About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:pronucleus
GO id:GO:0045120
Definition:The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular membrane-bounded organelle
                                                                is-anucleus
                                                                        part-ofATF1-ATF4 transcription factor complex
                                                                        part-ofATF4-CREB1 transcription factor complex
                                                                        part-ofCKM complex
                                                                        part-ofCLOCK-BMAL transcription complex
                                                                        part-ofcondensed nuclear chromosome +
                                                                        part-ofcondensed nuclear chromosome, centromeric region +
                                                                        part-ofCry-Per complex
                                                                        part-ofCSL-Notch-Mastermind transcription factor complex
                                                                        is-agenerative cell nucleus
                                                                        is-agerm cell nucleus +
                                                                        is-ahorsetail nucleus +
                                                                        is-aleft nucleus
                                                                        is-alobed nucleus
                                                                        is-amacronucleus
                                                                        is-amegasporocyte nucleus +
                                                                        is-amicronucleus
                                                                        is-amicrosporocyte nucleus
                                                                        part-ofnuclear aryl hydrocarbon receptor complex
                                                                        part-ofnuclear chromatin +
                                                                        part-ofnuclear chromosome +
                                                                        part-ofnuclear chromosome, telomeric region +
                                                                        part-ofnuclear cohesin complex +
                                                                        part-ofnuclear condensin complex
                                                                        part-ofnuclear cyclin-dependent protein kinase holoenzyme complex +
                                                                        part-ofnuclear DNA replication factor C complex +
                                                                        part-ofnuclear DNA-directed RNA polymerase complex +
                                                                        part-ofnuclear exosome (RNase complex)
                                                                        part-ofnuclear inclusion body
                                                                        part-ofnuclear microtubule
                                                                        part-ofnuclear MIS12/MIND complex
                                                                        part-ofnuclear nucleosome
                                                                        part-ofnuclear part +
                                                                        part-ofnuclear pericentric heterochromatin
                                                                        part-ofnuclear proteasome complex +
                                                                        part-ofnuclear proteasome core complex +
                                                                        part-ofnuclear proteasome core complex, alpha-subunit complex
                                                                        part-ofnuclear proteasome core complex, beta-subunit complex
                                                                        part-ofnuclear proteasome regulatory particle +
                                                                        part-ofnuclear proteasome regulatory particle, base subcomplex
                                                                        part-ofnuclear proteasome regulatory particle, lid subcomplex
                                                                        part-ofnuclear rDNA heterochromatin
                                                                        part-ofnuclear replication fork +
                                                                        part-ofnuclear replisome +
                                                                        part-ofnuclear RNA-directed RNA polymerase complex
                                                                        part-ofnuclear SCF ubiquitin ligase complex
                                                                        part-ofnuclear subtelomeric heterochromatin
                                                                        part-ofnuclear telomere cap complex +
                                                                        part-ofnuclear transcription factor complex +
                                                                        part-ofnuclear transcriptional repressor complex +
                                                                        part-ofnuclear ubiquitin ligase complex +
                                                                        part-ofnucleosome disassembly/reassembly complex
                                                                        is-aprimary endosperm nucleus
                                                                        is-apronucleus [GO:0045120] (21 genes, 29 annotations)
                                                                                is-afemale pronucleus
                                                                                is-amale pronucleus
                                                                        is-aright nucleus
                                                                        part-ofU2AF
                                                                        part-ofupstream stimulatory factor complex


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-anucleus
                                                                part-ofATF1-ATF4 transcription factor complex
                                                                part-ofATF4-CREB1 transcription factor complex
                                                                part-ofCKM complex
                                                                part-ofCLOCK-BMAL transcription complex
                                                                part-ofcondensed nuclear chromosome +
                                                                part-ofcondensed nuclear chromosome, centromeric region +
                                                                part-ofCry-Per complex
                                                                part-ofCSL-Notch-Mastermind transcription factor complex
                                                                is-agenerative cell nucleus
                                                                is-agerm cell nucleus +
                                                                is-ahorsetail nucleus +
                                                                is-aleft nucleus
                                                                is-alobed nucleus
                                                                is-amacronucleus
                                                                is-amegasporocyte nucleus +
                                                                is-amicronucleus
                                                                is-amicrosporocyte nucleus
                                                                part-ofnuclear aryl hydrocarbon receptor complex
                                                                part-ofnuclear chromatin +
                                                                part-ofnuclear chromosome +
