MGI 5.13 - Gene Ontology Browser

Gene Ontology Browser
Term Detail

GO term:	sequence-specific DNA binding
Synonym:	sequence specific DNA binding
GO id:	GO:0043565
Definition:	Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
Number of paths to term:	2

denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship

Gene_Ontology

molecular_function

binding

heterocyclic compound binding

nucleic acid binding

DNA binding

base pairing with DNA +

damaged DNA binding +

DNA binding, bending +

DNA clamp loader activity

DNA topoisomerase activity +

DNA translocase activity +

recombination hotspot binding

regulatory region DNA binding +

sequence-specific DNA binding [GO:0043565] (653 genes, 905 annotations)

AT DNA binding

centromeric DNA binding

DNA replication origin binding

methyl-CpG binding

P-element binding

purine-rich negative regulatory element binding

rDNA binding +

replication fork barrier binding +

satellite DNA binding +

sequence-specific DNA binding, bending +

tDNA binding

telomeric DNA binding +

transcription regulatory region sequence-specific DNA binding +

unmethylated CpG binding

structure-specific DNA binding +