Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cdk5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CDK5
- Mouse genes Cdk5
- Rat genes Cdk5
- Zfish genes cdk5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030549	acetylcholine receptor activator activity	Cdk5	IDA		Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:11675505\|RGD:69667
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:12691662\|RGD:1598431
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:14502288\|RGD:734740
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:15286209\|RGD:1598428
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:15331630\|RGD:1598417
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:15471880\|RGD:1598416
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:15592431\|RGD:1598414
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:15992363\|RGD:1598412
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:18498738\|RGD:8553496
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	cdk5	IMP	ZFIN:ZDB-MRPHLNO-100511-10	Zfish	PMID:19523926
Molecular Function	GO:0008092	cytoskeletal protein binding	Cdk5	IPI	UniProtKB:P12036	Rat	PMID:9313898\|RGD:8553816
Molecular Function	GO:0046875	ephrin receptor binding	Cdk5	IPI	UniProtKB:D3ZZK3	Rat	PMID:17143272\|RGD:8554385
Molecular Function	GO:0005176	ErbB-2 class receptor binding	Cdk5	IDA		Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0043125	ErbB-3 class receptor binding	Cdk5	IDA		Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0035173	histone kinase activity	Cdk5	IDA		Rat	PMID:16407116\|RGD:13782383
Molecular Function	GO:0035173	histone kinase activity	cdk5	IMP		Zfish	PMID:17178437
Molecular Function	GO:0035173	histone kinase activity	cdk5	IDA		Zfish	PMID:16911583
Molecular Function	GO:0051879	Hsp90 protein binding	Cdk5	IPI	UniProtKB:P11499	Mouse	MGI:MGI:6148636\|PMID:17517623
Molecular Function	GO:0016301	kinase activity	Cdk5	IDA		Rat	PMID:8846918\|RGD:8554279
Molecular Function	GO:0002039	p53 binding	Cdk5	IPI	PR:P02340	Mouse	PMID:17591690
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:12223541
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:14521924
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:15689152
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P38936	Human	PMID:15890360
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:15890360
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:20133653
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q8TDN4	Human	PMID:20559324
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:21220307
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P37231-2	Human	PMID:22078880
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30281	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P38936	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q8TDN4	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P09936	Human	PMID:23543736
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:23543736
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30281	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P38936	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q8TDN4	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P24863	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q14094	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q8TDN4	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30281	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q8TDN4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P38936	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:A6NLX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30281	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q14094	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q5MJ70	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30279	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q8TDN4	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P20226	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P61158	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P62937	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q9UJC3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q9Y6R0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P30281	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:P46527	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:A6NLX3	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CDK5	IPI	UniProtKB:Q15078	Human	PMID:8090221
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61809	Mouse	MGI:MGI:5512836\|PMID:18325333
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61809	Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61809	Mouse	MGI:MGI:5918092\|PMID:17341134