                                                                part-ofnuclear chromosome, telomeric region +
                                                                part-ofnuclear cohesin complex +
                                                                part-ofnuclear condensin complex
                                                                part-ofnuclear cyclin-dependent protein kinase holoenzyme complex +
                                                                part-ofnuclear DNA replication factor C complex +
                                                                part-ofnuclear DNA-directed RNA polymerase complex +
                                                                part-ofnuclear exosome (RNase complex)
                                                                part-ofnuclear inclusion body
                                                                part-ofnuclear microtubule
                                                                part-ofnuclear MIS12/MIND complex
                                                                part-ofnuclear nucleosome
                                                                part-ofnuclear part +
                                                                part-ofnuclear pericentric heterochromatin
                                                                part-ofnuclear proteasome complex +
                                                                part-ofnuclear proteasome core complex +
                                                                part-ofnuclear proteasome core complex, alpha-subunit complex
                                                                part-ofnuclear proteasome core complex, beta-subunit complex
                                                                part-ofnuclear proteasome regulatory particle +
                                                                part-ofnuclear proteasome regulatory particle, base subcomplex
                                                                part-ofnuclear proteasome regulatory particle, lid subcomplex
                                                                part-ofnuclear rDNA heterochromatin
                                                                part-ofnuclear replication fork +
                                                                part-ofnuclear replisome +
                                                                part-ofnuclear RNA-directed RNA polymerase complex
                                                                part-ofnuclear SCF ubiquitin ligase complex
                                                                part-ofnuclear subtelomeric heterochromatin
                                                                part-ofnuclear telomere cap complex +
                                                                part-ofnuclear transcription factor complex +
                                                                part-ofnuclear transcriptional repressor complex +
                                                                part-ofnuclear ubiquitin ligase complex +
                                                                part-ofnucleosome disassembly/reassembly complex
                                                                is-aprimary endosperm nucleus
                                                                is-apronucleus [GO:0045120] (21 genes, 29 annotations)
                                                                        is-afemale pronucleus
                                                                        is-amale pronucleus
                                                                is-aright nucleus
                                                                part-ofU2AF
                                                                part-ofupstream stimulatory factor complex


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-anucleus
                                                                part-ofATF1-ATF4 transcription factor complex
                                                                part-ofATF4-CREB1 transcription factor complex
                                                                part-ofCKM complex
                                                                part-ofCLOCK-BMAL transcription complex
                                                                part-ofcondensed nuclear chromosome +
                                                                part-ofcondensed nuclear chromosome, centromeric region +
                                                                part-ofCry-Per complex
                                                                part-ofCSL-Notch-Mastermind transcription factor complex
                                                                is-agenerative cell nucleus
                                                                is-agerm cell nucleus +
                                                                is-ahorsetail nucleus +
                                                                is-aleft nucleus
                                                                is-alobed nucleus
                                                                is-amacronucleus
                                                                is-amegasporocyte nucleus +
                                                                is-amicronucleus
                                                                is-amicrosporocyte nucleus
                                                                part-ofnuclear aryl hydrocarbon receptor complex
                                                                part-ofnuclear chromatin +
                                                                part-ofnuclear chromosome +
                                                                part-ofnuclear chromosome, telomeric region +
                                                                part-ofnuclear cohesin complex +
                                                                part-ofnuclear condensin complex
                                                                part-ofnuclear cyclin-dependent protein kinase holoenzyme complex +
                                                                part-ofnuclear DNA replication factor C complex +
                                                                part-ofnuclear DNA-directed RNA polymerase complex +
                                                                part-ofnuclear exosome (RNase complex)
                                                                part-ofnuclear inclusion body
                                                                part-ofnuclear microtubule
                                                                part-ofnuclear MIS12/MIND complex
                                                                part-ofnuclear nucleosome
                                                                part-ofnuclear part +
                                                                part-ofnuclear pericentric heterochromatin
                                                                part-ofnuclear proteasome complex +
                                                                part-ofnuclear proteasome core complex +
                                                                part-ofnuclear proteasome core complex, alpha-subunit complex
                                                                part-ofnuclear proteasome core complex, beta-subunit complex
                                                                part-ofnuclear proteasome regulatory particle +
                                                                part-ofnuclear proteasome regulatory particle, base subcomplex
                                                                part-ofnuclear proteasome regulatory particle, lid subcomplex
                                                                part-ofnuclear rDNA heterochromatin
                                                                part-ofnuclear replication fork +
                                                                part-ofnuclear replisome +
                                                                part-ofnuclear RNA-directed RNA polymerase complex
                                                                part-ofnuclear SCF ubiquitin ligase complex
