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Term Detail
GO term:transcription coactivator activity
Synonym: transcription co-activator activity
Synonym: transcription coactivator activity
GO id:GO:0003713
Definition:Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-atranscription factor activity, protein binding
                        is-atranscription factor activity, transcription factor binding
                                is-atranscription cofactor activity
                                        is-aRNA polymerase II transcription cofactor activity +
                                        is-atranscription coactivator activity [GO:0003713] (239 genes, 337 annotations)
                                                is-aligand-dependent nuclear receptor transcription coactivator activity +
                                                is-aRNA polymerase II transcription coactivator activity +
                                        is-atranscription corepressor activity +

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory