About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:transcription coactivator activity
Synonym: transcription co-activator activity
GO id:GO:0003713
Definition:Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-aprotein binding transcription factor activity
                        is-atranscription factor binding transcription factor activity
                                is-atranscription cofactor activity
                                        is-aRNA polymerase II transcription cofactor activity +
                                        is-atranscription coactivator activity [GO:0003713] (207 genes, 274 annotations)
                                                is-acAMP response element binding protein binding
                                                is-aligand-dependent nuclear receptor transcription coactivator activity +
                                                is-aRNA polymerase II transcription coactivator activity +
                                        is-atranscription corepressor activity +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/21/2014
MGI 5.20
The Jackson Laboratory