                                                                part-ofnuclear subtelomeric heterochromatin
                                                                part-ofnuclear telomere cap complex +
                                                                part-ofnuclear transcription factor complex +
                                                                part-ofnuclear transcriptional repressor complex +
                                                                part-ofnuclear ubiquitin ligase complex +
                                                                part-ofnucleosome disassembly/reassembly complex
                                                                is-aprimary endosperm nucleus
                                                                is-apronucleus [GO:0045120] (21 genes, 29 annotations)
                                                                        is-afemale pronucleus
                                                                        is-amale pronucleus
                                                                is-aright nucleus
                                                                part-ofU2AF
                                                                part-ofupstream stimulatory factor complex


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular membrane-bounded organelle
                                                is-anucleus
                                                        part-ofATF1-ATF4 transcription factor complex
                                                        part-ofATF4-CREB1 transcription factor complex
                                                        part-ofCKM complex
                                                        part-ofCLOCK-BMAL transcription complex
                                                        part-ofcondensed nuclear chromosome +
                                                        part-ofcondensed nuclear chromosome, centromeric region +
                                                        part-ofCry-Per complex
                                                        part-ofCSL-Notch-Mastermind transcription factor complex
                                                        is-agenerative cell nucleus
                                                        is-agerm cell nucleus +
                                                        is-ahorsetail nucleus +
                                                        is-aleft nucleus
                                                        is-alobed nucleus
                                                        is-amacronucleus
                                                        is-amegasporocyte nucleus +
                                                        is-amicronucleus
                                                        is-amicrosporocyte nucleus
                                                        part-ofnuclear aryl hydrocarbon receptor complex
                                                        part-ofnuclear chromatin +
                                                        part-ofnuclear chromosome +
                                                        part-ofnuclear chromosome, telomeric region +
                                                        part-ofnuclear cohesin complex +
                                                        part-ofnuclear condensin complex
                                                        part-ofnuclear cyclin-dependent protein kinase holoenzyme complex +
                                                        part-ofnuclear DNA replication factor C complex +
                                                        part-ofnuclear DNA-directed RNA polymerase complex +
                                                        part-ofnuclear exosome (RNase complex)
                                                        part-ofnuclear inclusion body
                                                        part-ofnuclear microtubule
                                                        part-ofnuclear MIS12/MIND complex
                                                        part-ofnuclear nucleosome
                                                        part-ofnuclear part +
                                                        part-ofnuclear pericentric heterochromatin
                                                        part-ofnuclear proteasome complex +
                                                        part-ofnuclear proteasome core complex +
                                                        part-ofnuclear proteasome core complex, alpha-subunit complex
                                                        part-ofnuclear proteasome core complex, beta-subunit complex
                                                        part-ofnuclear proteasome regulatory particle +
                                                        part-ofnuclear proteasome regulatory particle, base subcomplex
                                                        part-ofnuclear proteasome regulatory particle, lid subcomplex
                                                        part-ofnuclear rDNA heterochromatin
                                                        part-ofnuclear replication fork +
                                                        part-ofnuclear replisome +
                                                        part-ofnuclear RNA-directed RNA polymerase complex
                                                        part-ofnuclear SCF ubiquitin ligase complex
                                                        part-ofnuclear subtelomeric heterochromatin
                                                        part-ofnuclear telomere cap complex +
                                                        part-ofnuclear transcription factor complex +
                                                        part-ofnuclear transcriptional repressor complex +
                                                        part-ofnuclear ubiquitin ligase complex +
                                                        part-ofnucleosome disassembly/reassembly complex
                                                        is-aprimary endosperm nucleus
                                                        is-apronucleus [GO:0045120] (21 genes, 29 annotations)
                                                                is-afemale pronucleus
                                                                is-amale pronucleus
                                                        is-aright nucleus
                                                        part-ofU2AF
                                                        part-ofupstream stimulatory factor complex


obsolete Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular membrane-bounded organelle
                                        is-anucleus
                                                part-ofATF1-ATF4 transcription factor complex
                                                part-ofATF4-CREB1 transcription factor complex
                                                part-ofCKM complex
                                                part-ofCLOCK-BMAL transcription complex
                                                part-ofcondensed nuclear chromosome +
                                                part-ofcondensed nuclear chromosome, centromeric region +
                                                part-ofCry-Per complex
                                                part-ofCSL-Notch-Mastermind transcription factor complex
                                                is-agenerative cell nucleus
                                                is-agerm cell nucleus +
                                                is-ahorsetail nucleus +
                                                is-aleft nucleus
                                                is-alobed nucleus
                                                is-amacronucleus
                                                is-amegasporocyte nucleus +
                                                is-amicronucleus
                                                is-amicrosporocyte nucleus
                                                part-ofnuclear aryl hydrocarbon receptor complex
                                                part-ofnuclear chromatin +
                                                part-ofnuclear chromosome +
