| GO term: | G1/S transition of mitotic cell cycle |
| GO id: | GO:0000082 |
| Definition: | The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. |
| Number of paths to term: | 12 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processcellular processsingle-organism cellular processcell cyclecell cycle processcell cycle phaseinterphaseinterphase of mitotic cell cycleG1 phase of mitotic cell cycle +G1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2 phase of mitotic cell cycle +S phase of mitotic cell cycle +biological_processcellular processsingle-organism cellular processcell cyclecell cycle processcell cycle phase transitionmitotic cell cycle phase transitionG1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2/M transition of mitotic cell cycle +metaphase/anaphase transition of mitotic cell cycle +negative regulation of mitotic cell cycle phase transition +positive regulation of mitotic cell cycle phase transition +regulation of mitotic cell cycle phase transition +biological_processcellular processsingle-organism cellular processcell cyclemitotic cell cycleinterphase of mitotic cell cycleG1 phase of mitotic cell cycle +G1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2 phase of mitotic cell cycle +S phase of mitotic cell cycle +biological_processcellular processsingle-organism cellular processcell cyclemitotic cell cyclemitotic cell cycle phase transitionG1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2/M transition of mitotic cell cycle +metaphase/anaphase transition of mitotic cell cycle +negative regulation of mitotic cell cycle phase transition +positive regulation of mitotic cell cycle phase transition +regulation of mitotic cell cycle phase transition +biological_processcellular processsingle-organism cellular processcell cycle processcell cycle phaseinterphaseinterphase of mitotic cell cycleG1 phase of mitotic cell cycle +G1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2 phase of mitotic cell cycle +S phase of mitotic cell cycle +biological_processcellular processsingle-organism cellular processcell cycle processcell cycle phase transitionmitotic cell cycle phase transitionG1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2/M transition of mitotic cell cycle +metaphase/anaphase transition of mitotic cell cycle +negative regulation of mitotic cell cycle phase transition +positive regulation of mitotic cell cycle phase transition +regulation of mitotic cell cycle phase transition +biological_processsingle-organism processsingle-organism cellular processcell cyclecell cycle processcell cycle phaseinterphaseinterphase of mitotic cell cycleG1 phase of mitotic cell cycle +G1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2 phase of mitotic cell cycle +S phase of mitotic cell cycle +biological_processsingle-organism processsingle-organism cellular processcell cyclecell cycle processcell cycle phase transitionmitotic cell cycle phase transitionG1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2/M transition of mitotic cell cycle +metaphase/anaphase transition of mitotic cell cycle +negative regulation of mitotic cell cycle phase transition +positive regulation of mitotic cell cycle phase transition +regulation of mitotic cell cycle phase transition +biological_processsingle-organism processsingle-organism cellular processcell cyclemitotic cell cycleinterphase of mitotic cell cycleG1 phase of mitotic cell cycle +G1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2 phase of mitotic cell cycle +S phase of mitotic cell cycle +biological_processsingle-organism processsingle-organism cellular processcell cyclemitotic cell cyclemitotic cell cycle phase transitionG1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2/M transition of mitotic cell cycle +metaphase/anaphase transition of mitotic cell cycle +negative regulation of mitotic cell cycle phase transition +positive regulation of mitotic cell cycle phase transition +regulation of mitotic cell cycle phase transition +biological_processsingle-organism processsingle-organism cellular processcell cycle processcell cycle phaseinterphaseinterphase of mitotic cell cycleG1 phase of mitotic cell cycle +G1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2 phase of mitotic cell cycle +S phase of mitotic cell cycle +biological_processsingle-organism processsingle-organism cellular processcell cycle processcell cycle phase transitionmitotic cell cycle phase transitionG1/S transition of mitotic cell cycle [GO:0000082] (121 genes, 143 annotations)negative regulation of G1/S transition of mitotic cell cycle +positive regulation of G1/S transition of mitotic cell cycle +regulation of G1/S transition of mitotic cell cycle +regulation of transcription involved in G1/S phase of mitotic cell cycle +G2/M transition of mitotic cell cycle +metaphase/anaphase transition of mitotic cell cycle +negative regulation of mitotic cell cycle phase transition +positive regulation of mitotic cell cycle phase transition +regulation of mitotic cell cycle phase transition +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc 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last database update 05/22/2013 MGI 5.13 |
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