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P70424\|UniProtKB:Q61526	Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:Q9R1C8	Mouse	MGI:MGI:5607347\|PMID:25078650
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61809	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	PR:P42227	Mouse	PMID:15096606
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	PR:O35350	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	PR:O70589	Mouse	PMID:18054859
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	PR:Q01097	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	PR:P61809	Mouse	PMID:12496365
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	PR:P42669	Mouse	PMID:12972605
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	RGD:3785	Rat	PMID:12963086\|RGD:1598430
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61810	Rat	PMID:17036052\|RGD:13432229
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61810	Rat	PMID:17341134\|RGD:13432345
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:Q03351	Rat	PMID:17341134\|RGD:13432345
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:Q16620	Rat	PMID:17341134\|RGD:13432345
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:Q63604	Rat	PMID:17341134\|RGD:13432345
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:O35412	Rat	PMID:18498738\|RGD:8553496
Molecular Function	GO:0005515	protein binding	Cdk5	IPI	UniProtKB:P61810	Rat	PMID:8846918\|RGD:8554279
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:17194758
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:9126296
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:11517264
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:15123626
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:12077184
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16203963
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IMP	MGI:MGI:4941828	Mouse	PMID:18054859
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IMP		Mouse	PMID:14769920
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:9202329
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:11226314
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:12372285
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Mouse	PMID:11343650
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IMP	MGI:MGI:2179066	Mouse	PMID:18054859
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Rat	PMID:12084709\|RGD:632377
Molecular Function	GO:0004672	protein kinase activity	Cdk5	IDA		Rat	PMID:17202132\|RGD:8553329
Molecular Function	GO:0019901	protein kinase binding	Cdk5	IPI	RGD:1584969	Rat	PMID:19700222\|RGD:8693570
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK5	IDA		Human	PMID:20357208
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK5	IDA		Human	PMID:21145489
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk5	IDA		Mouse	PMID:12941275
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk5	IDA		Mouse	PMID:18054859
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk5	IDA		Mouse	PMID:15489224
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:15994305\|RGD:8553752
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk5	IDA		Rat	PMID:8662984\|RGD:632374
Molecular Function	GO:0050321	tau-protein kinase activity	Cdk5	IDA		Rat	PMID:15994305\|RGD:8553752
Cellular Component	GO:0030424	axon	Cdk5	IDA		Mouse	PMID:3627430
Cellular Component	GO:0030424	axon	Cdk5	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0030054	cell junction	CDK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	CDK5	IPI		Human	PMID:16039528
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	Cdk5	IPI		Mouse	MGI:MGI:5512836\|PMID:18325333
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Mouse	PMID:15096606
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Mouse	PMID:9191048
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Mouse	PMID:3627430
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Rat	PMID:10683146\|RGD:13601989
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Rat	PMID:12691662\|RGD:1598431
Cellular Component	GO:0005737	cytoplasm	Cdk5	IDA		Rat	PMID:17491008\|RGD:13461746
Cellular Component	GO:0005856	cytoskeleton	Cdk5	IDA		Rat	PMID:12963086\|RGD:1598430
Cellular Component	GO:0005829	cytosol	Cdk5	IDA		Mouse	PMID:9202329
Cellular Component	GO:0005829	cytosol	Cdk5	IDA		Mouse	PMID:12496365
Cellular Component	GO:0030425	dendrite	Cdk5	IDA		Rat	PMID:12223541\|RGD:8554161
Cellular Component	GO:0030425	dendrite	Cdk5	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0030175	filopodium	Cdk5	IDA		Mouse	PMID:12496365
Cellular Component	GO:0098978	glutamatergic synapse	Cdk5	EXP		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0098978	glutamatergic synapse	Cdk5	IDA		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0098978	glutamatergic synapse	Cdk5	IMP		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0030426	growth cone	Cdk5	IDA		Rat	PMID:10683146\|RGD:13601989
Cellular Component	GO:0030426	growth cone	Cdk5	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0030027	lamellipodium	Cdk5	IDA		Mouse	PMID:12496365
Cellular Component	GO:0016020	membrane	Cdk5	IDA		Rat	PMID:10683146\|RGD:13601989
Cellular Component	GO:0016020	membrane	Cdk5	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0016020	membrane	Cdk5	IDA		Rat	PMID:17671990\|RGD:13782381
Cellular Component	GO:0005874	microtubule	Cdk5	IDA		Rat	PMID:17491008\|RGD:13461746
Cellular Component	GO:0031594	neuromuscular junction	Cdk5	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0043005	neuron projection	Cdk5	IDA		Rat	PMID:10683146\|RGD:13601989
Cellular Component	GO:0043025	neuronal cell body	Cdk5	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0005654	nucleoplasm	CDK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Cdk5	IDA		Mouse	PMID:9191048
Cellular Component	GO:0005634	nucleus	Cdk5	IDA		Mouse	PMID:15096606
Cellular Component	GO:0005634	nucleus	Cdk5	IDA		Mouse	PMID:17591690
Cellular Component	GO:0005634	nucleus	Cdk5	IDA		Mouse	PMID:8891282
Cellular Component	GO:0005634	nucleus	Cdk5	IDA		Rat	PMID:12691662\|RGD:1598431
Cellular Component	GO:0005634	nucleus	Cdk5	IDA		Rat	PMID:16192386\|RGD:8553388
Cellular Component	GO:0005886	plasma membrane	CDK5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098794	postsynapse	Cdk5	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0014069	postsynaptic density	Cdk5	IDA		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0098793	presynapse	Cdk5	IMP		Rat	PMID:23699505\|RGD:13792535
Cellular Component	GO:0016533	protein kinase 5 complex	CDK5	IPI		Human	PMID:15689152
Cellular Component	GO:0016533	protein kinase 5 complex	CDK5	IPI		Human	PMID:16039528
Cellular Component	GO:0016533	protein kinase 5 complex	Cdk5	IPI		Mouse	MGI:MGI:5512836\|PMID:18325333
Cellular Component	GO:0016533	protein kinase 5 complex	Cdk5	IDA		Rat	PMID:8662984\|RGD:632374
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cdk5	EXP		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cdk5	IDA		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cdk5	IMP		Rat	PMID:17143272\|RGD:8554385
Biological Process	GO:0006915	apoptotic process	Cdk5	IDA		Mouse	PMID:9126296
Biological Process	GO:0008306	associative learning	Cdk5	IMP		Mouse	PMID:11978846
Biological Process	GO:0007409	axonogenesis	Cdk5	IMP		Mouse	PMID:11163260
Biological Process	GO:0048148	behavioral response to cocaine	Cdk5	IMP	MGI:MGI:3531299,MGI:MGI:3720892	Mouse	PMID:18032670
Biological Process	GO:0070509	calcium ion import	Cdk5	IMP		Mouse	PMID:18054859
Biological Process	GO:0016477	cell migration	Cdk5	IDA		Mouse	PMID:12496365
Biological Process	GO:0016477	cell migration	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:17694053
Biological Process	GO:0016477	cell migration	Cdk5	IMP	MGI:MGI:1928281,MGI:MGI:3043819	Mouse	PMID:18032654
Biological Process	GO:0007160	cell-matrix adhesion	Cdk5	IDA		Mouse	PMID:12496365
Biological Process	GO:1904646	cellular response to amyloid-beta	Cdk5	IDA		Rat	PMID:26224839\|RGD:11576284
Biological Process	GO:0021954	central nervous system neuron development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:8855328
Biological Process	GO:0021954	central nervous system neuron development	cdk5	IMP	ZFIN:ZDB-MRPHLNO-100511-10	Zfish	PMID:19523926
Biological Process	GO:0021695	cerebellar cortex development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:8855328
Biological Process	GO:0021697	cerebellar cortex formation	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:10407039
Biological Process	GO:0021549	cerebellum development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:11226314
Biological Process	GO:0021987	cerebral cortex development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:9698328
Biological Process	GO:0022038	corpus callosum development	Cdk5	IMP	MGI:MGI:1928281,MGI:MGI:3043819	Mouse	PMID:18032654
Biological Process	GO:0030866	cortical actin cytoskeleton organization	Cdk5	IMP		Rat	PMID:15331630\|RGD:1598417
Biological Process	GO:0048813	dendrite morphogenesis	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:12372285
Biological Process	GO:0048813	dendrite morphogenesis	Cdk5	IMP		Mouse	PMID:17143272
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	cdk5	IMP	ZFIN:ZDB-MRPHLNO-090106-1	Zfish	PMID:18753621
Biological Process	GO:0051649	establishment of localization in cell	Cdk5	IMP		Mouse	PMID:18054859
Biological Process	GO:0060079	excitatory postsynaptic potential	Cdk5	IMP	MGI:MGI:3720892,MGI:MGI:3720937	Mouse	PMID:17529984
Biological Process	GO:0006887	exocytosis	Cdk5	IMP		Rat	PMID:15331630\|RGD:1598417
Biological Process	GO:0030900	forebrain development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:17694053
Biological Process	GO:0021766	hippocampus development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:11517264
Biological Process	GO:0016570	histone modification	cdk5	IMP		Zfish	PMID:17178437\|ZFIN:ZDB-PUB-061229-13
Biological Process	GO:0006886	intracellular protein transport	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:8855328
Biological Process	GO:0021819	layer formation in cerebral cortex	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:11517264
Biological Process	GO:0007005	mitochondrion organization	Cdk5	IMP		Rat	PMID:28153522\|RGD:13506926
Biological Process	GO:0008045	motor neuron axon guidance	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16203963
Biological Process	GO:0030517	negative regulation of axon extension	Cdk5	IGI	MGI:MGI:1197518	Mouse	PMID:22573681
Biological Process	GO:0045786	negative regulation of cell cycle	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16237170
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CDK5	IMP		Human	PMID:20357208
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	cdk5	IMP		Zfish	PMID:16911583
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	cdk5	IDA		Zfish	PMID:16911583
Biological Process	GO:1901215	negative regulation of neuron death	CDK5	IDA		Human	PMID:24548080
Biological Process	GO:0046826	negative regulation of protein export from nucleus	Cdk5	IMP		Mouse	PMID:17591690
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Cdk5	IMP		Mouse	PMID:17591690
Biological Process	GO:0045861	negative regulation of proteolysis	CDK5	IMP		Human	PMID:24548080
Biological Process	GO:0031914	negative regulation of synaptic plasticity	Cdk5	IMP	MGI:MGI:3720892,MGI:MGI:3720937	Mouse	PMID:17529984
Biological Process	GO:0051402	neuron apoptotic process	Cdk5	IMP		Mouse	PMID:17591690
Biological Process	GO:0051402	neuron apoptotic process	Cdk5	IMP		Rat	PMID:15592431\|RGD:1598414
Biological Process	GO:0030182	neuron differentiation	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16237170
Biological Process	GO:0030182	neuron differentiation	Cdk5	IDA		Rat	PMID:8846918\|RGD:8554279
Biological Process	GO:0030182	neuron differentiation	cdk5	IMP	ZFIN:ZDB-MRPHLNO-090106-1	Zfish	PMID:18753621
Biological Process	GO:0001764	neuron migration	Cdk5	IMP	MGI:MGI:3043819,MGI:MGI:3043822	Mouse	PMID:15067135
Biological Process	GO:0001764	neuron migration	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:10407039
Biological Process	GO:0031175	neuron projection development	Cdk5	IMP		Rat	PMID:8846918\|RGD:8554279
Biological Process	GO:0048812	neuron projection morphogenesis	Cdk5	IMP		Rat	PMID:12535933\|RGD:1598432
Biological Process	GO:0006913	nucleocytoplasmic transport	Cdk5	IMP		Rat	PMID:16887799\|RGD:2311183
Biological Process	GO:0048709	oligodendrocyte differentiation	CDK5	IDA		Human	PMID:18042622
Biological Process	GO:0021634	optic nerve formation	cdk5	IMP	ZFIN:ZDB-MRPHLNO-090106-1	Zfish	PMID:18753621
Biological Process	GO:0018105	peptidyl-serine phosphorylation	CDK5	IDA		Human	PMID:21145489
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Cdk5	IMP		Mouse	MGI:MGI:6094501\|PMID:24607229
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Cdk5	IMP	MGI:MGI:2179066	Mouse	PMID:18054859
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Cdk5	IMP	MGI:MGI:4941828	Mouse	PMID:18054859
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Cdk5	IDA		Mouse	PMID:18054859
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Cdk5	IDA		Rat	PMID:12691662\|RGD:1598431
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Cdk5	IDA		Rat	PMID:14502288\|RGD:734740
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Cdk5	IMP		Mouse	MGI:MGI:6094501\|PMID:24607229
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Cdk5	IDA		Mouse	PMID:18054859
Biological Process	GO:0048935	peripheral nervous system neuron development	cdk5	IMP		Zfish	PMID:17178437
Biological Process	GO:0016310	phosphorylation	CDK5	IDA		Human	PMID:20357208
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Cdk5	IDA		Mouse	PMID:15123626
Biological Process	GO:0034352	positive regulation of glial cell apoptotic process	Cdk5	IMP		Rat	PMID:28153522\|RGD:13506926
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Cdk5	IDA		Rat	PMID:16192386\|RGD:8553388
Biological Process	GO:1901216	positive regulation of neuron death	Cdk5	IMP		Rat	PMID:19151707\|RGD:10053571
Biological Process	GO:0099533	positive regulation of presynaptic cytosolic calcium concentration	Cdk5	IMP		Rat	PMID:23699505\|RGD:13792535