                                                part-ofnuclear chromosome, telomeric region +
                                                part-ofnuclear cohesin complex +
                                                part-ofnuclear condensin complex
                                                part-ofnuclear cyclin-dependent protein kinase holoenzyme complex +
                                                part-ofnuclear DNA replication factor C complex +
                                                part-ofnuclear DNA-directed RNA polymerase complex +
                                                part-ofnuclear exosome (RNase complex)
                                                part-ofnuclear inclusion body
                                                part-ofnuclear microtubule
                                                part-ofnuclear MIS12/MIND complex
                                                part-ofnuclear nucleosome
                                                part-ofnuclear part +
                                                part-ofnuclear pericentric heterochromatin
                                                part-ofnuclear proteasome complex +
                                                part-ofnuclear proteasome core complex +
                                                part-ofnuclear proteasome core complex, alpha-subunit complex
                                                part-ofnuclear proteasome core complex, beta-subunit complex
                                                part-ofnuclear proteasome regulatory particle +
                                                part-ofnuclear proteasome regulatory particle, base subcomplex
                                                part-ofnuclear proteasome regulatory particle, lid subcomplex
                                                part-ofnuclear rDNA heterochromatin
                                                part-ofnuclear replication fork +
                                                part-ofnuclear replisome +
                                                part-ofnuclear RNA-directed RNA polymerase complex
                                                part-ofnuclear SCF ubiquitin ligase complex
                                                part-ofnuclear subtelomeric heterochromatin
                                                part-ofnuclear telomere cap complex +
                                                part-ofnuclear transcription factor complex +
                                                part-ofnuclear transcriptional repressor complex +
                                                part-ofnuclear ubiquitin ligase complex +
                                                part-ofnucleosome disassembly/reassembly complex
                                                is-aprimary endosperm nucleus
                                                is-apronucleus [GO:0045120] (21 genes, 29 annotations)
                                                        is-afemale pronucleus
                                                        is-amale pronucleus
                                                is-aright nucleus
                                                part-ofU2AF
                                                part-ofupstream stimulatory factor complex


obsolete Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-amembrane-bounded organelle
                                is-aintracellular membrane-bounded organelle
                                        is-anucleus
                                                part-ofATF1-ATF4 transcription factor complex
                                                part-ofATF4-CREB1 transcription factor complex
                                                part-ofCKM complex
                                                part-ofCLOCK-BMAL transcription complex
                                                part-ofcondensed nuclear chromosome +
                                                part-ofcondensed nuclear chromosome, centromeric region +
                                                part-ofCry-Per complex
                                                part-ofCSL-Notch-Mastermind transcription factor complex
                                                is-agenerative cell nucleus
                                                is-agerm cell nucleus +
                                                is-ahorsetail nucleus +
                                                is-aleft nucleus
                                                is-alobed nucleus
                                                is-amacronucleus
                                                is-amegasporocyte nucleus +
                                                is-amicronucleus
                                                is-amicrosporocyte nucleus
                                                part-ofnuclear aryl hydrocarbon receptor complex
                                                part-ofnuclear chromatin +
                                                part-ofnuclear chromosome +
                                                part-ofnuclear chromosome, telomeric region +
                                                part-ofnuclear cohesin complex +
                                                part-ofnuclear condensin complex
                                                part-ofnuclear cyclin-dependent protein kinase holoenzyme complex +
                                                part-ofnuclear DNA replication factor C complex +
                                                part-ofnuclear DNA-directed RNA polymerase complex +
                                                part-ofnuclear exosome (RNase complex)
                                                part-ofnuclear inclusion body
                                                part-ofnuclear microtubule
                                                part-ofnuclear MIS12/MIND complex
                                                part-ofnuclear nucleosome
                                                part-ofnuclear part +
                                                part-ofnuclear pericentric heterochromatin
                                                part-ofnuclear proteasome complex +
                                                part-ofnuclear proteasome core complex +
                                                part-ofnuclear proteasome core complex, alpha-subunit complex
                                                part-ofnuclear proteasome core complex, beta-subunit complex
                                                part-ofnuclear proteasome regulatory particle +
                                                part-ofnuclear proteasome regulatory particle, base subcomplex
                                                part-ofnuclear proteasome regulatory particle, lid subcomplex
                                                part-ofnuclear rDNA heterochromatin
                                                part-ofnuclear replication fork +
                                                part-ofnuclear replisome +
                                                part-ofnuclear RNA-directed RNA polymerase complex
                                                part-ofnuclear SCF ubiquitin ligase complex
                                                part-ofnuclear subtelomeric heterochromatin
                                                part-ofnuclear telomere cap complex +
                                                part-ofnuclear transcription factor complex +
                                                part-ofnuclear transcriptional repressor complex +
                                                part-ofnuclear ubiquitin ligase complex +
                                                part-ofnucleosome disassembly/reassembly complex
                                                is-aprimary endosperm nucleus
                                                is-apronucleus [GO:0045120] (21 genes, 29 annotations)
                                                        is-afemale pronucleus
                                                        is-amale pronucleus
                                                is-aright nucleus
                                                part-ofU2AF
                                                part-ofupstream stimulatory factor complex


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory