| GO term: | transcription coactivator activity |
| Synonym: | transcription co-activator activity |
| GO id: | GO:0003713 |
| Definition: | Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionprotein binding transcription factor activitytranscription factor binding transcription factor activitytranscription cofactor activityRNA polymerase II transcription cofactor activity +transcription coactivator activity [GO:0003713] (192 genes, 257 annotations)cAMP response element binding protein bindingligand-dependent nuclear receptor transcription coactivator activity +RNA polymerase II transcription coactivator activity +transcription corepressor activity +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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