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Gene Ontology Browser
Term Detail
GO term:sequence-specific DNA binding
Synonym: sequence specific DNA binding
GO id:GO:0043565
Definition:Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-abinding
                        is-aheterocyclic compound binding
                                is-anucleic acid binding
                                        is-aDNA binding
                                                is-abase pairing with DNA +
                                                is-adamaged DNA binding +
                                                is-aDNA binding, bending +
                                                is-aDNA clamp loader activity
                                                is-arecombination hotspot binding
                                                is-aregulatory region DNA binding +
                                                is-asequence-specific DNA binding [GO:0043565] (731 genes, 1179 annotations)
                                                        is-aAT DNA binding
                                                        is-acentromeric DNA binding
                                                        is-aDNA replication origin binding
                                                        is-amethyl-CpG binding
                                                        is-aP-element binding
                                                        is-apurine-rich negative regulatory element binding
                                                        is-arDNA binding +
                                                        is-areplication fork barrier binding +
                                                        is-asatellite DNA binding +
                                                        is-asequence-specific DNA binding, bending +
                                                        is-atDNA binding
                                                        is-atelomeric DNA binding +
                                                        is-atranscription regulatory region sequence-specific DNA binding +
                                                        is-aunmethylated CpG binding
                                                is-astructure-specific DNA binding +


Gene_Ontology
        is-amolecular_function
                is-abinding
                        is-aorganic cyclic compound binding
                                is-anucleic acid binding
                                        is-aDNA binding
                                                is-abase pairing with DNA +
                                                is-adamaged DNA binding +
                                                is-aDNA binding, bending +
                                                is-aDNA clamp loader activity
                                                is-arecombination hotspot binding
                                                is-aregulatory region DNA binding +
                                                is-asequence-specific DNA binding [GO:0043565] (731 genes, 1179 annotations)
                                                        is-aAT DNA binding
                                                        is-acentromeric DNA binding
                                                        is-aDNA replication origin binding
                                                        is-amethyl-CpG binding
                                                        is-aP-element binding
                                                        is-apurine-rich negative regulatory element binding
                                                        is-arDNA binding +
                                                        is-areplication fork barrier binding +
                                                        is-asatellite DNA binding +
                                                        is-asequence-specific DNA binding, bending +
                                                        is-atDNA binding
                                                        is-atelomeric DNA binding +
                                                        is-atranscription regulatory region sequence-specific DNA binding +
                                                        is-aunmethylated CpG binding
                                                is-astructure-specific DNA binding +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory