| GO term: | transcription corepressor activity |
| Synonym: | transcription co-repressor activity |
| GO id: | GO:0003714 |
| Definition: | Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionprotein binding transcription factor activitytranscription factor binding transcription factor activitytranscription cofactor activityRNA polymerase II transcription cofactor activity +transcription coactivator activity +transcription corepressor activity [GO:0003714] (130 genes, 163 annotations)RNA polymerase II transcription corepressor activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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