Biological Process	GO:0032092	positive regulation of protein binding	Cdk5	IMP	MGI:MGI:4941830	Mouse	PMID:18054859
Biological Process	GO:0045860	positive regulation of protein kinase activity	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16203963
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Cdk5	IMP		Rat	PMID:28153522\|RGD:13506926
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Cdk5	IMP	MGI:MGI:4941830	Mouse	PMID:18054859
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	Cdk5	IMP		Rat	PMID:23699505\|RGD:13792535
Biological Process	GO:0046777	protein autophosphorylation	Cdk5	IDA		Rat	PMID:15992363\|RGD:1598412
Biological Process	GO:0035418	protein localization to synapse	Cdk5	IMP		Mouse	PMID:18054859
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IMP		Mouse	PMID:17591690
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IGI	MGI:MGI:894678	Mouse	PMID:17060449
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Mouse	PMID:17194758
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Mouse	PMID:11517264
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Mouse	PMID:15123626
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Mouse	PMID:12372285
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Mouse	PMID:15489224
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Rat	PMID:17202132\|RGD:8553329
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Rat	PMID:15331630\|RGD:1598417
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Rat	PMID:15592431\|RGD:1598414
Biological Process	GO:0006468	protein phosphorylation	Cdk5	IDA		Rat	PMID:8662984\|RGD:632374
Biological Process	GO:0032801	receptor catabolic process	Cdk5	IMP	MGI:MGI:3720892,MGI:MGI:3720937	Mouse	PMID:17529984
Biological Process	GO:0043113	receptor clustering	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16203963
Biological Process	GO:0045055	regulated exocytosis	Cdk5	IMP		Rat	PMID:15331630\|RGD:1598417
Biological Process	GO:0030334	regulation of cell migration	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:12941275
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	Cdk5	IMP		Mouse	MGI:MGI:3696283\|PMID:17143272
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16203963
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Cdk5	IDA		Rat	PMID:23699505\|RGD:13792535
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Cdk5	IMP		Rat	PMID:23699505\|RGD:13792535
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	Cdk5	IMP		Mouse	MGI:MGI:6094501\|PMID:24607229
Biological Process	GO:1905806	regulation of synapse pruning	Cdk5	EXP		Rat	PMID:17143272\|RGD:8554385
Biological Process	GO:1905806	regulation of synapse pruning	Cdk5	IDA		Rat	PMID:17143272\|RGD:8554385
Biological Process	GO:1905806	regulation of synapse pruning	Cdk5	IMP		Rat	PMID:17143272\|RGD:8554385
Biological Process	GO:0048167	regulation of synaptic plasticity	Cdk5	IMP		Rat	PMID:11675505\|RGD:69667
Biological Process	GO:0048167	regulation of synaptic plasticity	Cdk5	IMP		Rat	PMID:18498738\|RGD:8553496
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	Cdk5	IMP		Mouse	MGI:MGI:6094501\|PMID:24607229
Biological Process	GO:0042220	response to cocaine	Cdk5	IMP		Mouse	PMID:14769920
Biological Process	GO:0009611	response to wounding	Cdk5	IMP		Rat	PMID:14502288\|RGD:734740
Biological Process	GO:0010842	retina layer formation	cdk5	IMP	ZFIN:ZDB-MRPHLNO-090106-1	Zfish	PMID:18753621
Biological Process	GO:0014044	Schwann cell development	Cdk5	IMP	MGI:MGI:1861809	Mouse	PMID:16203963
Biological Process	GO:0019233	sensory perception of pain	Cdk5	IMP	MGI:MGI:3042874,MGI:MGI:3043819	Mouse	PMID:17194758
Biological Process	GO:0042501	serine phosphorylation of STAT protein	Cdk5	IDA		Mouse	PMID:15096606
Biological Process	GO:0007519	skeletal muscle tissue development	Cdk5	IDA		Mouse	PMID:9191048
Biological Process	GO:0007519	skeletal muscle tissue development	Cdk5	IEP		Rat	PMID:15208659\|RGD:1598429
Biological Process	GO:0007416	synapse assembly	Cdk5	IMP		Mouse	PMID:18054859
Biological Process	GO:0001963	synaptic transmission, dopaminergic	Cdk5	IMP		Mouse	PMID:14769920
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Cdk5	IMP		Mouse	PMID:14769920
Biological Process	GO:0048488	synaptic vesicle endocytosis	Cdk5	IMP		Rat	PMID:12855954\|RGD:1358501
Biological Process	GO:0021537	telencephalon development	Cdk5	IMP	MGI:MGI:1928281,MGI:MGI:3043819	Mouse	PMID:18032654
Biological Process	GO:0003309	type B pancreatic cell differentiation	cdk5	IMP	ZFIN:ZDB-GENO-190102-6	Zfish	PMID:28986398
Biological Process	GO:0008542	visual learning	Cdk5	IMP	MGI:MGI:3720892,MGI:MGI:3720937	Mouse	PMID:17529984

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.