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Gene Ontology Browser
Term Detail
GO term:epidermal cell differentiation
Synonym: hypodermal cell differentiation
GO id:GO:0009913
Definition:The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation +
                                                        is-acumulus cell differentiation +
                                                        is-aendothelial cell differentiation +
                                                        is-aepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepithelial cell development +
                                                        is-aepithelial cell differentiation involved in embryonic placenta development +
                                                        is-aepithelial cell differentiation involved in kidney development +
                                                        is-aepithelial cell differentiation involved in prostate gland development +
                                                        is-aepithelial cell differentiation involved in salivary gland development +
                                                        part-ofepithelial cell fate commitment +
                                                        is-agranulosa cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-ahepatocyte differentiation +
                                                        is-aleading edge cell differentiation +
                                                        is-alens fiber cell differentiation +
                                                        is-alung epithelial cell differentiation +
                                                        is-aMalpighian tubule principal cell differentiation
                                                        is-aMalpighian tubule stellate cell differentiation
                                                        is-amammary gland epithelial cell differentiation +
                                                        is-amulti-ciliated epithelial cell differentiation
                                                        negatively-regulatesnegative regulation of epithelial cell differentiation +
                                                        is-aodontoblast differentiation +
                                                        is-apolarized epithelial cell differentiation +
                                                        positively-regulatespositive regulation of epithelial cell differentiation +
                                                        regulatesregulation of epithelial cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        is-aSertoli cell differentiation +
                                                        is-aureter epithelial cell differentiation


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        is-askin development
                                                part-ofepidermis development
                                                        part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepidermis morphogenesis +
                                                        is-ahair follicle development +
                                                        is-alimb epidermis development +
                                                        negatively-regulatesnegative regulation of epidermis development +
                                                        is-aplant epidermis development +
                                                        positively-regulatespositive regulation of epidermis development +
                                                        regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                is-askin development
                                                        part-ofepidermis development
                                                                part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                        part-ofepidermal cell fate specification +
                                                                        is-ahair cell differentiation +
                                                                        is-akeratinocyte differentiation +
                                                                        is-alimb basal epidermal cell differentiation +
                                                                        negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                        positively-regulatespositive regulation of epidermal cell differentiation +
                                                                        regulatesregulation of epidermal cell differentiation +
                                                                        is-asebaceous gland cell differentiation
                                                                part-ofepidermis morphogenesis +
                                                                is-ahair follicle development +
                                                                is-alimb epidermis development +
                                                                negatively-regulatesnegative regulation of epidermis development +
                                                                is-aplant epidermis development +
                                                                positively-regulatespositive regulation of epidermis development +
                                                                regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-aepidermis development
                                                part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                        part-ofepidermal cell fate specification +
                                                        is-ahair cell differentiation +
                                                        is-akeratinocyte differentiation +
                                                        is-alimb basal epidermal cell differentiation +
                                                        negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                        positively-regulatespositive regulation of epidermal cell differentiation +
                                                        regulatesregulation of epidermal cell differentiation +
                                                        is-asebaceous gland cell differentiation
                                                part-ofepidermis morphogenesis +
                                                is-ahair follicle development +
                                                is-alimb epidermis development +
                                                negatively-regulatesnegative regulation of epidermis development +
                                                is-aplant epidermis development +
                                                positively-regulatespositive regulation of epidermis development +
                                                regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-aepithelium development
                                                is-aepidermis development
                                                        part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepidermis morphogenesis +
                                                        is-ahair follicle development +
                                                        is-alimb epidermis development +
                                                        negatively-regulatesnegative regulation of epidermis development +
                                                        is-aplant epidermis development +
                                                        positively-regulatespositive regulation of epidermis development +
                                                        regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-aepithelium development
                                                part-ofepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation +
                                                        is-acumulus cell differentiation +
                                                        is-aendothelial cell differentiation +
                                                        is-aepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepithelial cell development +
                                                        is-aepithelial cell differentiation involved in embryonic placenta development +
                                                        is-aepithelial cell differentiation involved in kidney development +
                                                        is-aepithelial cell differentiation involved in prostate gland development +
                                                        is-aepithelial cell differentiation involved in salivary gland development +
                                                        part-ofepithelial cell fate commitment +
                                                        is-agranulosa cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-ahepatocyte differentiation +
                                                        is-aleading edge cell differentiation +
                                                        is-alens fiber cell differentiation +
                                                        is-alung epithelial cell differentiation +
                                                        is-aMalpighian tubule principal cell differentiation
                                                        is-aMalpighian tubule stellate cell differentiation
                                                        is-amammary gland epithelial cell differentiation +
                                                        is-amulti-ciliated epithelial cell differentiation
                                                        negatively-regulatesnegative regulation of epithelial cell differentiation +
                                                        is-aodontoblast differentiation +
                                                        is-apolarized epithelial cell differentiation +
                                                        positively-regulatespositive regulation of epithelial cell differentiation +
                                                        regulatesregulation of epithelial cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        is-aSertoli cell differentiation +
                                                        is-aureter epithelial cell differentiation


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation +
                                                        is-acumulus cell differentiation +
                                                        is-aendothelial cell differentiation +
                                                        is-aepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepithelial cell development +
                                                        is-aepithelial cell differentiation involved in embryonic placenta development +
                                                        is-aepithelial cell differentiation involved in kidney development +
                                                        is-aepithelial cell differentiation involved in prostate gland development +
                                                        is-aepithelial cell differentiation involved in salivary gland development +
                                                        part-ofepithelial cell fate commitment +
                                                        is-agranulosa cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-ahepatocyte differentiation +
                                                        is-aleading edge cell differentiation +
                                                        is-alens fiber cell differentiation +
                                                        is-alung epithelial cell differentiation +
                                                        is-aMalpighian tubule principal cell differentiation
                                                        is-aMalpighian tubule stellate cell differentiation
                                                        is-amammary gland epithelial cell differentiation +
                                                        is-amulti-ciliated epithelial cell differentiation
                                                        negatively-regulatesnegative regulation of epithelial cell differentiation +
                                                        is-aodontoblast differentiation +
                                                        is-apolarized epithelial cell differentiation +
                                                        positively-regulatespositive regulation of epithelial cell differentiation +
                                                        regulatesregulation of epithelial cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        is-aSertoli cell differentiation +
                                                        is-aureter epithelial cell differentiation


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-askin development
                                                                part-ofepidermis development
                                                                        part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                                part-ofepidermal cell fate specification +
                                                                                is-ahair cell differentiation +
                                                                                is-akeratinocyte differentiation +
                                                                                is-alimb basal epidermal cell differentiation +
                                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                                regulatesregulation of epidermal cell differentiation +
                                                                                is-asebaceous gland cell differentiation
                                                                        part-ofepidermis morphogenesis +
                                                                        is-ahair follicle development +
                                                                        is-alimb epidermis development +
                                                                        negatively-regulatesnegative regulation of epidermis development +
                                                                        is-aplant epidermis development +
                                                                        positively-regulatespositive regulation of epidermis development +
                                                                        regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-askin development
                                                                part-ofepidermis development
                                                                        part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                                part-ofepidermal cell fate specification +
                                                                                is-ahair cell differentiation +
                                                                                is-akeratinocyte differentiation +
                                                                                is-alimb basal epidermal cell differentiation +
                                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                                regulatesregulation of epidermal cell differentiation +
                                                                                is-asebaceous gland cell differentiation
                                                                        part-ofepidermis morphogenesis +
                                                                        is-ahair follicle development +
                                                                        is-alimb epidermis development +
                                                                        negatively-regulatesnegative regulation of epidermis development +
                                                                        is-aplant epidermis development +
                                                                        positively-regulatespositive regulation of epidermis development +
                                                                        regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-askin development
                                                                part-ofepidermis development
                                                                        part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                                part-ofepidermal cell fate specification +
                                                                                is-ahair cell differentiation +
                                                                                is-akeratinocyte differentiation +
                                                                                is-alimb basal epidermal cell differentiation +
                                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                                regulatesregulation of epidermal cell differentiation +
                                                                                is-asebaceous gland cell differentiation
                                                                        part-ofepidermis morphogenesis +
                                                                        is-ahair follicle development +
                                                                        is-alimb epidermis development +
                                                                        negatively-regulatesnegative regulation of epidermis development +
                                                                        is-aplant epidermis development +
                                                                        positively-regulatespositive regulation of epidermis development +
                                                                        regulatesregulation of epidermis development +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation +
                                                        is-acumulus cell differentiation +
                                                        is-aendothelial cell differentiation +
                                                        is-aepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepithelial cell development +
                                                        is-aepithelial cell differentiation involved in embryonic placenta development +
                                                        is-aepithelial cell differentiation involved in kidney development +
                                                        is-aepithelial cell differentiation involved in prostate gland development +
                                                        is-aepithelial cell differentiation involved in salivary gland development +
                                                        part-ofepithelial cell fate commitment +
                                                        is-agranulosa cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-ahepatocyte differentiation +
                                                        is-aleading edge cell differentiation +
                                                        is-alens fiber cell differentiation +
                                                        is-alung epithelial cell differentiation +
                                                        is-aMalpighian tubule principal cell differentiation
                                                        is-aMalpighian tubule stellate cell differentiation
                                                        is-amammary gland epithelial cell differentiation +
                                                        is-amulti-ciliated epithelial cell differentiation
                                                        negatively-regulatesnegative regulation of epithelial cell differentiation +
                                                        is-aodontoblast differentiation +
                                                        is-apolarized epithelial cell differentiation +
                                                        positively-regulatespositive regulation of epithelial cell differentiation +
                                                        regulatesregulation of epithelial cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        is-aSertoli cell differentiation +
                                                        is-aureter epithelial cell differentiation


