| GO term: | negative regulation of gene expression |
| GO id: | GO:0010629 |
| Definition: | Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. |
| Number of paths to term: | 18 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processnegative regulation of biological processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processbiological regulationregulation of biological processregulation of metabolic processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processbiological regulationregulation of biological processregulation of metabolic processregulation of macromolecule metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processbiological regulationregulation of biological processregulation of metabolic processregulation of macromolecule metabolic processregulation of gene expressioncircadian regulation of gene expressionnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +positive regulation of gene expression +posttranscriptional regulation of gene expression +pre-B cell allelic exclusionregulation of gene expression involved in extracellular matrix organization +regulation of gene expression, epigenetic +regulation of histone gene expression +regulation of mRNA processing +regulation of production of small RNA involved in gene silencing by RNA +regulation of protein processing +regulation of rhodopsin gene expression +regulation of RNA splicing +regulation of rRNA processing +regulation of transcription, DNA-dependent +regulation of tRNA processing +signal transduction involved in regulation of gene expressionbiological_processmetabolic processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processgene expressiongene expression involved in extracellular matrix organization +negative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +positive regulation of gene expression +pre-B cell receptor expressionprotein maturation +regulation of gene expression +RNA processing +transcription, DNA-dependent +translation +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processgene expressionregulation of gene expressioncircadian regulation of gene expressionnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +positive regulation of gene expression +posttranscriptional regulation of gene expression +pre-B cell allelic exclusionregulation of gene expression involved in extracellular matrix organization +regulation of gene expression, epigenetic +regulation of histone gene expression +regulation of mRNA processing +regulation of production of small RNA involved in gene silencing by RNA +regulation of protein processing +regulation of rhodopsin gene expression +regulation of RNA splicing +regulation of rRNA processing +regulation of transcription, DNA-dependent +regulation of tRNA processing +signal transduction involved in regulation of gene expressionbiological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processregulation of macromolecule metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processregulation of macromolecule metabolic processregulation of gene expressioncircadian regulation of gene expressionnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +positive regulation of gene expression +posttranscriptional regulation of gene expression +pre-B cell allelic exclusionregulation of gene expression involved in extracellular matrix organization +regulation of gene expression, epigenetic +regulation of histone gene expression +regulation of mRNA processing +regulation of production of small RNA involved in gene silencing by RNA +regulation of protein processing +regulation of rhodopsin gene expression +regulation of RNA splicing +regulation of rRNA processing +regulation of transcription, DNA-dependent +regulation of tRNA processing +signal transduction involved in regulation of gene expressionbiological_processmetabolic processregulation of metabolic processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processmetabolic processregulation of metabolic processregulation of macromolecule metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processmetabolic processregulation of metabolic processregulation of macromolecule metabolic processregulation of gene expressioncircadian regulation of gene expressionnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +positive regulation of gene expression +posttranscriptional regulation of gene expression +pre-B cell allelic exclusionregulation of gene expression involved in extracellular matrix organization +regulation of gene expression, epigenetic +regulation of histone gene expression +regulation of mRNA processing +regulation of production of small RNA involved in gene silencing by RNA +regulation of protein processing +regulation of rhodopsin gene expression +regulation of RNA splicing +regulation of rRNA processing +regulation of transcription, DNA-dependent +regulation of tRNA processing +signal transduction involved in regulation of gene expressionbiological_processnegative regulation of biological processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processregulation of biological processnegative regulation of biological processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processregulation of biological processregulation of metabolic processnegative regulation of metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processregulation of biological processregulation of metabolic processregulation of macromolecule metabolic processnegative regulation of macromolecule metabolic processnegative regulation of amylopectin metabolic process +negative regulation of cell wall polysaccharide catabolic process +negative regulation of cellodextrin metabolic process +negative regulation of cellotriose metabolic process +negative regulation of cellulose catabolic processnegative regulation of collagen metabolic process +negative regulation of cyclodextrin metabolic process +negative regulation of DNA metabolic process +negative regulation of galactoglucomannan catabolic processnegative regulation of galactomannan catabolic processnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +negative regulation of glucomannan catabolic processnegative regulation of glycogen metabolic process +negative regulation of glycolysisnegative regulation of hemicellulose catabolic process +negative regulation of macromolecule biosynthetic process +negative regulation of pectin catabolic processnegative regulation of protein metabolic process +negative regulation of receptor catabolic process +negative regulation of receptor internalizationnegative regulation of receptor recyclingnegative regulation of RNA metabolic process +negative regulation of starch metabolic process +negative regulation of xyloglucan metabolic process +regulation of UDP-glucose catabolic process +biological_processregulation of biological processregulation of metabolic processregulation of macromolecule metabolic processregulation of gene expressioncircadian regulation of gene expressionnegative regulation of gene expression [GO:0010629] (982 genes, 1601 annotations)gene silencing +negative regulation of gene expression involved in extracellular matrix organizationnegative regulation of gene expression, epigenetic +negative regulation of histone gene expressionnegative regulation of rhodopsin gene expressionnegative regulation of transcription, DNA-dependent +positive regulation of gene expression +posttranscriptional regulation of gene expression +pre-B cell allelic exclusionregulation of gene expression involved in extracellular matrix organization +regulation of gene expression, epigenetic +regulation of histone gene expression +regulation of mRNA processing +regulation of production of small RNA involved in gene silencing by RNA +regulation of protein processing +regulation of rhodopsin gene expression +regulation of RNA splicing +regulation of rRNA processing +regulation of transcription, DNA-dependent +regulation of tRNA processing +signal transduction involved in regulation of gene expressionMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
||
|
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support. |
last database update 05/08/2013 MGI 5.13 |
|
|
|
||
Analysis Tools