Process	GO:0009913	epidermal cell differentiation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0140718	facultative heterochromatin formation	Ezh2	IDA		Mouse	MGI:MGI:4436818\|PMID:20064376
Biological Process	GO:0140718	facultative heterochromatin formation	Ezh2	IDA		Mouse	MGI:MGI:4431292\|PMID:20064375
Biological Process	GO:0031101	fin regeneration	ezh2	IMP	ZFIN:ZDB-GENO-171114-12	Zfish	PMID:28887218
Biological Process	GO:0070314	G1 to G0 transition	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0007507	heart development	ezh2	IMP	ZFIN:ZDB-GENO-160804-1	Zfish	PMID:27145952
Biological Process	GO:0030097	hemopoiesis	Ezh2	IMP	MGI:MGI:3624790	Mouse	PMID:23531880
Biological Process	GO:0036333	hepatocyte homeostasis	Ezh2	IGI	MGI:MGI:1097695	Mouse	PMID:25477280
Biological Process	GO:0021766	hippocampus development	Ezh2	IEP		Rat	PMID:23932971\|RGD:9587811
Biological Process	GO:0016570	histone modification	Ezh2	IMP		Rat	PMID:22821416\|RGD:7242953
Biological Process	GO:0030216	keratinocyte differentiation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0097421	liver regeneration	Ezh2	IGI	MGI:MGI:1097695	Mouse	PMID:25477280
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	Ezh2	IMP		Rat	PMID:27690696\|RGD:126781724
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Ezh2	IGI	MGI:MGI:102858	Mouse	PMID:25547114
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	EZH2	IMP		Human	PMID:16179254
Biological Process	GO:0045605	negative regulation of epidermal cell differentiation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0010629	negative regulation of gene expression	Ezh2	IMP		Rat	PMID:22821416\|RGD:7242953
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	EZH2	IDA		Human	PMID:20154697
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	EZH2	IMP		Human	PMID:24623306
Biological Process	GO:0045617	negative regulation of keratinocyte differentiation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	EZH2	IMP		Human	PMID:16179254
Biological Process	GO:2000737	negative regulation of stem cell differentiation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0051154	negative regulation of striated muscle cell differentiation	Ezh2	IDA		Mouse	PMID:15520282
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	EZH2	IDA		Human	PMID:20154697
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ezh2	IDA		Mouse	PMID:24105743
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ezh2	IMP		Rat	PMID:23932971\|RGD:9587811
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	EZH2	IMP		Human	PMID:18713946
Biological Process	GO:0008284	positive regulation of cell population proliferation	EZH2	IMP		Human	PMID:18713946
Biological Process	GO:0042753	positive regulation of circadian rhythm	ezh2	IMP		Zfish	PMID:29447387
Biological Process	GO:0042753	positive regulation of circadian rhythm	ezh2	IDA		Zfish	PMID:29447387
Biological Process	GO:1900006	positive regulation of dendrite development	Ezh2	IMP		Rat	PMID:23932971\|RGD:9587811
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	EZH2	IDA		Human	PMID:20154697
Biological Process	GO:0043547	positive regulation of GTPase activity	EZH2	IDA		Human	PMID:20154697
Biological Process	GO:1903708	positive regulation of hemopoiesis	ezh2	IMP		Zfish	PMID:29447387
Biological Process	GO:0043406	positive regulation of MAP kinase activity	EZH2	IDA		Human	PMID:20154697
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	EZH2	IDA		Human	PMID:20154697
Biological Process	GO:0071168	protein localization to chromatin	Ezh2	IMP	MGI:MGI:3805309	Mouse	PMID:18311137
Biological Process	GO:0042127	regulation of cell population proliferation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0042752	regulation of circadian rhythm	EZH2	IMP		Human	PMID:16717091
Biological Process	GO:0042752	regulation of circadian rhythm	Ezh2	IMP		Mouse	MGI:MGI:3694308\|PMID:16717091
Biological Process	GO:0010468	regulation of gene expression	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:20798045
Biological Process	GO:0010468	regulation of gene expression	Ezh2	IMP		Mouse	PMID:24137001
Biological Process	GO:0014013	regulation of gliogenesis	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:20798045
Biological Process	GO:0090183	regulation of kidney development	Ezh2	IEP		Rat	PMID:18467665\|RGD:155631277
Biological Process	GO:0050767	regulation of neurogenesis	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:20798045
Biological Process	GO:0001932	regulation of protein phosphorylation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ezh2	IMP	MGI:MGI:2661097,MGI:MGI:3574960	Mouse	PMID:21498568
Biological Process	GO:0032355	response to estradiol	Ezh2	IEP		Rat	PMID:25088689\|RGD:9588323
Biological Process	GO:1904772	response to tetrachloromethane	Ezh2	IGI	MGI:MGI:1097695	Mouse	PMID:25477280
Biological Process	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	Ezh2	IMP	MGI:MGI:2661097,MGI:MGI:3574960	Mouse	PMID:21498568
Biological Process	GO:0048863	stem cell differentiation	Ezh2	IMP	MGI:MGI:2661097	Mouse	PMID:19303854
Biological Process	GO:0031509	subtelomeric heterochromatin formation	EZH2	IGI	UniProtKB:P38827	Human	PMID:9214638
Biological Process	GO:0051932	synaptic transmission, GABAergic	Ezh2	IMP		Rat	PMID:27690696\|RGD:126781724
Biological Process	GO:0001894	tissue homeostasis	ezh2	IMP	ZFIN:ZDB-GENO-160804-1	Zfish	PMID:27145952

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.