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aepithelial cell differentiation
                                                        is-acolumnar/cuboidal epithelial cell differentiation +
                                                        is-acumulus cell differentiation +
                                                        is-aendothelial cell differentiation +
                                                        is-aepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                part-ofepidermal cell fate specification +
                                                                is-ahair cell differentiation +
                                                                is-akeratinocyte differentiation +
                                                                is-alimb basal epidermal cell differentiation +
                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                regulatesregulation of epidermal cell differentiation +
                                                                is-asebaceous gland cell differentiation
                                                        part-ofepithelial cell development +
                                                        is-aepithelial cell differentiation involved in embryonic placenta development +
                                                        is-aepithelial cell differentiation involved in kidney development +
                                                        is-aepithelial cell differentiation involved in prostate gland development +
                                                        is-aepithelial cell differentiation involved in salivary gland development +
                                                        part-ofepithelial cell fate commitment +
                                                        is-agranulosa cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-ahepatocyte differentiation +
                                                        is-aleading edge cell differentiation +
                                                        is-alens fiber cell differentiation +
                                                        is-alung epithelial cell differentiation +
                                                        is-aMalpighian tubule principal cell differentiation
                                                        is-aMalpighian tubule stellate cell differentiation
                                                        is-amammary gland epithelial cell differentiation +
                                                        is-amulti-ciliated epithelial cell differentiation
                                                        negatively-regulatesnegative regulation of epithelial cell differentiation +
                                                        is-aodontoblast differentiation +
                                                        is-apolarized epithelial cell differentiation +
                                                        positively-regulatespositive regulation of epithelial cell differentiation +
                                                        regulatesregulation of epithelial cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        is-aSertoli cell differentiation +
                                                        is-aureter epithelial cell differentiation


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-askin development
                                                                part-ofepidermis development
                                                                        part-ofepidermal cell differentiation [GO:0009913] (152 genes, 205 annotations)
                                                                                part-ofepidermal cell fate specification +
                                                                                is-ahair cell differentiation +
                                                                                is-akeratinocyte differentiation +
                                                                                is-alimb basal epidermal cell differentiation +
                                                                                negatively-regulatesnegative regulation of epidermal cell differentiation +
                                                                                positively-regulatespositive regulation of epidermal cell differentiation +
                                                                                regulatesregulation of epidermal cell differentiation +
                                                                                is-asebaceous gland cell differentiation
                                                                        part-ofepidermis morphogenesis +
                                                                        is-ahair follicle development +
                                                                        is-alimb epidermis development +
                                                                        negatively-regulatesnegative regulation of epidermis development +
                                                                        is-aplant epidermis development +
                                                                        positively-regulatespositive regulation of epidermis development +
                                                                        regulatesregulation of epidermis development +


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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory